| Elmsvyne Developments Limited | Professional & scientific | 2001 |
| Elmsvyne Holdings Limited | Professional & scientific | 2005 |
| Elmsvyne Investments Limited | Construction | 2005 |
| Elmsvyne Leisure Limited | Hospitality | 2005 |
| Elmsvyne Limited | Construction | 1999 |
| Elmsvyne Marine Limited | Professional & scientific | 2005 |
| Elodea Productions Limited | Arts & recreation | 2021 |
| Elsworth Holdings Property Development Ltd | Construction | 2024 |
| Elyron Limited | Wholesale & retail | 2026 |
| Embli Solutions Ltd | Information & communication | 2023 |
| EME Care Central Ltd | Extraterritorial | 2022 |
| Emeltiaar Limited | Information & communication | 2025 |
| Emg-Cad Limited | Construction | 2014 |
| Emma Phillips Limited | Health & social care | 2013 |
| Emma's Angels Limited | Administrative & support | 2026 |
| Emmeline Productions Limited | Information & communication | 2020 |
| Empress Skin Limited | Other services | 2025 |
| Empson Engineering Limited | Manufacturing | 2004 |
| Enable Independent Limited | Financial services | 2002 |
| Encanto Limited | Administrative & support | 2005 |
| Encrypted Events Ltd | Arts & recreation | 2024 |
| Energy Controls Midlands Ltd | Manufacturing | 2025 |
| Energy Transitions Limited | Manufacturing | 2012 |
| Engage, Empower, Enrich CIC | Education | 2024 |
| Engine Reconditioning & Parts Limited | Manufacturing | 1984 |
| English Antique Glass Limited | Manufacturing | 2000 |
| Enigma Car & Commercial Repairs Ltd | Administrative & support | 2009 |
| Ennis Solutions Ltd | Professional & scientific | 2016 |
| Enpedwards Ltd | Health & social care | 2025 |
| Enrich: Your Fitness Ltd | Arts & recreation | 2021 |
| Enterprise Healthcare Solutions Ltd | Health & social care | 2017 |
| Enterprising Insights Limited | Professional & scientific | 2016 |
| Environmental Integrated Solutions Limited | Administrative & support | 2005 |
| Envisage International Film Festival Limited | Information & communication | 2024 |
| Enzipe UK Ltd | Education | 2022 |
| EQS Services Limited | Professional & scientific | 2002 |
| Equinox Solutions Limited | Construction | 2011 |
| Erbium Records Ltd | Arts & recreation | 2020 |
| ES a MUN Services Limited | Professional & scientific | 2023 |
| ESP Thinking Limited | Information & communication | 2016 |
| Espada Store Ltd | Wholesale & retail | 2025 |
| Esperanto Filmoj Limited | Information & communication | 2023 |
| Esperanto Holdings Limited | Information & communication | 2008 |
| Espi Group Limited | Professional & scientific | 2014 |
| Essential Fitting Limited | Administrative & support | 2011 |
| Essential Marketer Limited | Wholesale & retail | 2008 |
| Estate Advisors Ltd | Real estate | 2011 |
| Estria Limited | Professional & scientific | 1996 |
| Ethical First Limited | Professional & scientific | 2004 |
| Ethos Audio Ltd | Administrative & support | 2010 |
| Ettington Grange Management Limited | Households | 1974 |
| Euphoric Holdings Limited | Financial services | 2026 |
| Euphoric Medical Limited | Health & social care | 2026 |
| Euro-Cut Abrasives (G.B.) Limited | Wholesale & retail | 1999 |
| EV Movements Ltd | Transport & logistics | 2024 |
| Evans Boxing & Fitness Ltd | Arts & recreation | 2013 |
| Evans's Cottage Homes | Hospitality | 1868 |
| Event Design and Build Limited | Professional & scientific | 2011 |
| Everett Way Limited | Arts & recreation | 2025 |
| Evergreen (West Midlands) Ltd | Administrative & support | 2001 |
| Evergreen Conservation Group Limited | Construction | 2019 |
| Evergreen Corporate Consultancy Ltd | Agriculture & fishing | 2006 |
| Evergreen Drainage Solutions Limited | Water & waste | 2020 |
| Evergreen General Services Limited | Administrative & support | 2026 |
| Evergreen Group Holdings Limited | Financial services | 2021 |
| Evern Enterprises Ltd | Wholesale & retail | 2025 |
| Evesham Glass and Glazing Limited | Construction | 2013 |
| Evident Site Services Ltd | Wholesale & retail | 2023 |
| Evie SJ Photography Ltd | Professional & scientific | 2025 |
| Evowrap Ltd | Construction | 2020 |
| Excalibre Technologies Ltd | Other services | 2007 |
| Excalibur Engineering Services Ltd | Professional & scientific | 2021 |
| Exchange Capital Limited | Construction | 2014 |
| Excool China Limited | Administrative & support | 2017 |
| Excool Pacific Limited | Energy | 2023 |
| Exhibitions and Events Limited | Administrative & support | 2004 |
| Eximia Vascular Services Ltd | Health & social care | 2021 |
| Eximius Consultancy Limited | Professional & scientific | 2025 |
| Eximius Enterprises Limited | Arts & recreation | 2025 |
| Eximius Sports Limited | Arts & recreation | 2025 |
| EXITS4ALL Ltd | Manufacturing | 2025 |
| Exotic Express Ltd. | Wholesale & retail | 2022 |
| Expedite Business Development Consulting Ltd | Professional & scientific | 2012 |
| Experiential/H Limited | Arts & recreation | 2023 |
| Expert Gym Equipment Ltd | Financial services | 2025 |
| Exploding Phone Limited | Information & communication | 2009 |
| Explora 2026 Ltd | Arts & recreation | 2026 |
| Extend IT Ltd | Construction | 2020 |
| Extension Drawings Ltd | Professional & scientific | 2018 |
| Extragenius Limited | Information & communication | 2008 |
| Extreme Hire Ltd | Administrative & support | 2018 |
| EYE SEE Films Limited | Financial services | 2025 |
| EYE SEE Holdings Limited | Financial services | 2025 |
| Eyespace Eyewear (UK) Limited | Health & social care | 2016 |
| Eyespace Eyewear Limited | Health & social care | 2013 |
| EZE Air Limited | Administrative & support | 2004 |
| F & Y Property Holdings Limited | Real estate | 2024 |
| F J a Design Limited | Health & social care | 2015 |
| F W Lyons (Developers) Limited | Construction | 1959 |
| F.W. Lyons & Sons Limited | Construction | 1959 |