| Distribution, Maintenance & Storage Ltd | Transport & logistics | 2009 |
| Divine Elegance Beauty & Aesthetics Ltd | Other services | 2021 |
| DJ & PA Pennill (Holdings) Ltd | Water & waste | 2018 |
| DJ & PA Pennill Limited | Water & waste | 2011 |
| DJ Cloud Solutions Ltd | Information & communication | 2025 |
| DJ Defence Communications Ltd | Administrative & support | 2025 |
| DJH Accounting Services Limited | Professional & scientific | 2005 |
| DJH Interiors Limited | Construction | 2021 |
| DJS Property Construction Limited | Construction | 2024 |
| DJW Technology Ltd | Professional & scientific | 2023 |
| Djwg Ltd | Information & communication | 2013 |
| DKA Driveways & Patios Limited | Construction | 2024 |
| DLF Construction Solutions Limited | Construction | 2023 |
| DLF Property Solutions Limited | Real estate | 2022 |
| Dlsj Properties Limited | Construction | 2017 |
| Dm.Hr Group Limited | Professional & scientific | 2025 |
| DMA Freelance Ltd | Construction | 2017 |
| DMJ Electrical Installations Ltd | Construction | 2022 |
| DNA Dance LAB Ltd | Wholesale & retail | 2023 |
| DO the Thing Group Ltd | Administrative & support | 2017 |
| Dobson's Properties Limited | Real estate | 2025 |
| DOC Dave Limited | Health & social care | 2024 |
| Doctor Phoebe Ltd | Health & social care | 2024 |
| Documents & Data Limited | Information & communication | 2017 |
| Dolkan Homes Ltd | Construction | 2019 |
| Dolphin Personnel Ltd | Administrative & support | 2010 |
| Dominic Holdings Ltd | Real estate | 2024 |
| Doseley Halt Management Company Limited | Households | 2025 |
| Double UP Apparel Ltd | Wholesale & retail | 2020 |
| Dougie BOO Ltd | Information & communication | 2023 |
| Douglas Commercial Fabrications Limited | Manufacturing | 1996 |
| DP Medical Limited | Other services | 2016 |
| DPR Engineering Limited | Professional & scientific | 2022 |
| DR a C White Medical Services Ltd | Health & social care | 2010 |
| DR Composite Doors and Repairs Limited | Manufacturing | 2026 |
| DR Holdings & Property Limited | Real estate | 2025 |
| DR P Jalota Surgery GPF Limited | Professional & scientific | 2013 |
| DR Rasib Surgery GPF Limited | Professional & scientific | 2013 |
| DR S Manickam GPF Limited | Professional & scientific | 2019 |
| DR Sara Stokes Ltd | Administrative & support | 2017 |
| DR Sunni Ltd | Professional & scientific | 2021 |
| Drace Ltd | Households | 2024 |
| Dragonfly Residential Limited | Real estate | 2022 |
| Drake Court Healthcare Limited | Health & social care | 2000 |
| Drap Medical Ltd | Health & social care | 2021 |
| Dream Nails Hednesford Ltd | Other services | 2026 |
| Dreams Maid Ltd | Administrative & support | 2026 |
| Driver Network 24 / 7 Ltd | Transport & logistics | 2026 |
| Drivers 1ST Choice Limited | Education | 2026 |
| Drivetrain Supplies Limited | Wholesale & retail | 2010 |
| Driwall Finishers Limited | Construction | 2002 |
| DRM Property & Maintenance Limited | Construction | 2014 |
| Dronfield Singh Management Ltd | Real estate | 2026 |
| Dronfield Singh Properties Ltd | Real estate | 2024 |
| Drsv Investments Limited | Real estate | 2015 |
| Drsv Limited | Financial services | 2015 |
| Drsv Medicals Limited | Health & social care | 2014 |
| Dry-Tech RS Ltd | Construction | 2023 |
| DS Financial Management Limited | Financial services | 1999 |
| DS Trading (Cannock) Ltd | Wholesale & retail | 2015 |
| DSG Limited | Wholesale & retail | 2022 |
| DSJ Pipework Services Limited | Construction | 2018 |
| DSK Aviation Ltd | Manufacturing | 2016 |
| Dual Accountants Limited | Professional & scientific | 2015 |
| Duco Property Group Ltd | Real estate | 2025 |
| Ductile (UK) Ltd | Wholesale & retail | 2021 |
| Dudley Home Improvements Limited | Construction | 2025 |
| Dunston Investments Limited | Other services | 2015 |
| DUO Growth Media Ltd | Wholesale & retail | 2026 |
| DVA Ventures Limited | Professional & scientific | 2018 |
| DW Robotics Ltd | Professional & scientific | 2018 |
| Dwellz Ltd | Real estate | 2025 |
| Dyare Ltd | Wholesale & retail | 2025 |
| Dylan Evans Design Ltd | Professional & scientific | 2024 |
| Dynamo Fish & Chips Limited | Hospitality | 2025 |
| Dynasty Health Solutions Limited | Health & social care | 2025 |
| Dynomatik Limited | Information & communication | 2021 |
| E & S Tradecom Limited | Health & social care | 2003 |
| E a Response Ltd | Construction | 2023 |
| E Berry Floor Screeds Ltd | Construction | 2024 |
| E H Humphries Limited | Extraterritorial | 2010 |
| E H Humphries Mechanical Limited | Extraterritorial | 2008 |
| E J L Construction Limited | Construction | 2023 |
| E L Recruitment Solutions Limited | Administrative & support | 2017 |
| E P & T Bolton Plumbing & Heating Limited | Construction | 2010 |
| E Parton Ltd | Professional & scientific | 2023 |
| E Securities Rhiw Goch Ltd | Real estate | 2020 |
| E Seller Online Ltd | Wholesale & retail | 2022 |
| E&W Land & Property Co. Ltd | Real estate | 2025 |
| E-Securities Ltd | Hospitality | 2016 |
| E-Talking Club Limited | Information & communication | 2009 |
| E.C.S Computer Recycling Limited | Administrative & support | 2002 |
| E.H.Humphries(Norton)Limited | Construction | 1960 |
| E.M.L. Drywall Ltd | Construction | 2017 |
| E.O'Neill & SON Painting and Decorating Ltd | Construction | 2011 |
| E.P Fabrication Ltd | Manufacturing | 2019 |
| E20 Solutions Limited | Administrative & support | 2018 |
| EA ALL Seasons Landscapes Limited | Construction | 2018 |
| Ea.Serve. Ltd | Administrative & support | 2019 |
| Eagle Electrical Services (UK) Limited | Extraterritorial | 2003 |