| Equitherm Limited | Construction | 2011 |
| Equity Bookkeeping Limited | Professional & scientific | 2017 |
| Equity Productions Ltd | Extraterritorial | 2015 |
| Equity School Ltd | Extraterritorial | 2011 |
| ERA Online Limited | Real estate | 2008 |
| Eran Creevy Limited | Information & communication | 2011 |
| ERB Cars Ltd | Wholesale & retail | 2025 |
| Erbs Trustee Limited | Professional & scientific | 2012 |
| Erciyes Dagi Limited | Hospitality | 2022 |
| ERD Solutions Ltd | Information & communication | 2021 |
| Eredan Limited | Wholesale & retail | 2009 |
| ERG Strategy Ltd | Professional & scientific | 2026 |
| Ergo Devices Ltd | Manufacturing | 2019 |
| Ergochair Limited | Manufacturing | 2004 |
| Ergosys Solutions Limited | Professional & scientific | 2010 |
| Erhat Limited | Hospitality | 2025 |
| Eric & Edward Properties Ltd | Real estate | 2025 |
| Eric (Education and Resources for Improving Childhood Continence) | Health & social care | 1991 |
| Eric Arthur Limited | Professional & scientific | 2020 |
| Erica Keys Limited | Hospitality | 2023 |
| Eridan 24 LP | | 2012 |
| Erika Care Ltd | Health & social care | 2015 |
| Erimos Ltd | Professional & scientific | 2023 |
| Erin Bearman Payment Consultancy Ltd | Wholesale & retail | 2024 |
| Eris Partners Limited | Professional & scientific | 2007 |
| Eriskay Parks Properties Limited | Hospitality | 2022 |
| Eriskay Properties Limited | Real estate | 2014 |
| Eritrean Habesha Community CIC | Education | 2025 |
| Erivas Limited | Administrative & support | 2025 |
| Erlic Medical Ltd | Health & social care | 2019 |
| Ermeview Environmental Solutions Ltd | Professional & scientific | 2019 |
| Ermevin Ltd | Health & social care | 2013 |
| Ernest Buck Properties Ltd | Real estate | 2026 |
| Ernest Court Management Ltd | Households | 2013 |
| Ernest Entertainment Group Ltd | Arts & recreation | 2025 |
| Ernest Gordon Recruitment Limited | Administrative & support | 2017 |
| Ernest Parks & Events Limited | Arts & recreation | 2026 |
| Ernest Promotions Ltd | Professional & scientific | 2024 |
| Ernest Sports Ltd | Arts & recreation | 2026 |
| Ernest Till & Co Ltd | Construction | 2021 |
| Ernest Till South West & Co Ltd | Construction | 2015 |
| Ernestpat Ltd | Health & social care | 2019 |
| Erock Electrical Ltd | Construction | 2017 |
| Erol GUL Ltd | Transport & logistics | 2020 |
| Eroom Limited | Administrative & support | 2001 |
| Erotic Secrets of Pompeii Ltd | Arts & recreation | 2024 |
| ERW Electrical Solutions Ltd | Construction | 2025 |
| ES Healthcare Ltd | Health & social care | 2016 |
| ES Lifts Ltd | Construction | 2024 |
| ES Property Holdings Ltd | Real estate | 2023 |
| ES Scaffolding Ltd | Construction | 2023 |
| ES Vans Ltd | Wholesale & retail | 2019 |
| ESA Foods Ltd | Hospitality | 2020 |
| ESA Lift Limited | Construction | 2013 |
| Esal Ltd | Professional & scientific | 2010 |
| Esamusa Network Ltd | Wholesale & retail | 2025 |
| ESC IT Limited | Information & communication | 2012 |
| Escalus Software Systems Ltd | Information & communication | 1999 |
| Escapade 26 Ltd | Real estate | 2021 |
| Escape and Discover Limited | Administrative & support | 2015 |
| Escape Bubble Ltd | Other services | 2020 |
| Escape Code Limited | Information & communication | 2023 |
| Escape Homes Limited | Construction | 2007 |
| Escape Rooms Bristol Ltd | Arts & recreation | 2023 |
| Escape Salons Limited | Other services | 2001 |
| Escapepads Limited | Hospitality | 2016 |
| Escargrow & Co Ltd | Real estate | 2025 |
| Escentral Limited | Education | 2020 |
| Escher Marwick Limited | Financial services | 2016 |
| Escooterparts Ltd | Wholesale & retail | 2023 |
| ESD Holdings Ltd | Professional & scientific | 2001 |
| Esea Music Ltd | Other services | 2022 |
| Eselinov Limited | Hospitality | 2025 |
| Esem Transport Ltd | Transport & logistics | 2023 |
| ESG Leisure Holdings Ltd | Financial services | 2019 |
| Esha Ehtsham Ltd | Wholesale & retail | 2026 |
| Eshalydotcom Ltd | Wholesale & retail | 2026 |
| Esher Pegrum Ltd | Professional & scientific | 2024 |
| Eshopstream Limited | Wholesale & retail | 2024 |
| Esim Global Ltd | Information & communication | 2019 |
| Eskatera Ltd | Information & communication | 2019 |
| Eskmaintanance Ltd | Manufacturing | 2023 |
| ESL Bills Limited | Administrative & support | 2017 |
| ESL Group UK Limited | Manufacturing | 2006 |
| Eslean Virtual Solutions Ltd | Administrative & support | 2024 |
| Eslee Consulting Limited | Professional & scientific | 2023 |
| ESM Partners Ltd | Information & communication | 2019 |
| Esmiley Ltd | Wholesale & retail | 2019 |
| ESO Music Group Ltd | Arts & recreation | 2019 |
| Esos Energy Ltd | Administrative & support | 2014 |
| Esotech Wearables Ltd | Professional & scientific | 2024 |
| ESP Special Batteries Limited | Manufacturing | 1988 |
| Espero Consulting Limited | Administrative & support | 2016 |
| Esplanade Management (Weymouth) Limited | Real estate | 2016 |
| Espresso Brands Ltd | Wholesale & retail | 2026 |
| Espresso Commercial Ltd | Wholesale & retail | 2023 |
| Espressobristol Limited | Hospitality | 2023 |
| Esprit Film and Television Limited | Administrative & support | 2003 |
| Esquinza Real Estate, Ltd | Real estate | 2024 |
| Esrg Developments Limited | Real estate | 2014 |