| Sfim Limited | Construction | 2023 |
| SFR Logistics Ltd | Real estate | 2026 |
| SFS33 Ltd | Professional & scientific | 2024 |
| SG Advisory Limited | Professional & scientific | 2011 |
| SG Smart Home Solutions Ltd | Real estate | 2024 |
| SGD Site Engineering and Surveys Ltd | Professional & scientific | 2012 |
| SGF Cambridge Limited | Professional & scientific | 2016 |
| SGF Excavations Ltd | Construction | 2022 |
| Sgmc Consulting Limited | Information & communication | 2013 |
| Sgrom Limited | Construction | 2023 |
| Sh-Steel International Co., Limited | Manufacturing | 2024 |
| Shachi Hardware Co., Ltd | Wholesale & retail | 2024 |
| Shade Ltd | Extraterritorial | 2023 |
| Shadeex Ltd | Construction | 2023 |
| Shadestation Ltd | Extraterritorial | 2023 |
| Shadow Entreprise Ltd | Wholesale & retail | 2026 |
| Shaggy Dog Ltd | Information & communication | 2005 |
| Shaheenkada Limited | Real estate | 2025 |
| Shakespeare Lodge TLA Limited | Hospitality | 2001 |
| Shakti Properties Limited | Real estate | 2016 |
| Shalva Care Ltd | Public administration | 2024 |
| Shalva Connect Ltd | Administrative & support | 2025 |
| Shamir UK Limited | Manufacturing | 1988 |
| Shamslab Ltd | Information & communication | 2024 |
| Shanard Ltd | Agriculture & fishing | 2009 |
| Shandong Danyuan Trading Co., Ltd | Extraterritorial | 2023 |
| Shandong Goldgain International Trading Ltd | Manufacturing | 2019 |
| Shandong Haihuitong International Trade Limited | Wholesale & retail | 2024 |
| Shandong Hontai Steel Co., Ltd | Extraterritorial | 2021 |
| Shandong Huiyao Technology New Material Co., Ltd | Manufacturing | 2023 |
| Shandong Polymer Additives Co., Ltd | Extraterritorial | 2014 |
| Shandong Ruisheng Glass Products Co., Ltd. | Wholesale & retail | 2025 |
| Shang HAI SI EN KAI Bearing Co., Ltd | Manufacturing | 2023 |
| Shang WEI Food Ltd | Hospitality | 2023 |
| Shangding Shoes and BAG Co., Ltd | Extraterritorial | 2024 |
| Shanghai Afpak Co., Ltd | Extraterritorial | 2014 |
| Shanghai Changkuan Co., Ltd | Wholesale & retail | 2026 |
| Shanghai Full Housewares Co., Ltd | Extraterritorial | 2014 |
| Shanghai Fusheng Industrial Co., Ltd | Extraterritorial | 2013 |
| Shanghai Grand Enterprise Co., Ltd. | Extraterritorial | 2018 |
| Shanghai Qiyi International Trade Company Limited | Other services | 2021 |
| Shanghai Safetec Marine Services Co., Ltd | Wholesale & retail | 2025 |
| Shanghai Vulcan Industrial Co., Ltd | Extraterritorial | 2016 |
| Shanghai Tengxun Shipping Engineering Co., Ltd | Wholesale & retail | 2024 |
| Shangxiang Trading Limited | Wholesale & retail | 2020 |
| Shani Robbins TM Ltd | Construction | 2025 |
| Shanid Limited | Real estate | 2022 |
| Shanks Gold and Silver Ltd | Wholesale & retail | 2024 |
| Shans Green Ltd | Wholesale & retail | 2018 |
| Shanxi Yuhong Metal Products Co., Ltd | Extraterritorial | 2018 |
| Shao TAO Limited | Financial services | 2025 |
| Shaoxing Keqiao Ruien Home&Textile Co., Ltd | Extraterritorial | 2021 |
| Shape of Sound Ltd | Information & communication | 2011 |
| Shappyrays Ltd | Information & communication | 2026 |
| Sharab Solutions Ltd | Wholesale & retail | 2025 |
| Sharedbrick Holding Ltd | Real estate | 2025 |
| Sharestep Property Management Limited | Households | 1991 |
| Sharing Good Family Items Limited | Wholesale & retail | 2025 |
| Sharla's Hair Limited | Other services | 2023 |
| Sharmans Agronomy Ltd | Agriculture & fishing | 2023 |
| Sharp Landworks Ltd | Administrative & support | 2025 |
| Sharp Shooters FC Cambridge Ltd | Arts & recreation | 2023 |
| Shaun Thomas Plumbing Heating and Electrical Limited | Construction | 2020 |
| Shaw Capital Management Limited | Real estate | 2023 |
| Shazand Enterprises Limited | Professional & scientific | 2014 |
| Shear Cambridge Limited | Manufacturing | 2003 |
| Shearing's Upholstery and Furnishings Limited | Other services | 2014 |
| Sheehan Designs Limited | Professional & scientific | 2021 |
| Sheepshead ROW Management Limited | Real estate | 2003 |
| Sheet Metal RO Ltd | Manufacturing | 2024 |
| Shefmore Limited | Other services | 1982 |
| Sheikh Imam Cultural Club Limited | Education | 2026 |
| Sheikh Taher AL Zawi Organisation Ltd | Health & social care | 2024 |
| Shelford Heating Limited | Construction | 2011 |
| Shelford Investments Holdings Ltd | Financial services | 2018 |
| Shelford Investments Limited | Real estate | 1979 |
| Shelford Lodge Limited | Hospitality | 1997 |
| Shelford Properties Limited | Construction | 1991 |
| Shelford Rugby Ltd | Arts & recreation | 2011 |
| Shelford Shopfitting Limited | Construction | 1968 |
| Shelford Spice Takeaway Ltd | Hospitality | 2024 |
| Shelford Tree Service Ltd | Agriculture & fishing | 2020 |
| Shelford Woodlands Properties Limited | Households | 1957 |
| Shell Tech Holdings Limited | Information & communication | 2026 |
| Shenchang Invest Co., Limited | Water & waste | 2025 |
| Shengbida Trading Co., Ltd | Wholesale & retail | 2020 |
| Shenghong Ltd | Wholesale & retail | 2025 |
| Shengju Culture Media Co., Limited | Professional & scientific | 2025 |
| Shengxin Import and Export Co., Ltd | Wholesale & retail | 2024 |
| Shennong Benshen Green Farmer (UK) Agriculture Co., Ltd | Agriculture & fishing | 2026 |
| Shenzhen EKI Lighting Industrial Co., Limited | Manufacturing | 2021 |
| Shenzhen Giantfar Technology Co., Limited | Wholesale & retail | 2025 |
| Shenzhen Jieruicc Technology Limited | Wholesale & retail | 2024 |
| Shenzhen Jingangyuan Trading Co., Ltd | Extraterritorial | 2020 |
| Shenzhen Ming TAI NUO KE Electronics Co., Ltd | Manufacturing | 2024 |
| Shenzhen Toplink Technology Co., Ltd | Wholesale & retail | 2023 |
| Shepherdess Walk Management Limited | Real estate | 2013 |
| Sher Private Hire Ltd | Transport & logistics | 2023 |
| Sher Properties Limited | Real estate | 2021 |
| Sher Source Deals Ltd | Administrative & support | 2026 |