| RJB Motorcycles Ltd | Wholesale & retail | 2016 |
| RKL HU8 0TY Limited | Real estate | 2019 |
| RKL IG1 2ET Ltd | Real estate | 2019 |
| RKL Lettings Limited | Real estate | 2019 |
| RKL Properties Holbeach Ltd | Real estate | 2020 |
| RKL Properties Ltd | Real estate | 2019 |
| RMC PROJECTS2020 Ltd | Professional & scientific | 2018 |
| RMK Healthcare Private Limited | Health & social care | 2011 |
| RMS Technologies UK Ltd | Professional & scientific | 2023 |
| Roadtripping Coffee Ltd | Hospitality | 2024 |
| Roadways Solutions Ltd | Construction | 2021 |
| ROB O'Neill Mortgages Ltd | Financial services | 2015 |
| Robert Day and Company Limited | Administrative & support | 2005 |
| Roche Logistics Specialists Ltd | Transport & logistics | 2021 |
| Rock Coding Ltd | Information & communication | 2017 |
| Rock Executive Development Ltd | Professional & scientific | 2019 |
| Rocks Forever Limited | Administrative & support | 2009 |
| Rocktheatic Ltd | Hospitality | 2021 |
| Rockwood Garden Studios Ltd | Construction | 2016 |
| ROD Facilities Management Ltd | Administrative & support | 2024 |
| Rorfire Plumbing Limited | Construction | 2024 |
| ROSCOE360 Ltd | Professional & scientific | 2018 |
| Rose Racing Fabrications Ltd | Manufacturing | 2017 |
| Rosehill Farms LLP | | 2015 |
| Rosi Ltd | Information & communication | 2023 |
| Roving Healthcare Ltd | Health & social care | 2024 |
| ROY Anthony Joinery Ltd | Manufacturing | 2016 |
| RP Direct Logistics Ltd | Transport & logistics | 2020 |
| RRG Premium Sales Ltd | Wholesale & retail | 2020 |
| RS & RH Network Services Ltd | Information & communication | 2019 |
| RSA Contract Services Ltd | Construction | 2005 |
| RSB Convenience Store Ltd | Wholesale & retail | 2015 |
| Rsbans Ltd | Transport & logistics | 2018 |
| Rubble Trouble Ltd | Administrative & support | 2015 |
| Rubgess Services Ltd | Health & social care | 2020 |
| Rubix Business Services Ltd | Professional & scientific | 2021 |
| Ruby Hook Limited | Other services | 2019 |
| Rushmere Helicopters LLP | | 2008 |
| Russell & Butler (Sales) Limited | Real estate | 2019 |
| Rusty PIG Consulting Ltd | Administrative & support | 2016 |
| RV Fit Ltd | Wholesale & retail | 2025 |
| Rykirst Construction Ltd | Construction | 2006 |
| S & R Bones Limited | Manufacturing | 1998 |
| S J Humphrey Agricultural Buildings Ltd | Construction | 2009 |
| S Rudd Ltd | Construction | 2026 |
| S&Nr Hodges Company Ltd | Agriculture & fishing | 2022 |
| S&S Church Developments Limited | Real estate | 2025 |
| S. Weingart Roofing Ltd | Construction | 2015 |
| S4A Development Limited | Arts & recreation | 2017 |
| S4A Group Ltd | Education | 2015 |
| S4A Holdings Ltd | Other services | 2023 |
| Saab 1 Ltd | Real estate | 2025 |
| Saab 2 Ltd | Real estate | 2025 |
| Saab 3 Ltd | Real estate | 2025 |
| Saab Capital Ltd | Real estate | 2025 |
| Saab Chester Way Ltd | Real estate | 2025 |
| Saab Eade Road Ltd | Real estate | 2025 |
| Sabris Consulting Limited | Professional & scientific | 2003 |
| Saddlers Court Ltd | Real estate | 2012 |
| Safeguarding Momentum Limited | Professional & scientific | 2011 |
| SAI Sarathy Ltd | Information & communication | 2019 |
| Saint Clare Films Limited | Information & communication | 2011 |
| Sandcastle Builders Ltd | Construction | 1986 |
| Sanders Aviation Consultancy Limited | Wholesale & retail | 2013 |
| Sandpit Farm Limited | Professional & scientific | 2003 |
| Sannathi Limited | Information & communication | 2015 |
| Sarah Brason Brand Amplifier Limited | Professional & scientific | 2019 |
| Sarah Hanlon Coaching Ltd | Other services | 2021 |
| Sass and Grace Bridal Experience Limited | Wholesale & retail | 2015 |
| Saucy Jack and the Space Vixens Originators Limited | Arts & recreation | 1996 |
| Sauldgr Ltd | Other services | 2018 |
| Sauros Limited | Manufacturing | 2007 |
| Savage Adam Ltd | Manufacturing | 2026 |
| SBG Consultants Limited | Other services | 2022 |
| SBS Services for Education Limited | Information & communication | 2020 |
| Schema Studios International Ltd | Administrative & support | 2014 |
| Schreuders Design Ltd | Information & communication | 2011 |
| Scotify Ltd | Professional & scientific | 2024 |
| Screengasm Ltd | Information & communication | 2024 |
| Scuffle Consulting Ltd | Real estate | 2026 |
| Scuffle Ltd | Real estate | 2019 |
| Seathub Pro Limited | Extraterritorial | 2025 |
| Sector One Socials Ltd | Information & communication | 2026 |
| Secure Information Assured Limited | Information & communication | 2017 |
| Sederholm Selected Limited | Arts & recreation | 2013 |
| SEED2SUCCESS Limited | Professional & scientific | 2016 |
| Seekingsolutionsgb Ltd | Real estate | 2019 |
| Selby Studio Ltd | Construction | 2025 |
| Seleqtr Ltd | Information & communication | 2026 |
| Selwyn Studio Ltd | Real estate | 2025 |
| Seven Twentyfour Creative Ltd | Professional & scientific | 2019 |
| SEVENTY7 Laps Limited | Administrative & support | 2014 |
| Sew-It-All Limited | Wholesale & retail | 1991 |
| SFI Consulting Ltd | Professional & scientific | 2024 |
| SH DEC Ltd | Professional & scientific | 2022 |
| Shaheen B&H Ltd | Hospitality | 2026 |
| Shard I.T. Services Ltd | Administrative & support | 2014 |
| Shawcan Energy Solutions Ltd | Construction | 2020 |
| Shelly's Shop UK Ltd | Wholesale & retail | 2021 |
| Shelter ME Housing CIC | Health & social care | 2025 |