| Puremed Aesthetics Ltd | Health & social care | 2011 |
| Purplesectoreng Ltd | Professional & scientific | 2024 |
| PW Curator Ltd | Professional & scientific | 2022 |
| PWT Luxe Ltd | Administrative & support | 2022 |
| QIC Direct Limited | Wholesale & retail | 2017 |
| Qictrims Limited | Manufacturing | 2013 |
| Quercus Forest Products Limited | Wholesale & retail | 2008 |
| Questor Studios Ltd. | Information & communication | 2014 |
| Quicksharp Ltd | Wholesale & retail | 2011 |
| Quintilian Ltd | Professional & scientific | 2018 |
| R & G Catering Limited | Hospitality | 2025 |
| R J White Contracting Limited | Other services | 2026 |
| R V Bennett Limited | Professional & scientific | 1998 |
| R&J Supplies Ltd | Wholesale & retail | 2025 |
| R-T-M Capital Limited | Administrative & support | 2013 |
| R-T-M Landscapes Limited | Administrative & support | 2013 |
| R. H. White Limited | Other services | 1986 |
| R.B.Williams Classic Car and Motor Cycle Transport Limited | Transport & logistics | 2026 |
| R2 Refrigeration Ltd | Wholesale & retail | 2009 |
| R8ER Group Ltd | Financial services | 2022 |
| Racelogic Limited | Manufacturing | 1992 |
| Rackham Film&Tv Ltd | Arts & recreation | 2022 |
| Radcliffe Gower Limited | Professional & scientific | 1993 |
| Radclive Paving Ltd | Administrative & support | 2026 |
| Radford Development Services Ltd | Construction | 2021 |
| Radhe Krishna Motors Limited | Wholesale & retail | 2025 |
| Radicle Landscaping Ltd | Administrative & support | 2025 |
| Rage Exploitation Company Limited | Information & communication | 2025 |
| Rage Productions Ltd | Information & communication | 2025 |
| Railsense Limited | Professional & scientific | 2019 |
| Raspberry Sky Services Limited | Information & communication | 2006 |
| Ratecloud BI Ltd | Administrative & support | 2012 |
| Rather Splendid Ltd | Information & communication | 2026 |
| Rawbe Limited | Construction | 2014 |
| Raza United Properties, Limited | Construction | 2017 |
| RC2050 Ltd | Administrative & support | 2024 |
| RC24 Design Ltd | Manufacturing | 2025 |
| RDB Mortgages Limited | Financial services | 2017 |
| RDK Consultants Limited | Construction | 2017 |
| RDR Technologies Limited | Administrative & support | 2013 |
| Ready for Refurb Ltd | Construction | 2025 |
| Readylinks Limited | Transport & logistics | 2026 |
| Real Mccoy Investments Ltd | Real estate | 2025 |
| Reality Training Limited | Information & communication | 2000 |
| Really Cool Projects Limited | Wholesale & retail | 2021 |
| Recoverease Ltd | Professional & scientific | 2024 |
| Red 4 Design Projects Limited | Professional & scientific | 2007 |
| Red Barn Hair Ltd | Other services | 2012 |
| Red EGG Consulting Ltd | Information & communication | 2023 |
| Red ELM Construction Limited | Construction | 2013 |
| Red EYE Events (International) Ltd | Administrative & support | 2017 |
| Red EYE Events Limited | Administrative & support | 2008 |
| Red Hart Advisory Ltd | Professional & scientific | 2025 |
| Red KAT Ltd | Professional & scientific | 2023 |
| Red Kite Motors Limited | Wholesale & retail | 2019 |
| Red Kite Scenic Services Ltd | Information & communication | 2014 |
| Red Kite Training Matters Limited | Education | 2015 |
| Redbird Drone Services Ltd | Professional & scientific | 2023 |
| Redding and Redding Limited | Wholesale & retail | 1996 |
| Redemption Healthcare and Training Limited | Health & social care | 2018 |
| Redfield Construction Limited | Construction | 2002 |
| REDIT20 Ltd | Information & communication | 2025 |
| Redlime Limited | Construction | 1985 |
| Reece Repairs &Maintenance Services Ltd | Construction | 2020 |
| Reflection Anodising Limited | Manufacturing | 2025 |
| Reflection Polishing & Plating Ltd | Manufacturing | 2025 |
| Regional Glass and Maintenance Ltd | Construction | 2024 |
| Reklaw Holdings Limited | Extraterritorial | 2016 |
| Reliance Construction and Facilities Management Ltd | Construction | 2024 |
| Reliance Holdings Ltd | Other services | 2021 |
| Reliance Mechanical Limited | Professional & scientific | 2015 |
| Reliant Specialist Ltd | Construction | 2026 |
| Rely Green Ltd | Manufacturing | 2018 |
| Remstate Limited | Professional & scientific | 2025 |
| Rentatech Ltd | Other services | 2017 |
| Rentto Limited | Real estate | 2020 |
| Research & Development Relief Limited | Extraterritorial | 2011 |
| Research Ready Ltd | Professional & scientific | 2022 |
| Resource Legal Operations Ltd | Professional & scientific | 2026 |
| Restaranations Ltd | Manufacturing | 2019 |
| Resurima Limited | Health & social care | 2014 |
| Retro Gaming Market Limited | Wholesale & retail | 2025 |
| Revel Properties Ltd | Real estate | 2019 |
| Reverifications Limited | Extraterritorial | 2014 |
| Revival Consultants Limited | Professional & scientific | 2018 |
| Revolution Engineering Supplies Limited | Wholesale & retail | 2005 |
| Reynolds Motorsport Management Limited | Arts & recreation | 1995 |
| RGA Buckingham Ltd | Arts & recreation | 2024 |
| Rhino Products (U.K.) Limited | Wholesale & retail | 1996 |
| Rhino's Gym Buckingham Ltd | Arts & recreation | 2023 |
| Richard Goodlad Consulting Services Ltd | Professional & scientific | 2017 |
| Rick's Gym Ltd | Construction | 2025 |
| Rickfords Hill Publishing Ltd. | Wholesale & retail | 2002 |
| Ridgeline Automotive Ltd | Professional & scientific | 2026 |
| Rika Innovations (Bedford) Limited | Hospitality | 2023 |
| Rikke Lohse Ltd | Administrative & support | 2019 |
| Ringwood Services Limited | Wholesale & retail | 2000 |
| RIO Workwear Solutions Limited | Wholesale & retail | 2009 |
| Ripple Africa | Professional & scientific | 2003 |
| Ripple Carbon Limited | Administrative & support | 2022 |