| Empresa Comercial Limited | Real estate | 2008 |
| Emr-Namnews Limited | Administrative & support | 1996 |
| Energy Storage Specialists Ltd | Other services | 2020 |
| Enes Groundworks and Landscaping Ltd | Administrative & support | 2025 |
| Engenuity Limited | Information & communication | 1993 |
| Enhance by Katie Limited | Other services | 2024 |
| Enjoy Irresponsibly Events Ltd | Arts & recreation | 2025 |
| Entertainment 8 Limited | Wholesale & retail | 2021 |
| Entertainment Travel Limited | Arts & recreation | 2010 |
| Entreprise Travel Services Ltd | Transport & logistics | 2018 |
| Enviromap Limited | Households | 2019 |
| Enzo's Aviation Ltd | Administrative & support | 2026 |
| EPC Wheelchairs Ltd | Wholesale & retail | 2017 |
| Epic Icons Limited | Extraterritorial | 2003 |
| Epictetus Solutions Limited | Information & communication | 2023 |
| ER Productions Ltd | Arts & recreation | 2025 |
| Erskine Management Company Limited | Households | 2016 |
| Es&Cons Rail Ltd | Professional & scientific | 2025 |
| Essentialgroup Ltd. | Wholesale & retail | 2011 |
| Estatesearch Group Limited | Professional & scientific | 2024 |
| Estatesearch Limited | Information & communication | 2015 |
| Estatesearch Property Limited | Information & communication | 2025 |
| Estatesure Limited | Information & communication | 2020 |
| Estatetrace Limited | Information & communication | 2023 |
| Etops (AS) UK Limited | Professional & scientific | 2013 |
| Euroline Traders Ltd | Financial services | 2016 |
| Event Childcare Ltd | Other services | 2012 |
| Eventus Executive Search & Selection Limited | Administrative & support | 2024 |
| Eventus Supply Limited | Arts & recreation | 2024 |
| Ever Resin Limited | Construction | 2024 |
| Everson Steel Erectors Ltd | Construction | 2025 |
| Everything Swim Limited | Wholesale & retail | 2017 |
| Evio Consulting Limited | Professional & scientific | 2023 |
| Evloso Pools Ltd | Construction | 2023 |
| Evolucion Ltd | Other services | 2016 |
| EWB Consultancy Ltd | Professional & scientific | 2025 |
| Excel Airport Taxis Ltd | Transport & logistics | 2019 |
| Explorehers Limited | Administrative & support | 2025 |
| Extra Virgin Honey Ltd. | Agriculture & fishing | 2021 |
| F&H Healthcare Limited | Health & social care | 2011 |
| F4F First 4 Frozen Ltd | Wholesale & retail | 2015 |
| FAB Ace Limited | Health & social care | 2019 |
| FAB Mobility Ltd | Transport & logistics | 2020 |
| Fairford Construction Limited | Construction | 2023 |
| Fairhall Services Limited | Administrative & support | 2022 |
| Fairplace Garage Ltd | Wholesale & retail | 2015 |
| Fairplace Holdings Ltd | Real estate | 2024 |
| Fairways Secretaries Limited | Administrative & support | 2015 |
| Falcon Land and Planning Ltd | Professional & scientific | 2023 |
| Family Chiro Ltd | Health & social care | 2023 |
| Fangle Ltd | Real estate | 2008 |
| Farnham Signs Limited | Manufacturing | 2019 |
| Farrahmax Developments Limited | Real estate | 2026 |
| Fatchair Ltd | Professional & scientific | 2012 |
| Feel Happy Limited | Information & communication | 2017 |
| Fell YAT Pastures Limited | Professional & scientific | 2013 |
| Felt Creative Limited | Real estate | 2024 |
| Ferguson Direct Ltd | Manufacturing | 2024 |
| Fernai Ltd | Information & communication | 2026 |
| Fernandia Ltd | Information & communication | 2018 |
| Fetishease Ltd | Health & social care | 2024 |
| FG Electrical Contractors Limited | Construction | 2026 |
| Fibreglass Installations UK Ltd | Construction | 2025 |
| FIG and Flower Ltd | Other services | 2025 |
| FIG POP Shop Ltd | Wholesale & retail | 2019 |
| Film Crew Collective Network Limited | Information & communication | 2011 |
| Film Fixture Lighting Limited | Administrative & support | 2022 |
| Filter Screen Supply Limited | Manufacturing | 1987 |
| Finance Partners (South East) Limited | Professional & scientific | 2024 |
| Firbank Homes Ltd | Construction | 1985 |
| First Foot Clinic (Sussex) Limited | Health & social care | 2011 |
| Fitii Ltd | Information & communication | 2015 |
| Five the Boulevard Management Company Ltd | Households | 2014 |
| Flanco Limited | Hospitality | 2022 |
| Flesher Services Limited | Professional & scientific | 2019 |
| Fletcher's Sussex Ltd | Administrative & support | 2025 |
| Flexen Care Ltd | Professional & scientific | 2023 |
| Flickerlee Limited | Wholesale & retail | 2018 |
| Flight SIM Technologies Limited | Information & communication | 2018 |
| Florgen Icare Company Limited | Health & social care | 2022 |
| Flowjump Gloucester Ltd | Hospitality | 2024 |
| Flowjump South Ltd | Hospitality | 2024 |
| Fluid Marketing Consultants Limited | Professional & scientific | 2023 |
| Fluxsports Ltd | Wholesale & retail | 2019 |
| FLY Communications Ltd | Administrative & support | 2014 |
| Flying Colours Fire & Security Systems Ltd | Administrative & support | 2015 |
| Flying Dog Services Ltd | Administrative & support | 2020 |
| Flying Geese Consultancy Limited | Professional & scientific | 2023 |
| Flytrap Film Ltd | Information & communication | 2025 |
| Focused Change Ltd | Professional & scientific | 2022 |
| Folders Lane Management Company Limited | Households | 1999 |
| Follett Care Limited | Health & social care | 1981 |
| Follett Homes Limited | Health & social care | 2025 |
| Fons Networks Limited | Professional & scientific | 2020 |
| Foodmeal Ltd | Hospitality | 2024 |
| Football FUN Factory (Community 073) Limited | Arts & recreation | 2022 |
| Football FUN Factory (Community 080) Limited | Arts & recreation | 2022 |
| Footprints and Dreams Ltd | Administrative & support | 2018 |
| FOR Animals Limited | Wholesale & retail | 1998 |
| Forefront Energy Solutions (UK) Ltd | Professional & scientific | 2013 |