| Tullie House Museum and Art Gallery Trust (Trading) Limited | Wholesale & retail | 2011 |
| Tumpline Limited | Information & communication | 1999 |
| Turnbull Stores Limited | Wholesale & retail | 2019 |
| Turnstone Drive Management Limited | Households | 2008 |
| Turtle Tots Cumbria Limited | Arts & recreation | 2018 |
| Tvfb (3) Limited | Transport & logistics | 1999 |
| Tvfb (4) Limited | Hospitality | 2020 |
| TVR Applications Limited | Administrative & support | 2014 |
| TVR Farming Ltd | Agriculture & fishing | 2024 |
| TVR Roofing & Construction Ltd | Construction | 2025 |
| TW Johnston | Agriculture & fishing | 2020 |
| Twenty Twenty Studio Ltd | Professional & scientific | 2026 |
| Twentyfoursevenclo Limited | Wholesale & retail | 2024 |
| Twentyman's Ices Limited | Manufacturing | 2003 |
| Twickenham Court Management Limited | Households | 2004 |
| Twinklepark Limited | Real estate | 1986 |
| Two Arches Limited | Hospitality | 2025 |
| Two Birdies Properties Limited | Real estate | 2024 |
| Two Castles Limited | Other services | 1985 |
| TWS Group Ltd | Construction | 2005 |
| Tynedale Insurance Services Ltd | Financial services | 2014 |
| Tynefield Court Management Limited | Households | 1995 |
| Tyrebin Limited | Professional & scientific | 2009 |
| Tyres R US (Carlisle) Ltd | Wholesale & retail | 2011 |
| Tyseley Heat Network Limited | Construction | 2025 |
| U Student (Carlisle) Ltd | Real estate | 2004 |
| U Student (Sunderland) Limited | Real estate | 2009 |
| U Student Group Ltd | Financial services | 2012 |
| Uber Entertainments Ltd | Hospitality | 2023 |
| Uber Hospitality Bars Ltd | Hospitality | 2023 |
| Udec Limited | Manufacturing | 2017 |
| UK & European Refrigerated Transport Limited | Transport & logistics | 2024 |
| UK Black Cat Ltd | Agriculture & fishing | 2011 |
| UK Buildlab Ltd | Information & communication | 2025 |
| UK Contracts Limited | | 2007 |
| UK Electrical Services (Carlisle) Ltd | Construction | 2013 |
| UK Fibre Networks (York) Ltd | Information & communication | 2018 |
| UK Generics Limited | Extraterritorial | 2009 |
| UK Karate Limited | Arts & recreation | 2012 |
| UK Opportunities Centre Ltd | Education | 2018 |
| UK Sleepover Ltd | Hospitality | 2025 |
| Uk.Kcd Ltd | Wholesale & retail | 2019 |
| Ukslings Ltd | Wholesale & retail | 2011 |
| Ulcatra Forestry Limited | Agriculture & fishing | 2022 |
| Ullesby Gardens Management Company Limited | Households | 2017 |
| Ultimate Security & Investigations Limited | Administrative & support | 1999 |
| Ultraviolet Salons Ltd | Other services | 2021 |
| UMA Kadampa Meditation Centre | Other services | 2001 |
| Uncle Sam’S Ice Cream Ltd | Manufacturing | 2025 |
| Under NO Illusion Limited | Arts & recreation | 2019 |
| Underfloor Heating Cumbria Ltd | Wholesale & retail | 2024 |
| Underwood Ventures Limited | Construction | 2023 |
| Underwoods Motorsport Ltd | Wholesale & retail | 2021 |
| Unest Limited | Real estate | 2015 |
| Uniclass Limited | Information & communication | 2021 |
| Uniquebuild Ltd | Construction | 2025 |
| United Kingdom Lung Cancer Coalition CIC | Health & social care | 2019 |
| United Loggers Limited | Extraterritorial | 2019 |
| Unity Rose Ltd | Real estate | 2023 |
| Universal Ground Solutions Limited | Construction | 2017 |
| Universal Trade Partners Limited | Professional & scientific | 2021 |
| Unwin Jones Limited | Professional & scientific | 2010 |
| Upper Air Ltd | Extraterritorial | 2017 |
| Upperby SC Ltd | Hospitality | 2024 |
| Uralensis INNOV8 Ltd | Information & communication | 2017 |
| Urban Excess Limited | Wholesale & retail | 2007 |
| Urban Preserves Limited | Hospitality | 2013 |
| Urban Sun Ltd | Other services | 2018 |
| USEDCAR4LESS Limited | Wholesale & retail | 2015 |
| Ushers Garage Limited | Wholesale & retail | 2011 |
| Utility Depot Limited | Energy | 2014 |
| Utopia Systems Ltd | Information & communication | 2018 |
| Uvory Floor Technologies Limited | Extraterritorial | 2013 |
| V Bar Limited | Hospitality | 2019 |
| V Nicholson Ltd | Real estate | 2026 |
| V&P Property Group Ltd | Real estate | 2025 |
| V.L. Seile Limited | Agriculture & fishing | 2014 |
| VAC EX Utilities UK Ltd | Construction | 2022 |
| Vagabond Developments Limited | Real estate | 2023 |
| Valley Developments and Construction Company Limited | Construction | 2010 |
| Valued Voices C.I.C. | Administrative & support | 2024 |
| Valuewear Stores Limited | Extraterritorial | 1972 |
| Van Diesel Limited | Wholesale & retail | 2024 |
| Van Giant Commercials Limited | Wholesale & retail | 2010 |
| Van Glass Ltd | Wholesale & retail | 2006 |
| Van Plus Limited | Extraterritorial | 2017 |
| Vanguard Tuesday Group Limited | Information & communication | 2023 |
| Vanti Camper Conversions Ltd | Wholesale & retail | 2025 |
| Vape Central Cumbria Limited | Wholesale & retail | 2026 |
| Vapestation Cumbria Limited | Wholesale & retail | 2023 |
| Vasa Limited | Real estate | 2025 |
| Vasi Solutions Limited | Information & communication | 2022 |
| VC Management Company Limited | Households | 2015 |
| Vebas Group Ltd | Transport & logistics | 2023 |
| Vecta C.N.C. Ltd | Manufacturing | 2005 |
| Vedela Property Limited | Real estate | 2024 |
| Vegan Events UK Limited | Administrative & support | 2021 |
| Venari Services Limited | Administrative & support | 2020 |
| Venator Financial Ltd | Financial services | 2021 |
| Venuscare Ltd | Real estate | 1997 |