| Erbi Limited | Extraterritorial | 2009 |
| Ergatic 0 Ltd | Information & communication | 2021 |
| Ergatic Labs Ltd | Professional & scientific | 2021 |
| Ergatic Ltd | Financial services | 2021 |
| Ergo Design Ltd | Professional & scientific | 2022 |
| Ergo Propter HOC Ltd | Professional & scientific | 2022 |
| Ergolux Limited | Manufacturing | 2024 |
| Ergotomics Limited | Wholesale & retail | 2013 |
| Erika & Fiffy Truck Ltd | Transport & logistics | 2021 |
| Erimus Consultants Limited | Information & communication | 2005 |
| Erin Timber Ltd | Wholesale & retail | 2024 |
| ERL (Red House Ripon) Limited | Construction | 2016 |
| ERL (Worcester) Ltd | Construction | 2017 |
| Ermine Street Housing Limited | Extraterritorial | 2014 |
| Ermine Street Properties Ltd | Households | 2023 |
| Erms (UK) Investments Limited | Professional & scientific | 2023 |
| Ernest Media Ltd | Information & communication | 2016 |
| ERP Mechanics UK Limited | Information & communication | 2025 |
| Errantsoft Ltd | Information & communication | 2020 |
| Ersin Cambridge Construction Ltd | Other services | 2021 |
| Ertner Audio Consultants Limited | Professional & scientific | 2008 |
| Ervis Construction Ltd | Construction | 2020 |
| Eryk Sokolowski Ltd | Manufacturing | 2025 |
| Eryri BIO Limited | Professional & scientific | 2026 |
| Escapade 29 Ltd | Construction | 2023 |
| Escapade 32 Ltd | Construction | 2024 |
| Escapade 37 Ltd | Construction | 2023 |
| Escapade Holidays Limited | Administrative & support | 2015 |
| Escapade SPV Limited | Financial services | 2023 |
| Escape Engines Ltd | Information & communication | 2018 |
| Eshine International Trading Co., Ltd | Extraterritorial | 2017 |
| Esker Technology Limited | Manufacturing | 2016 |
| Eslinah and Kiruthikan Gold Retail Ltd | Manufacturing | 2023 |
| Esoglass Limited | Professional & scientific | 2023 |
| Esona Tech Ltd | Professional & scientific | 2022 |
| Esoteric Audio Research Limited | Extraterritorial | 1995 |
| Esox Consulting Limited | Professional & scientific | 2025 |
| Espeed Global Ltd | Extraterritorial | 2014 |
| Esplora Limited | Administrative & support | 2008 |
| Esra Property Services Limited | Real estate | 2010 |
| Essanoor Associates Private Limited | Professional & scientific | 2025 |
| Esscotti Limited | Wholesale & retail | 2004 |
| Essential Cambridge L.P. | | 2025 |
| Essential Italy Limited | Hospitality | 2002 |
| Essential Staging Limited | Arts & recreation | 2019 |
| Essentialz Limited | Wholesale & retail | 2006 |
| Essex and Cambridge Events Limited | Arts & recreation | 2025 |
| Essor Technologies Limited | Information & communication | 2026 |
| Estelle’S Make-Up & Beauty Ltd | Other services | 2019 |
| Estimable Ltd. | Information & communication | 2020 |
| Estmanco (White Horse Lane) Freehold Limited | Real estate | 2013 |
| Estmanco (White Horse Lane) Limited | Real estate | 1980 |
| Estrella Holdings Ltd | Real estate | 2024 |
| Estuate Limited | Information & communication | 2009 |
| Esze Ltd | Other services | 2024 |
| ET Capital Directors Limited | Extraterritorial | 2024 |
| ET Capital Limited | Financial services | 1988 |
| ET Press Ltd | Information & communication | 2022 |
| Et&I Ltd | Manufacturing | 2026 |
| Et-Traps Limited | Professional & scientific | 2015 |
| ETC Ltd | Extraterritorial | 2023 |
| Etchara Ltd | Administrative & support | 2021 |
| Eterika Ltd | Health & social care | 2021 |
| Etgala Technology Co., Ltd | Wholesale & retail | 2023 |
| Ethernet Limited | Information & communication | 2005 |
| Ethicronics Ltd | Information & communication | 2022 |
| Ethiopia Foresight Ltd | Information & communication | 2018 |
| Ethnic Rysha Limited | Wholesale & retail | 2023 |
| Ethnical Limited | Health & social care | 2015 |
| Etmarine Engineering & Services Co., Limited | Wholesale & retail | 2020 |
| Eton Green Management Company Limited | Households | 2007 |
| ETS Systems UK Limited | Real estate | 2011 |
| Eugen Capra Ltd | Manufacturing | 2024 |
| Euklid Ltd | Financial services | 2017 |
| Eunoia Coffee Limited | Hospitality | 2024 |
| EUR Mining Group Ltd | Agriculture & fishing | 2021 |
| Eurasian Academy of Engineering Sciences | Professional & scientific | 2025 |
| Euro Chemical Industry Group Trading Ltd | Mining & quarrying | 2021 |
| Euro FD UK Limited | Real estate | 2013 |
| Euro Racing Wheels Co Ltd | Extraterritorial | 2013 |
| Europa Hamster International Limited | Extraterritorial | 2012 |
| Europa Science Holdings Limited | Professional & scientific | 2021 |
| Europa Science Limited | Information & communication | 2002 |
| Europe Ineos UK Industrial Group Limited | Mining & quarrying | 2026 |
| Europe Langton Group Ltd | Manufacturing | 2020 |
| Europe Lion Horse Benofon Chemical Co., Ltd | Wholesale & retail | 2023 |
| Europe Pules Chemical Co., Ltd | Manufacturing | 2021 |
| Europe Shrew Agrochemical Co., Ltd | Wholesale & retail | 2023 |
| Europe Sitaike Special Fertilizer Ltd | Extraterritorial | 2020 |
| Europe Yaya CIC | Education | 2022 |
| European Artificial Intelligence Industry Development Group Ltd | Information & communication | 2025 |
| European Chemical Plant Nutrition Co., Limited | Wholesale & retail | 2025 |
| European Chemical Specialty Fertilizer International Limited | Extraterritorial | 2024 |
| European College of Veterinary Pharmacology & Toxicology Ltd. | Professional & scientific | 2010 |
| European Connectivity Networks UK Ltd | Information & communication | 2022 |
| European Eternal Commodity Co., Ltd | Extraterritorial | 2011 |
| European Potash Mining Industry Group Co., Ltd | Wholesale & retail | 2023 |
| European Property Systems Limited | Real estate | 2006 |
| European Sphs BIO Co., Ltd | Mining & quarrying | 2025 |
| European Veterinary Dental College Ltd | Professional & scientific | 2009 |