| Ellington Capital Ventures Limited | Financial services | 2025 |
| Ellington Portfolio Limited | Real estate | 2025 |
| Elliott-Fm Limited | Real estate | 2018 |
| Ellmac Properties Limited | Real estate | 2016 |
| Elmfield Financial Planning Limited | Financial services | 2003 |
| Eluceda Group Limited | Professional & scientific | 2022 |
| Eluceda Limited | Professional & scientific | 2009 |
| Elysian Kitchens & Doors Ltd | Manufacturing | 2020 |
| Elyz Ltd | Wholesale & retail | 2025 |
| EM B2BEM Ltd | Manufacturing | 2023 |
| EMA (Hull) Limited | Hospitality | 2023 |
| Emailgeeks Ltd | Information & communication | 2019 |
| Embery Engineering Ltd | Manufacturing | 2015 |
| Emerald Wellbeing C.I.C. | Health & social care | 2019 |
| EMF Electrical Engineering Ltd | Construction | 2023 |
| Eminence Transport Limited | Wholesale & retail | 2015 |
| EMM Furniture Ltd | Manufacturing | 2024 |
| Emmett and Co (Nelson) Limited | Professional & scientific | 2005 |
| Emmie Clinic Ltd | Other services | 2026 |
| Empire Construction GRP Ltd | Construction | 2024 |
| Empire Construction Team Ltd | Construction | 2021 |
| Empire Electrical Services North West Ltd | Construction | 2025 |
| Empire Estates Properties Limited | Real estate | 2017 |
| Empire News Limited | Wholesale & retail | 2016 |
| Endless Beauty Ltd | Other services | 2022 |
| Endlesss Ltd | Administrative & support | 2017 |
| Energize Dance & Fitness Limited | Education | 2003 |
| Energy Finder Limited | Professional & scientific | 2014 |
| Energy Junction Auditing Ltd | Real estate | 2020 |
| ENERGY4U Limited | Other services | 2019 |
| Energysmart Carbon Ltd | Construction | 2020 |
| Engage Sales Management Services Limited | Professional & scientific | 2022 |
| Engineering Connect Ltd | Administrative & support | 2019 |
| Engineering Design Simonstone Ltd | Professional & scientific | 2025 |
| Engineering Pipework Ltd | Energy | 2014 |
| Engineering Precision Ltd | Manufacturing | 2026 |
| Engledene Limited | Financial services | 2017 |
| Enigma Hairdressing Limited | Other services | 2015 |
| Enrich Developments Ltd | Construction | 2024 |
| Enrolify Ltd | Information & communication | 2025 |
| Enso Creative Arts CIC | Arts & recreation | 2023 |
| Enterprising Habits Ltd | Hospitality | 2020 |
| Entropy Clothing Limited | Wholesale & retail | 2025 |
| Entwistle Enterprises Ltd | Information & communication | 2019 |
| Environmental Construction Services Ltd | Construction | 2022 |
| Enzo Parma Limited | Wholesale & retail | 2023 |
| Enzo Steel Ltd | Construction | 2022 |
| EPB Property Limited | Households | 2016 |
| EPC Local (Burnley) Ltd | Real estate | 2017 |
| Equas Capital Ltd | Financial services | 2025 |
| Equas Holdings Ltd | Financial services | 2026 |
| Equestrian Services Limited | Water & waste | 2025 |
| Equestrian Surfaces Limited | Construction | 1986 |
| Equine Outlet Limited | Wholesale & retail | 2017 |
| Eraa (U.K.) Limited | Manufacturing | 1987 |
| ERC Scrap Metal Ltd | Wholesale & retail | 2018 |
| Ernie’S Floral Design Ltd | Wholesale & retail | 2026 |
| Eryx Invest Limited | Real estate | 2022 |
| ES Contracting Services Limited | Professional & scientific | 2020 |
| Es.Seqally Bodyshop Ltd | Wholesale & retail | 2023 |
| Escape (Barrowford) Limited | Health & social care | 2012 |
| Escape Hair and Beauty (Burnley) Ltd | Other services | 2023 |
| Especially for YOU (NW) Limited | Wholesale & retail | 2019 |
| Especially for YOU Limited | Administrative & support | 2006 |
| Essential Food Hygiene Limited | Hospitality | 2020 |
| Essere.Therapies Ltd | Other services | 2017 |
| Estuary Banks Management Company Limited | Extraterritorial | 2012 |
| ET Home Comfort Limited | Manufacturing | 2026 |
| Eterna AI Solutions Ltd | Professional & scientific | 2025 |
| Eterna Glow Limited | Other services | 2025 |
| Eternal Bell Ltd | Information & communication | 2025 |
| Ethical AZ Ltd | Wholesale & retail | 2025 |
| Euchina Trade Ltd | Wholesale & retail | 2022 |
| Euritas Search Ltd | Administrative & support | 2014 |
| Euro Landmark 3 Limited | Extraterritorial | 2016 |
| Euro-Tran Despatch Limited | Transport & logistics | 2008 |
| Euro.Sdb Limited | Transport & logistics | 2007 |
| Evergreen Blinds Limited | Manufacturing | 2019 |
| Everitt Construction Ltd | Construction | 2023 |
| Everitt Consulting Services Ltd | Professional & scientific | 2024 |
| Everitt Rentals Limited | Real estate | 2025 |
| Everlast Kitchens & Bedrooms Limited | Manufacturing | 2018 |
| Everybuild Ltd | Construction | 2024 |
| Evidale Consulting Limited | Transport & logistics | 1998 |
| Evinda Services Ltd | Financial services | 2023 |
| Evoke Home (Nelson) Ltd | Wholesale & retail | 2025 |
| Evolution Marketing (UK) Ltd | Professional & scientific | 2012 |
| Evolution Pedals Ltd | Manufacturing | 2025 |
| Evolve Software Consultancy Limited | Information & communication | 2013 |
| Exact Procurement Solutions Ltd | Professional & scientific | 2019 |
| Excalibur Web Support Limited | Information & communication | 2000 |
| Excel Travels & Tourism Limited | Administrative & support | 2015 |
| Excellence House Limited | Education | 2022 |
| Excelsa Cleaning Limited | Administrative & support | 2024 |
| Excelsior Properties Ltd | Real estate | 2025 |
| Excite Hub Ltd | Wholesale & retail | 2019 |
| Excotek Ltd | Information & communication | 2014 |
| EXE Transport Limited | Administrative & support | 2025 |
| Exhaultise Limited | Professional & scientific | 2024 |
| Experience Energy UK Ltd | Wholesale & retail | 2014 |