| SUB50 Ltd | Wholesale & retail | 2025 |
| Subcool IT Limited | Information & communication | 2000 |
| Suburban FOX Limited | Real estate | 2014 |
| Suffolk Spine Limited | Health & social care | 2015 |
| Sugarfield Limited | Administrative & support | 1999 |
| Summit Medical Services Ltd | Education | 2025 |
| Sundial Production House Ltd | Arts & recreation | 2019 |
| Sunflower Families CIC | Health & social care | 2023 |
| Sungs Vision Investment UK Ltd | Wholesale & retail | 2025 |
| Sunlight Capital Partners LLP | | 2025 |
| Sunnyside Care Limited | Administrative & support | 2012 |
| Sunrise Heating, Plumbing and Air Conditioning Limited | Construction | 2026 |
| SUP Funk Ltd | Wholesale & retail | 2024 |
| Supablind Limited Liability Partnership | | 2007 |
| Supplement Corner Ltd | Wholesale & retail | 2025 |
| Support Bird Tech Ltd | Wholesale & retail | 2022 |
| Supra D&M LLP | | 2009 |
| Supreme MZ Events Ltd | Hospitality | 2026 |
| Surefoot Homes Ltd | Real estate | 2025 |
| Surface Damage Solutions Ltd | Administrative & support | 2022 |
| Surgery at Maypole Limited | Health & social care | 2020 |
| Surgical EYE Services Limited | Health & social care | 2011 |
| Sustainable Care Limited | Health & social care | 2025 |
| Sustainable Tropical Agriculture Consultancy Limited | Professional & scientific | 2020 |
| Sutherland Leisure Limited | Hospitality | 2016 |
| Sutton Lane House Limited | Households | 1989 |
| Suzie Walker Executive Search Ltd | Administrative & support | 2009 |
| SW TEN Limited | Construction | 2020 |
| Swains Window Makeover Limited | Administrative & support | 2014 |
| Swan Street Coaches Ltd | Transport & logistics | 2003 |
| Swan View Retreats Ltd | Real estate | 2022 |
| Sweat Strong Ltd | Arts & recreation | 2025 |
| Swift Bidco Limited | Financial services | 2025 |
| Swift Midco I Limited | Financial services | 2025 |
| Swift Midco II Limited | Financial services | 2025 |
| Swift Topco Limited | Financial services | 2025 |
| Switched on Digital Ltd | Construction | 2023 |
| Switched on Electrical Installations (Bromsgrove) Limited | Construction | 2019 |
| SWL Group International Ltd | Information & communication | 2014 |
| SWS Trustee Limited | Financial services | 2023 |
| Syfi Ltd | Wholesale & retail | 2023 |
| Sylvanus LLP | | 2015 |
| Symonds & Newey Ltd | Construction | 2015 |
| Sync Site Solutions Limited | Professional & scientific | 2016 |
| Synco Workplace Consultancy Ltd | Wholesale & retail | 2025 |
| Syntagma Flow Ltd | Professional & scientific | 2025 |
| Syntax Systems Limited | Information & communication | 2025 |
| Syntechnologies Limited | Administrative & support | 2009 |
| Syrinx Temple Ltd | Information & communication | 1998 |
| Systemzoo Limited | Professional & scientific | 2014 |
| T & G Utilities Construction Limited | Wholesale & retail | 2009 |
| T & S Pipework Services Limited | Construction | 2001 |
| T & T Vauxhall Services Ltd | Wholesale & retail | 2018 |
| T S Mills Limited | Arts & recreation | 2024 |
| T Sheen Properties Limited | Real estate | 2020 |
| T&J Aspinall Ltd | Real estate | 2023 |
| T&M Projects Ltd | Construction | 2015 |
| T&M Roofing Limited | Construction | 2017 |
| T&M Technology Limited | Information & communication | 2022 |
| T. & M. Garages Limited | Wholesale & retail | 1983 |
| Tackle Growth Ltd | Health & social care | 2024 |
| Taenebra Films Limited | Information & communication | 2015 |
| TAG Design Associates Limited | Professional & scientific | 2023 |
| Tailorations Ltd | Other services | 2023 |
| Tailored Electrical Contractors Ltd | Construction | 2026 |
| Tailored Garden Rooms Ltd | Construction | 2020 |
| Taiyuan Trade Limited | Wholesale & retail | 2026 |
| Takeover Entertainment Ltd | Information & communication | 2022 |
| Talentgapp Ltd | Administrative & support | 2025 |
| Talkswithtoya CIC | Wholesale & retail | 2026 |
| Talmont Properties Ltd | Real estate | 2015 |
| Talpa Properties Limited | Real estate | 2012 |
| Tanki Ltd | Wholesale & retail | 2020 |
| Taprecycle Limited | Water & waste | 2025 |
| Taralyns Marketing LAB Limited | Professional & scientific | 2020 |
| Tardebigge Consultants Limited | Information & communication | 1994 |
| Tardebigge Group Limited | Professional & scientific | 2002 |
| Tardebigge Holdings Limited | Real estate | 1970 |
| Tardebigge New Wharf CIC | Arts & recreation | 2025 |
| Tauromachian Limited | Transport & logistics | 2022 |
| Tawk Network Limited | Information & communication | 2012 |
| Taxes & Accountancy Ltd | Professional & scientific | 2020 |
| Taylor Nash Limited | Administrative & support | 2004 |
| TD Capital Limited | Financial services | 2022 |
| TE Brands Group Ltd | Financial services | 2023 |
| TE Brands Investments Ltd | Real estate | 2023 |
| TE Brands Ltd | Wholesale & retail | 2021 |
| Team HB Holdings Limited | Financial services | 2023 |
| Team Logic Ltd | Wholesale & retail | 2025 |
| Tech.Cad+Cam. Limited | Information & communication | 1988 |
| Techlex Consulting Ltd | Professional & scientific | 2024 |
| Technical Drive Digital Limited | Information & communication | 2019 |
| Technical Drive Limited | Information & communication | 2008 |
| Technique (T.E.R.) Repairs Limited | Administrative & support | 2007 |
| Techsavvi Ltd | Information & communication | 2024 |
| Tectona Forestry Management Limited | Agriculture & fishing | 2018 |
| Teknomat U.K. Limited | Wholesale & retail | 1991 |
| Temchu Limited | Professional & scientific | 2007 |
| Teme Court Limited | Real estate | 2009 |
| Temple Tiggula Holdings Limited | Real estate | 2018 |