| Sittingbourne Speedway Ltd | Other services | 2008 |
| SIX Tall Pines Limited | Professional & scientific | 2020 |
| SIX33 Limited | Administrative & support | 2019 |
| Sixteen Plus Limited | Health & social care | 2012 |
| SJ Wilson Holdings Ltd | Financial services | 2025 |
| SJL Properties Limited | Real estate | 2026 |
| SJP Ecology Limited | Professional & scientific | 2022 |
| SK Groups of Companys Limited | Wholesale & retail | 2025 |
| SK Holdings Kent Ltd | Real estate | 2025 |
| Skelton Aggregates Limited | Construction | 2022 |
| Skelton Agri Limited | Agriculture & fishing | 2022 |
| Skelton Concrete Limited | Construction | 2022 |
| Skelton Construction Limited | Construction | 2004 |
| Skelton Consulting Limited | Real estate | 2014 |
| Skelton Group Limited | Extraterritorial | 2015 |
| Skelton Plant Hire (West Kent) Limited | Professional & scientific | 2006 |
| Skelton Plant Hire Limited | Construction | 1998 |
| Skelton Storage Solutions Limited | Transport & logistics | 2022 |
| Skillconnectai Ltd | Information & communication | 2025 |
| Skills Qualifications Board Limited | Education | 2022 |
| Skills+ Healthcare Training Ltd | Education | 2014 |
| Skin Glossary Ltd | Information & communication | 2019 |
| Skmm Limited | Health & social care | 2021 |
| Sky Cleaning Services Limited | Other services | 2014 |
| Skybridge Civil Engineering Ltd | Construction | 2014 |
| Skyfreightglobal Ltd | Transport & logistics | 2025 |
| Skyhunter Property Limited | Administrative & support | 2016 |
| Skylark Escapes & Consultants Ltd | Real estate | 2022 |
| Skylark Kent (Wingham) Ltd | Construction | 2016 |
| Skylark Kent LLP | | 2017 |
| Skylark Rozel Ltd | Construction | 2016 |
| Skyline Business Support Services Limited | Professional & scientific | 2026 |
| Skyline Developments (South) Limited | Construction | 2023 |
| Skysill Technologies Limited | Information & communication | 2019 |
| SL World Limited | Wholesale & retail | 2021 |
| SLA Recruitment Consultants Limited | Administrative & support | 2015 |
| Slatters of Canterbury Limited | Administrative & support | 1988 |
| Slavikova Limited | Financial services | 2026 |
| Slavikova TPS Limited | Professional & scientific | 2026 |
| SLD (Canterbury) Limited | Hospitality | 2015 |
| Sleeptight Solutions Limited | Information & communication | 2026 |
| Sleepy Hollow (Whitstable) Limited | Extraterritorial | 2015 |
| Slipstream Logistics Limited | Administrative & support | 2024 |
| SLS Permanent Recruitment Limited | Administrative & support | 2020 |
| SLS Wills and More Limited | Other services | 2020 |
| SM Editorial Limited | Arts & recreation | 2021 |
| Small Fortune Estate Ltd | Real estate | 2024 |
| Smart Cabs Kent Ltd | Transport & logistics | 2025 |
| Smart Driving Solutions Ltd | Transport & logistics | 2025 |
| Smart MLM Services Ltd | Transport & logistics | 2018 |
| Smart Nails 19 Ltd | Other services | 2021 |
| Smart Nails Ltd | Other services | 2025 |
| Smart Phone Film School Ltd | Education | 2016 |
| Smart Socials Agency Ltd | Professional & scientific | 2025 |
| Smart Synced Ltd | Information & communication | 2025 |
| Smart Taxi App Ltd | Transport & logistics | 2016 |
| Smile Arch Limited | Health & social care | 2025 |
| Smile Labo Limited | Wholesale & retail | 2019 |
| Smith & Co Beauty Ltd | Other services | 2023 |
| Smith & Co Hair Ltd | Other services | 2018 |
| Smithfield Studio Ltd | Information & communication | 2021 |
| Smokey's Holding Ltd | Financial services | 2025 |
| Smokey’S Takeaway (Canterbury) Ltd | Hospitality | 2021 |
| Smove Property Solutions Ltd | Real estate | 2019 |
| SMR Kent Properties Ltd | Real estate | 2026 |
| Smugglers Events C.I.C. | Arts & recreation | 2019 |
| Snap Grid Limited | Construction | 2025 |
| Snazzy Pooch Ltd | Wholesale & retail | 2024 |
| Sneaky Duck Taverns Ltd | Hospitality | 2023 |
| Snmj Limited | Real estate | 2021 |
| Snowtart Ltd | Wholesale & retail | 2011 |
| Snug Installations Ltd | Construction | 2018 |
| SO Bella Holdings Limited | Real estate | 2012 |
| Soak House Ltd | Hospitality | 2025 |
| Soar Enterprise Holdings Ltd | Financial services | 2024 |
| Soar MEP Ltd | Professional & scientific | 2020 |
| Soarstar Company (UK) Ltd | Administrative & support | 2022 |
| Social Creatures Limited | Information & communication | 2013 |
| Sofiia Ltd | Wholesale & retail | 2025 |
| SOG Investments Ltd | Financial services | 2023 |
| Solar and Electrical Systems Ltd | Construction | 2022 |
| Solar Flair Limited | Construction | 2023 |
| Solar Plug Ltd | Wholesale & retail | 2026 |
| Solar South Ltd | Construction | 2024 |
| Solara Mediation Ltd | Professional & scientific | 2025 |
| Solarage UK Limited | Construction | 2009 |
| Solaris Energy Limited | Construction | 2017 |
| Solid Contract Solutions Ltd | Water & waste | 2024 |
| Solid Rock Media Ltd | Information & communication | 2024 |
| Soliman Construction Limited | Construction | 2015 |
| Solis Electrical Solutions Ltd | Construction | 2023 |
| Solution Circle Ltd | Construction | 2020 |
| Soma Partners Limited | Real estate | 2025 |
| Somerhall Limited | Financial services | 2004 |
| Somner Close Gardens Management Company Limited (the) | Households | 1968 |
| Songbird Wines Ltd | Wholesale & retail | 2018 |
| Soni G Limited | Health & social care | 2025 |
| Sons DE Bros Ltd | Wholesale & retail | 2024 |
| Sonya Winner Studio Ltd | Wholesale & retail | 1996 |
| Sophos Partners Limited | Professional & scientific | 2020 |