| D&C Ventures Ltd | Real estate | 2025 |
| D&V Woodrow Ltd | Real estate | 2021 |
| D. Dyke & SON (Decorating Contractors) Limited | Construction | 1977 |
| D.A.S. (Midlands) Limited | Information & communication | 2011 |
| D.Edwards (Holdings) Limited | Financial services | 2024 |
| D.L Plumbing and Heating Solutions Ltd | Construction | 2018 |
| D.R Water Ltd | Water & waste | 2024 |
| D.S.I. Developments Ltd | Construction | 2018 |
| D365 Academy Ltd | Information & communication | 2019 |
| D6 Automotive Ltd | Wholesale & retail | 2020 |
| DA Mechanical & Hvac Services Ltd | Construction | 2021 |
| DAC Systems UK Limited | Manufacturing | 2022 |
| Dagem Power Ltd | Professional & scientific | 2014 |
| Dakin & SON Construction Ltd | Construction | 2019 |
| Dalaje Holdings Limited | Professional & scientific | 2026 |
| Dale Engineering Company,(Cannock),Limited(The) | Manufacturing | 1946 |
| Dales of Cannock Limited | Wholesale & retail | 1995 |
| Dama TS Ltd | Professional & scientific | 2024 |
| Damp Care Specialist Ltd | Construction | 2025 |
| DAN Haigh Prep Services Limited | Other services | 2021 |
| DAN Smith Carpentry Limited | Construction | 2014 |
| Daniel Designs Limited | Information & communication | 2021 |
| Daniel Holdings Limited | Extraterritorial | 2022 |
| Daniel Investment Group Limited | Real estate | 2024 |
| Danntech Limited | Manufacturing | 2008 |
| Danyfa Limited | Professional & scientific | 2024 |
| Darby Developments Limited | Real estate | 2023 |
| Dark World Design Ltd | Wholesale & retail | 2020 |
| Darkmattermerchants Ltd | Wholesale & retail | 2026 |
| Darkside Vintage Ltd | Wholesale & retail | 2021 |
| Darksidepool Ltd | Information & communication | 2026 |
| Darkstar Design and Engineering Services Ltd | Professional & scientific | 2022 |
| Data Modul Limited | Wholesale & retail | 2005 |
| Data Security Networks Ltd | Information & communication | 2023 |
| Data to Intelligence Ltd | Information & communication | 2019 |
| Datasystems (Midlands) Limited | Information & communication | 2008 |
| Dave's Motorhomes Services Ltd | Wholesale & retail | 2008 |
| Davep AV Limited | Professional & scientific | 2019 |
| David Blakemore Design Limited | Information & communication | 2000 |
| David Kettle Productions Limited | Arts & recreation | 2023 |
| David Leslie Bathrooms and Interiors Ltd | Construction | 2012 |
| Davies Consultant Neurology Services Ltd | Health & social care | 2024 |
| Davland Property Surveying Ltd | Professional & scientific | 2026 |
| DAW GAS Services Limited | Construction | 2015 |
| Dawn P. Evans Motels Limited | Hospitality | 2015 |
| Dawnstar Enterprises Limited | Extraterritorial | 2009 |
| Dawson Cooper Investments Ltd | Real estate | 2026 |
| Dawson Key Holdings Ltd | Financial services | 2023 |
| Dayle Peace Bespoke Ltd | Manufacturing | 2024 |
| DB Freelance Ltd | Transport & logistics | 2017 |
| DB Technical Solutions Ltd | Other services | 2014 |
| Dbell TSO Ltd | Construction | 2015 |
| Dbentley Holdings Limited | Real estate | 2023 |
| DC Builders(Cannock) Ltd | Construction | 2019 |
| DC Couries Limited | Transport & logistics | 2025 |
| DC Groundwork and Engineering Limited | Construction | 2026 |
| DDF Dance Company Limited | Arts & recreation | 2025 |
| Dealership Services Limited | Wholesale & retail | 2009 |
| Deckheadtradinguk Ltd | Wholesale & retail | 2022 |
| Decorative Finishings Limited | Construction | 2019 |
| Decorer Decorating Solutions Limited | Construction | 2024 |
| Decorer Limited | Construction | 2014 |
| Deda Infrastructure Ltd | Professional & scientific | 2022 |
| Delf Freezer Wear Limited | Manufacturing | 2002 |
| Delfi Services Ltd | Wholesale & retail | 2017 |
| Delphic Financial Planning Limited | Financial services | 2008 |
| Deluca Interiors Limited | Wholesale & retail | 2020 |
| Denia Developments Limited | Construction | 2015 |
| Denise Thorne's Mobile Play Therapy Ltd | Health & social care | 2014 |
| Dentaire Limited | Health & social care | 2006 |
| Deritend Tinning Limited | Professional & scientific | 1995 |
| Descom Limited | Information & communication | 2003 |
| Design 380 Limited | Information & communication | 2011 |
| Designer Construction Solutions Limited | Professional & scientific | 2004 |
| Desire Services Ltd | Health & social care | 2020 |
| Deskless Ltd | Information & communication | 2026 |
| Dessertville Limited | Manufacturing | 2025 |
| Deutz UK Ltd | Wholesale & retail | 1952 |
| DEW Solutions Ltd | Professional & scientific | 2021 |
| Dewcross Limited | Construction | 2000 |
| Dexterose Limited | Real estate | 1983 |
| DG Electrical Installations Limited | Construction | 2022 |
| DH Heating Limited | Construction | 2004 |
| Dharam 13 Properties Ltd | Real estate | 2020 |
| Diamond Scissors 1 Ltd | Other services | 2024 |
| Dicesare Distributions Ltd | Wholesale & retail | 2024 |
| Diduo UK Ltd | Wholesale & retail | 2025 |
| Diesel TEK Ltd | Wholesale & retail | 2018 |
| Digital Logic Ltd | Information & communication | 2023 |
| Digital Media Assist Limited | Information & communication | 2016 |
| Diligent Building Solutions Limited | Construction | 2023 |
| Dinolote Aviation Solutions Limited | Professional & scientific | 2009 |
| Direct Assurance Training Ltd | Professional & scientific | 2020 |
| Direct Bedrooms (West Mids) Ltd | Manufacturing | 2012 |
| Direct GP Locums Limited | Health & social care | 2010 |
| Direct Vehicle Security Ltd | Wholesale & retail | 2024 |
| Directcommerce Limited | Administrative & support | 2026 |
| Dirty INK Publishing Ltd | Information & communication | 2021 |
| Disable Aids (Cannock) Limited | Wholesale & retail | 2020 |
| Distinctly Individual Ltd | Manufacturing | 2015 |