| Roman Financial Services Limited | Financial services | 2016 |
| Rome Care Services Ltd | Administrative & support | 2016 |
| Romero Catholic Academy Trust | Education | 2019 |
| Roof and Drive Revive Ltd | Construction | 2025 |
| Roofix Roofing and Building Contractors Ltd | Construction | 2020 |
| ROOM2ROOM Solutions Ltd | Construction | 2025 |
| ROOM365 Limited | Construction | 2020 |
| Root Fifty Two Limited | Professional & scientific | 2008 |
| Rose George Lettings Ltd | Real estate | 2025 |
| Rose Hill Supermarket Ltd | Wholesale & retail | 2026 |
| Rose Marinel Ltd | Other services | 2019 |
| Rose Valley Vets Ltd | Professional & scientific | 2020 |
| Rosedale House Developments Ltd | Construction | 2024 |
| Rosegrove Bangla Ltd | Hospitality | 2023 |
| Rosegrove OUT of School Club Limited | Education | 2007 |
| Rosehill Hotel Limited | Hospitality | 2024 |
| Rosehill NW Limited | Real estate | 2023 |
| Rosewood Electrical Contractors Ltd | Construction | 2013 |
| Rosy Robin Trading Limited | Wholesale & retail | 2022 |
| Rosynx Ltd | Wholesale & retail | 2025 |
| Rothcare Builders Limited | Construction | 2019 |
| Rotherham Plastering Limited | Construction | 2008 |
| Round Frame Ltd | Wholesale & retail | 2021 |
| Rovert Electrical Ltd | Manufacturing | 2006 |
| Rowlec Properties Limited | Real estate | 2018 |
| Royle Chesterman Limited | Wholesale & retail | 2024 |
| Royle International 2000 Limited | Wholesale & retail | 1998 |
| Royle International Foods Limited | Wholesale & retail | 1989 |
| Royle International Snacks & Drinks Limited | Wholesale & retail | 1982 |
| RPB 85 Ltd | Financial services | 2022 |
| RPC Group Holdings Ltd | Financial services | 2023 |
| RPC Properties Ltd | Real estate | 2023 |
| RPC Services Ltd | Real estate | 2003 |
| RRJ Engineering Ltd | Manufacturing | 2024 |
| RS Hire Car Limited | Transport & logistics | 2020 |
| RSE Holdings Limited | Professional & scientific | 2015 |
| RSG Fabrications Ltd | Manufacturing | 2024 |
| RSI Lighting Limited | Construction | 2016 |
| RSR Revolution Ltd | Information & communication | 2024 |
| RT Commercials (NW) Ltd | Real estate | 2023 |
| RT Plumbers Ltd | Construction | 2025 |
| RT Translations Limited | Professional & scientific | 2003 |
| RT8 Investments Limited | Real estate | 2020 |
| RT8 Legal Limited | Professional & scientific | 2009 |
| RT8 LLP | | 2009 |
| RTB Services Limited | Hospitality | 2025 |
| RTC Safety Surfaces Holdings Limited | Financial services | 2015 |
| Ruach Designs Ltd | Wholesale & retail | 1994 |
| Ruba Limited | Hospitality | 2017 |
| Ruben Creative Limited | Professional & scientific | 2017 |
| Runjmc Limited | Arts & recreation | 2021 |
| Runmagic Limited | Hospitality | 1988 |
| Rural London Ltd | Wholesale & retail | 2025 |
| Rushton Heyworth Chartered Construction Management & Surveyors Ltd | Professional & scientific | 2021 |
| Ruth Clarke Ltd | Professional & scientific | 2019 |
| RV Pure Clean Ltd | Administrative & support | 2019 |
| RV Venetian Plaster Ltd | Wholesale & retail | 2026 |
| RW Property Partners Ltd | Real estate | 2025 |
| RWS Contractors Ltd | Construction | 2005 |
| Ryka G Ltd | Real estate | 2025 |
| S & H Soccer Ltd | Arts & recreation | 2020 |
| S & S Halal Meat Ltd | Wholesale & retail | 2026 |
| S a Rentals (NW) Ltd | Real estate | 2021 |
| S and F Properties NW Ltd | Real estate | 2025 |
| S C Precast Limited | Construction | 2019 |
| S Duddy Limited | Construction | 2004 |
| S M Business Solutions Ltd | Financial services | 2021 |
| S Riley Fabrications Ltd | Manufacturing | 2002 |
| S Riley Farms Limited | Agriculture & fishing | 2023 |
| S S H Pharma Limited | Health & social care | 2025 |
| S W TV Lighting Ltd | Construction | 2021 |
| S Walton Wealth Ltd | Professional & scientific | 2024 |
| S&T1 Ltd | Transport & logistics | 2021 |
| S&V Drycleaners Ltd | Other services | 2026 |
| S.D.W. Window Cleaning Services Ltd | Administrative & support | 2020 |
| S.I.R Lancashire Limited | Other services | 2016 |
| S.I.S - Strength in Struggles CIC | Health & social care | 2023 |
| S.V. Holdings Ltd | Real estate | 2026 |
| S.W. Electrical Repairs Limited | Manufacturing | 1999 |
| S.Whitford & Sons Limited | Administrative & support | 1958 |
| S2S Computers Limited | Information & communication | 2004 |
| S4S Graphics Ltd | Professional & scientific | 2016 |
| SA Finance Solutions Limited | Professional & scientific | 2026 |
| SA Financial Solutions Limited | Professional & scientific | 2026 |
| SA Motor Trader Limited | Wholesale & retail | 2025 |
| Saad Car Sales Limited | Wholesale & retail | 2025 |
| SAB Property 1 Ltd | Real estate | 2025 |
| Sabahat Khan Ltd | Wholesale & retail | 2024 |
| Sacrum Limited | Financial services | 2024 |
| Sadia Investments Ltd | Real estate | 2018 |
| Safenet Domestic Abuse and Support Services Ltd | Health & social care | 1999 |
| Safeturn Driving School Limited | Education | 2026 |
| Safety Patrol Ltd | Administrative & support | 2025 |
| Safetynet (UK) Limited | Health & social care | 2003 |
| Sagiri Food Ltd | Hospitality | 2025 |
| Sahab Corporation Limited | Wholesale & retail | 2025 |
| Sal's Desserts Bar Limited | Hospitality | 2024 |
| Sales Connect International Ltd | Information & communication | 2023 |
| Salford Super Market Ltd | Wholesale & retail | 2013 |
| Salono Group Ltd | Information & communication | 2026 |