| Penny Anderson Associates Limited | Professional & scientific | 2001 |
| Persona Logistics Ltd | Transport & logistics | 2026 |
| Perspectives-Digital Ltd | Information & communication | 2025 |
| Peter Lawrence Estates Ltd | Real estate | 2016 |
| Peter Rigley Limited | Hospitality | 2006 |
| Phil Heler Limited | Health & social care | 2007 |
| Pick Olive Ltd | Hospitality | 2025 |
| Picto Studios Ltd | Professional & scientific | 2009 |
| Pictureland Limited | Extraterritorial | 1998 |
| PIG and Pepper Ltd | Wholesale & retail | 2017 |
| Pimmys Activity Service Limited | Health & social care | 2025 |
| Pinc Creative College | Education | 2024 |
| Pinc Education Group Ltd | Education | 2024 |
| Pinc Education Ltd | Education | 2019 |
| Pinc Exams Ltd | Education | 2024 |
| Pinc Futures Ltd | Education | 2024 |
| Pinc Woodlands College | Education | 2024 |
| Pink Nails and Spa Buxton Ltd | Other services | 2024 |
| Pinnachi Limited | Administrative & support | 2023 |
| Pitter Patter Pet Care Ltd | Extraterritorial | 2025 |
| Pitts Limited | Information & communication | 2019 |
| Plan B Accounting Ltd | Professional & scientific | 2014 |
| PLAN360 Limited | Professional & scientific | 2022 |
| Planet Bollywood Restaurant Limited | Hospitality | 2025 |
| Plasma Biotal Limited | Health & social care | 1990 |
| Play House Buxton Ltd | Wholesale & retail | 2025 |
| PM Control Services Ltd | Other services | 2020 |
| Pocket People Studio Ltd | Professional & scientific | 2025 |
| Pointer Financial Services Limited | Financial services | 2011 |
| Polka Plant Hire Ltd | Manufacturing | 2014 |
| Pork Chop Limited | Real estate | 1999 |
| Porters of Leek Ltd | Other services | 2023 |
| Poynton Horticultural and Agricultural Society | Arts & recreation | 2006 |
| Precision Engineering Services (Buxton) Ltd | Manufacturing | 2010 |
| Precision With Design Limited | Construction | 2009 |
| Premier Eaves (Yorkshire) Limited | Real estate | 2026 |
| Preston Street Holdings Limited | Administrative & support | 2016 |
| Primal Unleashed Music Ltd | Information & communication | 2026 |
| Prime Pharma Services Limited | Professional & scientific | 2010 |
| Printexpress Print & Copy Centre (Buxton) Limited | Manufacturing | 1998 |
| Privilside Property Co.Limited | Households | 1964 |
| Proactive Project Consulting Limited | Information & communication | 2015 |
| Process Control Services UK Ltd | Construction | 1997 |
| Professional Finishing Limited | Professional & scientific | 2000 |
| Project Air Ltd | Information & communication | 2021 |
| Project Equilibrium CIC | Health & social care | 2024 |
| Prolabels Limited | Wholesale & retail | 2013 |
| Protop Smart Solutions Limited | Information & communication | 2020 |
| PT Corner Ltd | Arts & recreation | 2017 |
| Pukka Polymers Limited | Professional & scientific | 2018 |
| Puma Business Services Limited | Professional & scientific | 2025 |
| Punchbowl Park Limited | Hospitality | 2004 |
| Pure Ikonic Ltd | Wholesale & retail | 2025 |
| Purple Umbrella Training Limited | Professional & scientific | 2016 |
| Pursglove Endeavour Limited | Hospitality | 1999 |
| PW Hope 2022 Limited | Professional & scientific | 2022 |
| Quadrant Developments (UK) Ltd | Real estate | 2013 |
| Quadrant Developments Management Company Ltd | Households | 2024 |
| R G Morris & SON Limited | Wholesale & retail | 2003 |
| R Hambleton Services Ltd | Financial services | 2022 |
| R Hill Electrical Services Limited | Manufacturing | 2015 |
| R M Rogers Limited | Extraterritorial | 2005 |
| R R Andrew Limited | Transport & logistics | 2011 |
| R.O. Construction Limited | Construction | 2012 |
| R8TED Electrotech Ltd | Information & communication | 2018 |
| Railside Services Ltd | Construction | 2021 |
| Ramon Marin Ltd | Professional & scientific | 2022 |
| Rawtastic Foods Limited | Wholesale & retail | 2025 |
| Razor Edge Films Limited | Information & communication | 2013 |
| RBB Media Ltd | Information & communication | 2021 |
| Reach Catering Services Ltd | Hospitality | 2011 |
| Read & Turner (Transport) Limited | Wholesale & retail | 1972 |
| Rebel Drinks Ltd | Wholesale & retail | 2020 |
| Red Light Broadcast Limited | Information & communication | 2020 |
| Redfern Site Solutions Ltd | Construction | 2026 |
| Redtread International Limited | Transport & logistics | 2016 |
| Redtread Limited | Wholesale & retail | 2025 |
| Reece Cruz Properties Ltd | Real estate | 2021 |
| Relax Holidays Limited | Real estate | 2020 |
| RFS Coaching Limited | Arts & recreation | 2024 |
| Rich Forever Inc Ltd | Hospitality | 2026 |
| Richard Lane Repairs Ltd | Manufacturing | 2021 |
| Rightio Poultry Farm Ltd | Agriculture & fishing | 2021 |
| Rivers Creative Services Ltd. | Professional & scientific | 2017 |
| RJ Andow Dampproofing Ltd | Construction | 2012 |
| RLT Ltd | Transport & logistics | 1999 |
| RM Hadfield Haulage Limited | Transport & logistics | 2008 |
| RM Hadfield Holdings Limited | Transport & logistics | 2020 |
| RNW Events Limited | Arts & recreation | 2023 |
| Roaches Trading Company Limited | Extraterritorial | 2018 |
| Roar Education Ltd | Education | 2025 |
| ROB Keeling Plumbing and Heating Limited | Construction | 2026 |
| Robert W Dyson LLP | | 2012 |
| Roberts in Ashford Limited | Wholesale & retail | 2014 |
| Robot Paint Ltd | Information & communication | 2023 |
| Robson Blinds Ltd | Wholesale & retail | 2024 |
| Rolling Stock Engineering Solutions Ltd | Professional & scientific | 2019 |
| Roman Design Solutions Limited | Professional & scientific | 2015 |
| Romanian Adventure Limited | Hospitality | 2002 |
| Rooms @ the Vault Limited | Hospitality | 2026 |