| David Britnell Eventing Ltd | Agriculture & fishing | 2024 |
| David Butler (Agricultural Contracting) Limited | Agriculture & fishing | 1977 |
| David Clayton Engineering Consultant Limited | Construction | 2008 |
| David Hall Bespoke Furniture Limited | Manufacturing | 2004 |
| David Kingsbury Ltd | Arts & recreation | 2022 |
| David Osborn Architects Ltd | Professional & scientific | 2021 |
| David Pryke Motor Repairs Limited | Wholesale & retail | 2002 |
| David Reed Homes Limited | Construction | 2024 |
| David Scotcher Interiors Ltd | Wholesale & retail | 2008 |
| David Turner Legal Services Ltd | Professional & scientific | 2012 |
| David&Melisa Ltd | Manufacturing | 2025 |
| Davidhugh Limited | Manufacturing | 2013 |
| Davis Projects Limited | Construction | 2026 |
| Davron Supply Ltd | Wholesale & retail | 2026 |
| Dawnhart Limited | Health & social care | 2018 |
| Dawson-Church Consulting Limited | Professional & scientific | 2023 |
| Daybreak Productions Ltd | Extraterritorial | 2023 |
| Daycom Management Services Limited | Professional & scientific | 1998 |
| Dazzle Light Sky Co., Ltd | Wholesale & retail | 2023 |
| DB Camrisk Ltd | Professional & scientific | 2025 |
| DB Composites Ltd | Manufacturing | 2022 |
| DB Contracting (Cambs) Limited | Agriculture & fishing | 2020 |
| DB Developments (Cambridge) Ltd | Information & communication | 2012 |
| DB Global Events CIC | Information & communication | 2024 |
| DB Laminator and Finisher Ltd | Wholesale & retail | 2026 |
| DB Scientific Ltd | Information & communication | 2021 |
| DBA Group Limited | Professional & scientific | 2003 |
| Dbdh Co (UK) Limited | Health & social care | 2023 |
| Dbih Holdings Limited | Manufacturing | 2017 |
| Dbjfba Ltd | Wholesale & retail | 2026 |
| Dblx Limited | Information & communication | 2013 |
| DBM Property Holdings Ltd | Real estate | 2021 |
| DBS Electrical (Cambridge) Limited | Construction | 2011 |
| DBS Office Solutions Ltd | Wholesale & retail | 2019 |
| DC Aerotechnics Ltd | Manufacturing | 2025 |
| Dc-Unit Ltd | Health & social care | 2024 |
| DCB Capital Ltd | Real estate | 2022 |
| Dchl Services Limited | Construction | 2018 |
| Dchu Limited | Professional & scientific | 2013 |
| DCT Media Ltd | Information & communication | 2025 |
| DD Fried Chicken Ltd | Hospitality | 2020 |
| DD Mechanical Projects Ltd | Construction | 2017 |
| Ddab Investment Company Ltd | Real estate | 2026 |
| DDD Landscapes Ltd | Administrative & support | 2021 |
| DDH Screening Ltd | Health & social care | 2022 |
| DDM Consultants Limited | Professional & scientific | 2018 |
| DDN Global Ltd | Information & communication | 2024 |
| DDS Aviation Ltd | Manufacturing | 2024 |
| DDS Verse Ltd | Wholesale & retail | 2025 |
| DDY932 Limited | Hospitality | 2023 |
| DE Berniere Ltd | Financial services | 2021 |
| DE Blaca Limited | Information & communication | 2018 |
| DE CAI Honorise New Material Co., Ltd | Professional & scientific | 2018 |
| DE Curieres Services Ltd | Manufacturing | 2025 |
| DE Freville (Cambridge) Management Company Limited | Real estate | 2013 |
| DE Freville Court Management Company Limited | Extraterritorial | 1996 |
| DE Freville Sandy Lane Limited | Real estate | 2016 |
| DE Havilland Gardens (Huntingdonshire) Management Company Limited | Real estate | 2020 |
| DE Iannello Ltd | Education | 2024 |
| DE Lacey Heights Residents Association Limited | Households | 2003 |
| DE Simone Mitchell Developments Ltd | Real estate | 2005 |
| DE Villiers Family Office Limited | Real estate | 2021 |
| DEA Cambridge Limited | Professional & scientific | 2008 |
| Deafnalised Ltd | Wholesale & retail | 2025 |
| Deakin Parker Investments Limited | Real estate | 2019 |
| Deakin Parker Ltd | Professional & scientific | 2016 |
| Dean Bartram Agricultural Contractors Limited | Agriculture & fishing | 2015 |
| Dean House (Reading) Management Company Limited | Households | 2005 |
| Dean Moss Books Ltd | Information & communication | 2025 |
| Deane Management (Cambridge) Limited | Professional & scientific | 2022 |
| Deanreel Limited | Real estate | 2022 |
| Deany&Anamaria Limited | Construction | 2019 |
| Deaton Global Ventures Ltd | Wholesale & retail | 2026 |
| Debao Limited | Extraterritorial | 2023 |
| Debbie Air Ltd | Manufacturing | 2016 |
| Debbie Larrad Limited | Professional & scientific | 2019 |
| Debnam Brickworks Limited | Real estate | 2001 |
| Debnam Estates Limited | Real estate | 2008 |
| Debondt Limited | Construction | 2010 |
| Deboyce Limited | Information & communication | 1988 |
| Debt & Money Advice Support CIC | Financial services | 2014 |
| Dec's Kitchen Limited | Hospitality | 2014 |
| Decaura Limited | Information & communication | 2017 |
| Decclesis Ltd | Wholesale & retail | 2026 |
| Decentservices Ltd | Information & communication | 2010 |
| Decision Intelligence Solutions Ltd | Professional & scientific | 2025 |
| Decm UK Ltd | Administrative & support | 2026 |
| Decor-Master Limited | Construction | 2025 |
| Decurion Security Ltd | Manufacturing | 2025 |
| Dediterra Ltd | Wholesale & retail | 2018 |
| Deep Deep Ltd | Manufacturing | 2025 |
| Deep Footprints Digital Ltd | Professional & scientific | 2010 |
| Deep Look Co., Ltd | Wholesale & retail | 2025 |
| Deep River Development Limited | Information & communication | 2011 |
| Deep Roots Technologies Ltd | Information & communication | 2024 |
| Deep Thought Ltd | Information & communication | 2020 |
| Deep Time Ltd | Professional & scientific | 2026 |
| Deepform Limited | Professional & scientific | 2022 |
| Deeppsi Ltd | Information & communication | 2025 |
| Deeprole Limited | Information & communication | 2024 |