| Street Solutions UK Holdings Limited | Financial services | 2024 |
| Street Solutions UK Ltd | Manufacturing | 2019 |
| Streetlight Productions Ltd | Wholesale & retail | 2020 |
| Stressfreecarrental.Com Ltd | Extraterritorial | 2019 |
| Stretford Marine Services Ltd | Manufacturing | 2010 |
| Strongorigin Limited | Information & communication | 2021 |
| Struth Properties Limited | Real estate | 2021 |
| Stubbins Storage Limited | Transport & logistics | 2013 |
| Studentsfirstuk Admissions Ltd | Education | 2022 |
| Studentsfirstuk Ltd | Education | 2021 |
| Studio 30 Tanning & Beauty Limited | Other services | 2016 |
| Studio Fades Ltd | Other services | 2023 |
| Studio Gross + Walker Ltd | Professional & scientific | 2026 |
| Studio Rennaisance Limited | Other services | 2002 |
| Stueken UK Limited | Professional & scientific | 2015 |
| Stuff 4 U Ltd | Wholesale & retail | 2024 |
| Stuff Crust Limited | Hospitality | 2019 |
| Sturdy Sittings Ltd | Wholesale & retail | 2022 |
| STW MED HR Ltd | Health & social care | 2022 |
| Style IT UP Ltd | Wholesale & retail | 2016 |
| Style Trove Ltd | Wholesale & retail | 2025 |
| Style.Me Hair and Beauty Ltd | Other services | 2018 |
| Stylezine Limited | Wholesale & retail | 2023 |
| Stylish Home Renovations (Manchester) Limited | Construction | 2018 |
| SUBHAN786 Ltd | Wholesale & retail | 2021 |
| Subterra Civils Ltd | Financial services | 2025 |
| Sudtec Energy Ltd | Construction | 2025 |
| SUE Hanley Interiors Limited | Construction | 2004 |
| Suicide Bereavement UK Ltd | Other services | 2016 |
| Sulaco Systems Limited | Information & communication | 2019 |
| Sulayman Logistics Ltd | Transport & logistics | 2026 |
| Sulfima Limited | Wholesale & retail | 2025 |
| Suliman Trading Limited | Hospitality | 2017 |
| Sultania's Properties Limited | Real estate | 2021 |
| Sumayyah Holdings Ltd | Financial services | 2026 |
| Summer 2020 Limited | Hospitality | 2020 |
| Summer Lettings Ltd | Real estate | 2019 |
| Summermere Ltd. | Administrative & support | 2015 |
| Summerseat Physiotherapy Clinic Limited | Health & social care | 2014 |
| Summerseat Players Limited | Arts & recreation | 1990 |
| Summerseat Supply Chain Consulting Ltd | Professional & scientific | 2025 |
| Summitsure Limited | Professional & scientific | 2026 |
| Sunday Machine Ltd | Wholesale & retail | 2019 |
| Sunner & Sunner Limited | Wholesale & retail | 2000 |
| Sunny Bower Developments Limited | Real estate | 2025 |
| Sunny Pizza Ltd | Hospitality | 2022 |
| Sunny Stop Inn Ltd | Hospitality | 2018 |
| Sunnywood Estates Limited | Construction | 2004 |
| Sunrise Caribbean Production Ltd | Manufacturing | 2024 |
| Sunrise Caribbean Retail Ltd | Hospitality | 2024 |
| Sunrise Streetz Ltd | Hospitality | 2021 |
| Supatech Limited | Wholesale & retail | 2017 |
| Super Bargains GBR Ltd | Wholesale & retail | 2024 |
| Super Hand Car Wash Bury Limited | Other services | 2017 |
| Super Step Shoes Ltd | Wholesale & retail | 2017 |
| Superdry Damp-Proofing Limited | Construction | 2014 |
| Superdry Flood Restoration Ltd | Professional & scientific | 2020 |
| Superdry Restoration UK Limited | Real estate | 2022 |
| Superior Care Services Limited | Health & social care | 2025 |
| Superior Recruitment Limited | Professional & scientific | 2011 |
| Superior Signs Limited | Manufacturing | 1973 |
| Supersonic MCR Limited | Arts & recreation | 2023 |
| SUPERSTORE786 Limited | Wholesale & retail | 2024 |
| Supertech UK Ltd Ltd | Wholesale & retail | 2013 |
| Suplementtus Ltd | Wholesale & retail | 2019 |
| Supplies UK Ltd | Wholesale & retail | 2022 |
| Support for Independence (North West) Ltd | Health & social care | 2018 |
| Supporting Sisters CIC | Other services | 2021 |
| Supreme Windows (NW) Limited | Construction | 2025 |
| Sure Buy Housing Ltd | Real estate | 2025 |
| Sure Connect Maintenance Ltd | Manufacturing | 2022 |
| Sure Start Motors Limited | Wholesale & retail | 2003 |
| Sure Success Limited | Financial services | 2026 |
| Sure Training Limited | Education | 2012 |
| Sure-Thing Property Investments Ltd | Real estate | 2022 |
| Sure-Thing Property LLP | | 2022 |
| Surface Protection Coatings Holdings Limited | Financial services | 2021 |
| Surgical Sports Solutions Ltd | Health & social care | 2015 |
| Sushi Robots UK Limited | Manufacturing | 2020 |
| Sustainable Innovation and Developments Ltd | Professional & scientific | 2020 |
| Suthers Comfort Ltd | Real estate | 2023 |
| Suzegold Limited | Arts & recreation | 2014 |
| SVA Global Ventures Limited | Professional & scientific | 2016 |
| Swan Financial Advice Ltd | Financial services | 2022 |
| SWC Advisory Limited | Professional & scientific | 2026 |
| Sweat U.K. Ltd | Other services | 2026 |
| Sweet & Toasted Ltd | Hospitality | 2025 |
| Sweet and Savoury Patisserie Ltd | Hospitality | 2021 |
| Sweet Baby Jayne Ltd | Wholesale & retail | 2018 |
| Sweet FA Group Limited | Extraterritorial | 2025 |
| Sweet Home Bargain Ltd | Wholesale & retail | 2025 |
| Sweet Promise Ltd | Health & social care | 2022 |
| Sweet Treats NW Ltd | Wholesale & retail | 2024 |
| SWH NW Ltd | Construction | 2021 |
| Swift Clinical Solutions Ltd | Public administration | 2021 |
| Swiftlaunch Limited | Wholesale & retail | 2025 |
| Swim Steps Swim School Ltd | Education | 2024 |
| Swimmingly Limited | Arts & recreation | 2018 |
| Swings & Smiles (UK) Ltd | Arts & recreation | 2008 |
| Swirlz Bury Limited | Hospitality | 2026 |