| Speedcoat Limited | Professional & scientific | 2004 |
| Speedcoat-Europe- Limited | Manufacturing | 2012 |
| Speedliner (UK) Limited | Manufacturing | 2012 |
| Speedliner Europe Limited | Professional & scientific | 2004 |
| Speedlinings Ltd | Professional & scientific | 2006 |
| Speedtex Limited | Professional & scientific | 2004 |
| Spiritcymru Limited | Hospitality | 2020 |
| Star Foods Station Ltd | Hospitality | 2024 |
| Steff Agri Ltd | Wholesale & retail | 2025 |
| Steff Day Limited | Administrative & support | 2025 |
| Stet Fortuna Limited | Real estate | 2010 |
| Steve James Joinery Ltd | Manufacturing | 2003 |
| Steven Thomas Joinery Ltd | Manufacturing | 2009 |
| STIWDIO3 CIC | Hospitality | 2016 |
| Stockman Shepherd's Huts Ltd | Manufacturing | 2019 |
| Storm Development Limited | Information & communication | 2009 |
| Support in Your Home Ltd | Health & social care | 2022 |
| Survey IT (Wales) Limited | Professional & scientific | 2012 |
| Sussex Flats Limited | Real estate | 2001 |
| Swallow Boats Limited | Manufacturing | 2004 |
| Swallow Yachts Ltd | Wholesale & retail | 2018 |
| Sweet Hill Holidays Limited | Hospitality | 2019 |
| Sweetr Ltd | Professional & scientific | 2012 |
| Sychpant Limited | Agriculture & fishing | 2014 |
| T I D Holdings Limited | Construction | 2005 |
| T M Daniel Limited | Wholesale & retail | 2003 |
| T. I. Davies A'I FAB CYF. | Construction | 2002 |
| T21 Developments Ltd | Real estate | 2024 |
| Tafell Limited | Hospitality | 2025 |
| TAI Aberteifi Limited | Real estate | 2011 |
| TAI James Ltd | Real estate | 2024 |
| Tanygroes Car Dismantlers Limited | Wholesale & retail | 2005 |
| Teifi Chips Ltd | Hospitality | 2022 |
| Teifi Properties Limited | Real estate | 2024 |
| Teifi Valley Scaffolding Limited | Construction | 2003 |
| Tennis Coaching With Marco Limited | Education | 2025 |
| Thames Freedom Limited | Other services | 2011 |
| THE Accessible Web Ltd | Information & communication | 2023 |
| THE Amblin Partnership Limited | Construction | 2004 |
| THE Anchor Hotel (Gwbert) Limited | Hospitality | 1990 |
| THE Botanic Hub Ltd | Wholesale & retail | 2024 |
| THE Cabin Cardigan Ltd | Hospitality | 2023 |
| THE Computer Bay Ltd | Manufacturing | 2011 |
| THE DO Lectures Ltd | Arts & recreation | 2008 |
| THE Elemental Adventures Project CIC | Agriculture & fishing | 2018 |
| THE Feminine Principle Limited | Other services | 2022 |
| THE Gallery YR Oriel Newport Pembs Limited | Wholesale & retail | 2020 |
| THE Lighthouse Learning Project Community Interest Company | Arts & recreation | 2020 |
| THE Natural Tiler Limited | Construction | 2015 |
| THE One Plug Ltd | Manufacturing | 2019 |
| THE Pembrokeshire Cleaning Company Ltd | Administrative & support | 2021 |
| THE Pembrokeshire Holiday Company Ltd | Hospitality | 2020 |
| THE Pembrokeshire Property Company Ltd | Households | 2022 |
| THE Real Health Collective CIC | Education | 2024 |
| THE Trotters Lounge CIC | Health & social care | 2025 |
| THE Veteran Equine Trust Limited | Professional & scientific | 2003 |
| THE Williams Initiative Group Ltd | Financial services | 2026 |
| Thinkgreen.London Limited | Administrative & support | 2017 |
| Thomas Gardner Ltd | Real estate | 2020 |
| Thomas James (Cardigan) Limited | Hospitality | 1942 |
| Three Little Pigs Furniture & Home Ltd | Wholesale & retail | 2023 |
| Tides Kitchen & Wine Bar Ltd | Hospitality | 2020 |
| TIR CYD Ltd | Agriculture & fishing | 2025 |
| TL Generators Limited | Professional & scientific | 2025 |
| Tonnau Surf Limited | Wholesale & retail | 2017 |
| Tony James Limited | Construction | 2003 |
| Total Auto Concierge Ltd | Transport & logistics | 2022 |
| Total CDM Solutions Limited | Professional & scientific | 2001 |
| Train Miles Limited | Administrative & support | 2025 |
| Travain Limited | Construction | 2011 |
| Trebared CYF | Agriculture & fishing | 2009 |
| Trefor WYN 1973 Ltd | Hospitality | 2026 |
| Trefwtial Fawr CYF | Agriculture & fishing | 2009 |
| Trefynys Farm Limited | Agriculture & fishing | 2003 |
| Tregene Farm Limited | Agriculture & fishing | 2002 |
| Treiago Holiday Cottages Limited | Hospitality | 2012 |
| Trendbrick Limited | Construction | 2001 |
| TS Applications Ltd | Professional & scientific | 2026 |
| TY Canol Limited | Hospitality | 1984 |
| TY Cwrcoed LLP | | 2013 |
| TY Groes Cross House CYF. | Hospitality | 2014 |
| TY Parc International Limited | Extraterritorial | 2000 |
| TYB Farms Ltd | Agriculture & fishing | 2021 |
| Tygwyn Farm Limited | Agriculture & fishing | 2006 |
| TŶ Annie Ltd | Hospitality | 2021 |
| Uprise Media Limited | Professional & scientific | 2014 |
| Usta Takeaway Ltd | Hospitality | 2023 |
| UU3 Limited | Information & communication | 2007 |
| V2H V2G Solutions Ltd | Energy | 2024 |
| V2X Solutions Ltd | Construction | 2025 |
| Valecourt (Pembs) Limited | Real estate | 2024 |
| Veteran Horse National Championship Show Ltd | Arts & recreation | 2023 |
| Veteran Horse Society | Arts & recreation | 2001 |
| W.J. Williams & Davies Limited | Professional & scientific | 2011 |
| Water Street Carms Limited | Construction | 2026 |
| WE Builds Enterprises Limited | Construction | 2026 |
| Webstar (Europe) Limited | Real estate | 2005 |
| Welch & Co (Solicitors) Ltd | Professional & scientific | 2008 |
| West and Wales Decorating Centres Limited | Wholesale & retail | 2019 |
| West Coast Epc’S Ltd | Professional & scientific | 2020 |