| DDG Property Services Ltd | Real estate | 2025 |
| DE Rohan FIC1 Limited | Financial services | 2023 |
| DEA Worky UK Ltd | Wholesale & retail | 2022 |
| Deal Investments Limited | Real estate | 2020 |
| Dean James Developments Limited | Professional & scientific | 2019 |
| Debt Solve UK Limited | Administrative & support | 2007 |
| Debut Developments Ltd | Professional & scientific | 2007 |
| Decision 1 Limited | Wholesale & retail | 2000 |
| Decor Design Flooring Ltd | Other services | 2019 |
| Deeks Wildlife Solutions Limited | Administrative & support | 2023 |
| Deekshaa CIC | Arts & recreation | 2020 |
| Deep Impact Solutions Limited | Information & communication | 2002 |
| Definitive Conclusions Ltd | Information & communication | 2025 |
| Defy Social Ltd | Professional & scientific | 2021 |
| Dekatria Ltd | Professional & scientific | 2025 |
| Delphic Limited | Information & communication | 2018 |
| Delta Design CAD Services Limited | Professional & scientific | 2009 |
| Deltavale Construction Limited | Construction | 1983 |
| Deluxe Executive Travel Limited | Transport & logistics | 2026 |
| Demolition Solutions Ltd | Water & waste | 2019 |
| Demon Dubs Limited | Wholesale & retail | 2025 |
| Denise Lesley Hair and Beauty Limited | Other services | 2005 |
| Denmark Products Limited | Professional & scientific | 2005 |
| Dennis Hall Management Company Limited | Households | 2004 |
| Dennison Plumbing Limited | Construction | 2015 |
| Dennison Tiling Limited | Construction | 2017 |
| Dermatology Services Solihull Ltd | Health & social care | 2016 |
| Desaine International Limited | Water & waste | 2017 |
| Design by Global Ltd | Information & communication | 2025 |
| Design for Environments Limited | Professional & scientific | 2014 |
| Design IT Landscapes Limited | Administrative & support | 2024 |
| DESIGN4PETS Limited | Wholesale & retail | 2022 |
| Destination High ST Limited | Administrative & support | 2019 |
| Destiny Finance Ltd | Financial services | 2015 |
| Destiny Financial Services Ltd | Professional & scientific | 2004 |
| Destiny Holdings Limited | Financial services | 2018 |
| Destiny Media Group Ltd | Manufacturing | 2022 |
| Developer Connections Ltd | Construction | 2021 |
| Development Design Solutions Ltd | Professional & scientific | 2015 |
| Devil's Chimney Limited | Construction | 2024 |
| Devine Living Limited | Real estate | 2025 |
| Dexshell Limited | Wholesale & retail | 2021 |
| Deyang Motion Limited | Wholesale & retail | 2025 |
| Dfpl Consulting Ltd | Professional & scientific | 2019 |
| DGB Freight Services Limited | Transport & logistics | 2008 |
| DHA Management Limited | Professional & scientific | 1995 |
| DHB Homes Limited | Construction | 2018 |
| DI Luca Investments Limited | Real estate | 2009 |
| DI Luca Limited | Real estate | 2016 |
| Dibynn Enterprise Ltd | Financial services | 2023 |
| Dick's Chicken Shack Ltd. | Hospitality | 2024 |
| Dick's Smokehouse Ltd | Hospitality | 2020 |
| Digital Football Games Ltd | Information & communication | 2022 |
| Digital Hygge Ltd | Administrative & support | 2025 |
| Digital Jane Ltd | Professional & scientific | 2025 |
| Digital Pharaoh U.K Ltd | Manufacturing | 2019 |
| Digitalsolvia Ltd | Wholesale & retail | 2026 |
| Dillon Plastering Limited | Construction | 1999 |
| Dimex Resources Limited | Health & social care | 2023 |
| DIP Property Investments Ltd | Hospitality | 2025 |
| Dipa Business Ltd | Hospitality | 2017 |
| Dirty Duck NW Ltd | Wholesale & retail | 2022 |
| Discounted Bargains Ltd | Wholesale & retail | 2026 |
| Divine Lines Studio Ltd | Other services | 2026 |
| Dixon Financial Solutions Limited | Financial services | 2009 |
| DJ Carpentry & Building Maintenance Limited | Construction | 2018 |
| DJ Corless Entertainment Ltd | Information & communication | 2024 |
| DJC Mechanical Limited | Construction | 2022 |
| Djinn Medical Ltd | Health & social care | 2026 |
| DJO Holdings Ltd | Financial services | 2023 |
| DJO Hvac Services Ltd | Energy | 2025 |
| DJS Roofing Services Ltd | Construction | 2022 |
| DLC Leisure Ltd | Arts & recreation | 2016 |
| DLE Supply Chain Solutions Ltd | Professional & scientific | 2021 |
| DM Automotive Design Limited | Professional & scientific | 2012 |
| DNA Boxing Limited | Other services | 2022 |
| DNA Properties Ltd. | Real estate | 2002 |
| DNA Unique Business Solutions Limited | Information & communication | 1998 |
| DO Moore Orthopaedics Consultancy Limited | Health & social care | 2023 |
| Dobbins Strategy Limited | Information & communication | 2026 |
| Dockside Coffee Bar Ltd | Hospitality | 2025 |
| Doddington Care Ltd | Health & social care | 2016 |
| Doddington Lodge Ltd | Real estate | 2019 |
| Doleman Drilling & Sawing Ltd | Construction | 2023 |
| Dose Hair Limited | Health & social care | 2024 |
| Dove Adolescent Services Limited | Health & social care | 1998 |
| DP Network Limited | Information & communication | 2018 |
| DR Julia SEN Limited | Health & social care | 2017 |
| DR SAN Investments Limited | Health & social care | 2020 |
| DR Sharon Wong Ltd | Health & social care | 2012 |
| Dreamgun Limited | Information & communication | 2023 |
| DRH Property Maintenance Ltd | Construction | 2023 |
| Drinkintime Ltd. | Wholesale & retail | 2003 |
| Droitwich Tyres & Exhaust (Bromsgrove) Limited | Wholesale & retail | 1989 |
| Drop Depot Ltd | Wholesale & retail | 2025 |
| DRS Property Services Ltd | Construction | 2012 |
| DRY Riser Productions Limited | Information & communication | 2021 |
| Dryspy Ltd | Hospitality | 2020 |
| DS Corporate Consulting Limited | Professional & scientific | 2026 |
| DS Electrical Systems Ltd | Construction | 2025 |