| Devantier Group Limited | Professional & scientific | 2008 |
| Devantier Properties Limited | Real estate | 1988 |
| Devicechooser Ltd | Information & communication | 2019 |
| Devil's Fit Camp Ltd | Information & communication | 2025 |
| Devon Country Parks Ltd | Real estate | 2025 |
| Devonshire Gardens Taplow Limited | Households | 2013 |
| Devonshire Property Management Company Limited | Households | 2018 |
| Devonshire Road Transport Limited | Transport & logistics | 2018 |
| Devote Software Ltd | Information & communication | 2018 |
| Devquest Ltd | Information & communication | 2026 |
| Devson's &Co Ltd | Hospitality | 2026 |
| DEW Point Systems Ltd | Manufacturing | 2025 |
| DEX Carpentry Ltd | Extraterritorial | 2024 |
| Deyton Bell Business Services Limited | Extraterritorial | 2005 |
| Deyton Bell Consultancy Services Limited | Extraterritorial | 2005 |
| Deyton Bell Employee Services Limited | Extraterritorial | 2005 |
| Deyton Bell Financial Services Limited | Extraterritorial | 2005 |
| Deyton Bell Global Limited | Professional & scientific | 2019 |
| Deyton Bell Limited | Professional & scientific | 2005 |
| Deyton Bell Ventures Limited | Extraterritorial | 2005 |
| Deyu International Trading Co., Ltd | Wholesale & retail | 2025 |
| DFG Assets Partnerships Ltd | Manufacturing | 2018 |
| DFK Systems Ltd | Information & communication | 1999 |
| DFU Technology Ltd | Administrative & support | 2012 |
| DG Composites Ltd | Manufacturing | 2017 |
| DGB International Limited | Professional & scientific | 2008 |
| DGH TAS Groups Ltd | Hospitality | 2019 |
| DGL Aviation Ltd | Manufacturing | 2026 |
| DGL Developments Limited | Construction | 2003 |
| Dgr.Aviation. Ltd | Manufacturing | 2026 |
| DH Building Consultancy Ltd | Professional & scientific | 2024 |
| DH Dullingham Limited | Construction | 2024 |
| DH Electrical Cambridge Ltd | Construction | 2024 |
| Dhanda Enterprise Ltd | Real estate | 2022 |
| Dhankison Technologies Ltd | Information & communication | 2022 |
| Dhannan Composites Ltd | Manufacturing | 2025 |
| Dhanush Limited | Hospitality | 2026 |
| DHD (Europe) Limited | Administrative & support | 2000 |
| Dhewha Driving Ltd | Education | 2026 |
| Dhlure Ltd | Manufacturing | 2025 |
| Dhruv Properties Ltd | Real estate | 2018 |
| Dhruvanshboutique Ltd | Wholesale & retail | 2025 |
| Diagnodus Ltd | Professional & scientific | 2011 |
| Diagnostic Clinops Consulting Ltd | Professional & scientific | 2026 |
| Diagnosys UK Ltd. | Wholesale & retail | 1996 |
| Diaier Trading Co., Ltd | Wholesale & retail | 2024 |
| DIAL2GO Ltd | Administrative & support | 2026 |
| Dialogic Space Ltd | Education | 2024 |
| Diamond Business Solutions Ltd | Manufacturing | 2012 |
| Diamond-Clarity Consultants Limited | Professional & scientific | 2016 |
| Diana Reis Ltd | Professional & scientific | 2020 |
| Diar Store Ltd | Wholesale & retail | 2018 |
| Diasporas, Immigrants, Refugees and Emigrants (Dire) Heritage CIC | Administrative & support | 2015 |
| Diba Industries Limited | Manufacturing | 1973 |
| Dibi Global Limited | Hospitality | 2025 |
| Dice Services Limited | Construction | 2022 |
| Dickinson & Gallop Ltd | Real estate | 2016 |
| Dicksons of Cambridge Ltd | Construction | 1999 |
| Dictum Factum Ltd | Manufacturing | 2025 |
| Didcot Property (SMT) Ltd | Real estate | 2016 |
| Didi&Sami Ltd | Manufacturing | 2025 |
| Didiano Properties Services Limited | Real estate | 2026 |
| Didiano Services Limited | Wholesale & retail | 2025 |
| Diem Wills & Estate Planning Ltd | Professional & scientific | 2026 |
| Diep Tran Consultancy Ltd | Manufacturing | 2012 |
| Diep Tran Properties Limited | Real estate | 2017 |
| Diesel Maritech UK Co., Ltd | Manufacturing | 2024 |
| Diez-Cowell Consultants Ltd | Professional & scientific | 2016 |
| Difara Ltd | Construction | 2018 |
| Different Angles Limited | Professional & scientific | 2020 |
| DIG Shovel DIG Limited | Professional & scientific | 2018 |
| Digby Avenue Management Company Limited | Households | 2003 |
| Digi Pens Ltd | Wholesale & retail | 2020 |
| Digiarty Ltd | Extraterritorial | 2016 |
| Digital Assetz Limited | Information & communication | 2025 |
| Digital Decor UK Limited | Construction | 2007 |
| Digital Doctrine Ltd | Information & communication | 2019 |
| Digital Game Factory Limited | Information & communication | 2023 |
| Digital Guides Limited | Information & communication | 2003 |
| Digital Health Luminary Ltd | Information & communication | 2022 |
| Digital Hobo Limited | Information & communication | 2026 |
| Digital Influx Asia Limited | Education | 2020 |
| Digital Influx International Limited | Education | 2020 |
| Digital Influx Limited | Extraterritorial | 2018 |
| Digital Insight Technologies Ltd | Information & communication | 2018 |
| Digital Media Connect Limited | Information & communication | 2015 |
| Digital Print Solutions Limited | Manufacturing | 2024 |
| Digital Resilience UK Ltd | Information & communication | 2019 |
| Digital Scientific UK Limited | Wholesale & retail | 2002 |
| Digital Services Cambridge Limited | Information & communication | 2011 |
| Digital WG Ltd | Professional & scientific | 2021 |
| DIGITAL4PROFIT Ltd | Professional & scientific | 2025 |
| Digney Developments Limited | Construction | 2023 |
| Dijie Global Trade Ltd | Wholesale & retail | 2024 |
| Dileas Ltd | Other services | 2014 |
| Dillpon Limited | Real estate | 2022 |
| Dilun Clothing Co., Ltd | Wholesale & retail | 2024 |
| Dima Consulting Ltd | Manufacturing | 2026 |
| Dimaxer Technology Ltd | Information & communication | 2018 |
| Dimension Technologies (UK) Limited | Information & communication | 2020 |