| Elpi Consulting Limited | Hospitality | 2019 |
| Elpie Bannister Coaching Ltd | Professional & scientific | 2025 |
| Elrig UK Limited | Administrative & support | 2005 |
| Elro Digital Limited | Wholesale & retail | 2014 |
| Elsaa Ltd | Education | 2025 |
| Elsiem Limited | Manufacturing | 2012 |
| Eltofore Ltd | Information & communication | 2010 |
| Eltr Electrical Limited | Construction | 2025 |
| Elucidare Limited | Professional & scientific | 2004 |
| Elucigen Limited | Administrative & support | 2000 |
| Elvin Composites Ltd | Manufacturing | 2026 |
| Elvison Limited | Real estate | 2019 |
| Elway Properties Limited | Real estate | 2024 |
| Elwin Composites Ltd | Manufacturing | 2026 |
| Elwood FM Limited | Financial services | 2019 |
| ELY and District Model Railway Club Ltd | Other services | 2019 |
| ELY Chamber of Commerce Limited | Professional & scientific | 2005 |
| ELY Grazing Company Limited | Wholesale & retail | 2021 |
| ELY House 25 Ltd | Information & communication | 2025 |
| Elysian Hostess Ltd | Hospitality | 2024 |
| Elysian Leadership Ltd | Education | 2025 |
| Elysian Souls Ltd | Wholesale & retail | 2025 |
| Emaan's Grill Kitchen Ltd | Hospitality | 2026 |
| Emad Group Ltd | Wholesale & retail | 2024 |
| Emaginations Consulting Limited | Education | 2021 |
| Emanja Limited | Professional & scientific | 2024 |
| EMB Strategies Ltd | Professional & scientific | 2025 |
| Embassy Educational Services (UK) Limited | Education | 1981 |
| Embassy Lettings and Management Limited | Real estate | 2014 |
| Embe Aviation Ltd | Manufacturing | 2025 |
| Embeddededge Consulting Ltd | Professional & scientific | 2025 |
| Ember Dynamics Ltd | Financial services | 2025 |
| Emberion Limited | Professional & scientific | 2016 |
| Emberwell Enterprises Ltd | Administrative & support | 2026 |
| EMC Air Global Ltd | Manufacturing | 2025 |
| EMC Motor Limited | Professional & scientific | 2020 |
| Emed Genomics Ltd | Information & communication | 2025 |
| Emerald Foods Ltd | Wholesale & retail | 2001 |
| Emerex Trading Limited | Wholesale & retail | 2025 |
| Emergence NOW Ltd | Professional & scientific | 2018 |
| Emerging Affairs Consulting Limited | Professional & scientific | 2022 |
| Emergo Consulting (UK) Limited | Professional & scientific | 2001 |
| Emerita Properties Limited | Construction | 2013 |
| Emerson Industry Ltd. | Manufacturing | 2024 |
| Emerson Park (Great Abington) Management Company Ltd | Households | 2020 |
| EMI Automotive Ltd | Wholesale & retail | 2025 |
| EMI International Ltd | Professional & scientific | 2023 |
| Emily Farnworth Ltd | Professional & scientific | 2022 |
| Emilyai Ltd | Information & communication | 2026 |
| Eminaco Aviation Ltd | Manufacturing | 2020 |
| Emination Ltd | Professional & scientific | 2018 |
| Emmap Ltd | Health & social care | 2026 |
| Emmaus Cambridge (Homes) Limited | Real estate | 2018 |
| Emmett Investments Ltd | Real estate | 2018 |
| Emopaw Limited | Manufacturing | 2025 |
| Emphasis Property Ltd | Real estate | 2018 |
| Empire Elite Estates Limited | Real estate | 2024 |
| Empire Home Improvements Cambs Ltd | Construction | 2024 |
| Empisti Consultancy Ltd | Professional & scientific | 2025 |
| Employer Consulting Group Limited | Professional & scientific | 2010 |
| Employer Consulting Limited | Professional & scientific | 2010 |
| Empower Accountancy (Cambridge) Ltd | Professional & scientific | 2025 |
| Empower Foundation (East Anglia) Ltd | Other services | 2026 |
| Emson Property Investments Limited | Construction | 1984 |
| Emsys Properties Ltd | Real estate | 2023 |
| EMZ Ltd | Health & social care | 2014 |
| Enable Automation Limited | Professional & scientific | 2020 |
| Enabling Place Ltd | Professional & scientific | 2024 |
| Enachecornel Ltd | Manufacturing | 2026 |
| Enactium Ltd | Professional & scientific | 2026 |
| Enasescu Ltd | Manufacturing | 2023 |
| Enavix Ltd | Wholesale & retail | 2025 |
| Enceladus Associates Limited | Professional & scientific | 2010 |
| Encentive Ltd | Manufacturing | 2022 |
| Enchanted Cinema Limited | Arts & recreation | 2015 |
| Encoded Solutions Ltd | Information & communication | 2026 |
| Encompass NOW Ltd | Education | 2011 |
| Encore Commercial Limited | Extraterritorial | 2015 |
| Encore Estate Management Limited | Real estate | 2003 |
| Encore PM Group (Bidco) Ltd | Financial services | 2021 |
| Encore PM Group (Holdco) Ltd | Financial services | 2021 |
| Encore PM Group (Midco) Ltd | Financial services | 2020 |
| Encore PMG Limited | Financial services | 2004 |
| Encore Property Management Group Ltd | Financial services | 2020 |
| Enden Marine Carpentry Ltd | Manufacturing | 2022 |
| Endoenergy Systems Limited | Manufacturing | 2002 |
| Endomagnetics Ltd | Manufacturing | 2007 |
| Endorsement Limited | Administrative & support | 2009 |
| Endurance Sports Research Limited | Information & communication | 2016 |
| Enduring Missions Ltd | Professional & scientific | 2021 |
| Enedra Therapeutics Limited | Professional & scientific | 2021 |
| Energi Electrical Limited | Construction | 2009 |
| Energineering Ltd | Professional & scientific | 2020 |
| Energy ARK Ltd | Professional & scientific | 2023 |
| Energy Business Catalyst Ltd | Professional & scientific | 2015 |
| Energy Mining Advisory Partnership Ltd | Mining & quarrying | 2020 |
| Energy Simulation Solutions Ltd | Information & communication | 2013 |
| Energysor Ltd | Professional & scientific | 2024 |
| Energywork Universal Ltd | Health & social care | 2024 |
| Engage Consulting Limited | Administrative & support | 2000 |