| Storm Beauty Limited | Other services | 2017 |
| Storm Building Products Limited | Extraterritorial | 2020 |
| Storm Earth Ltd | Real estate | 2021 |
| Storm GAS Ltd | Construction | 2019 |
| Storm Hair Design Limited | Other services | 2005 |
| Storm Heat Pumps Ltd | Extraterritorial | 2023 |
| Stowey Properties Ltd | Real estate | 2008 |
| STR (Bristol) Limited | Extraterritorial | 2017 |
| STR8BRANDZ Attire Ltd | Wholesale & retail | 2026 |
| Strata Planning Ltd | Professional & scientific | 2025 |
| STRATEGY121 Limited | Real estate | 2019 |
| Stratton Capital Limited | Financial services | 2024 |
| Stratton Land (Barwick) Limited | Construction | 2023 |
| Stratton Land (Crawley) Limited | Construction | 2020 |
| Stratton Land (Eastry) Limited | Construction | 2024 |
| Stratton Land (Lakeside) Limited | Construction | 2024 |
| Stratton Land (Monkton) Limited | Construction | 2024 |
| Stratton Land (Paignton) Limited | Construction | 2024 |
| Stratton Land (Rainham) Limited | Construction | 2023 |
| Stratton Land (Rochester) Limited | Construction | 2024 |
| Stratton Land (Stroud) Limited | Construction | 2024 |
| Stratton Land 3 Limited | Real estate | 2013 |
| Streamline Construction SW Limited | Construction | 2019 |
| Streamline Office Solutions Limited | Wholesale & retail | 2003 |
| Street Food Containers Ltd | Hospitality | 2022 |
| Stressline Services Limited | Health & social care | 2001 |
| Stretcholt Equestrian Centre Ltd | Arts & recreation | 2025 |
| Stringtech Ltd | Information & communication | 2023 |
| Stuart Todd Associates Limited | Administrative & support | 2012 |
| Studholme Capital Unlimited | Professional & scientific | 2026 |
| Studio Hive Limited | Administrative & support | 2014 |
| Studio Hive Properties Ltd | Real estate | 2021 |
| SUE Eve-Jones Limited | Professional & scientific | 2004 |
| Summer Land Air Conditioning Ltd | Energy | 2003 |
| Summer Land Renewables Ltd | Construction | 2010 |
| Summerzest Limited | Arts & recreation | 2016 |
| Sunbeams Nursery Limited | Health & social care | 2013 |
| Sundaes Ice Cream Parlour Limited | Hospitality | 2020 |
| Sunmosh Trading Limited | Wholesale & retail | 2026 |
| Sunnyhill 2026 Developments Limited | Construction | 2026 |
| Sunrise Child Care Ltd | Health & social care | 2023 |
| Superyacht Parts Supplier Ltd | Manufacturing | 2025 |
| Supplements by Hazel Limited | Health & social care | 2021 |
| Supplier Development Solutions Ltd | Professional & scientific | 2014 |
| Sure Insight Ltd | Information & communication | 2026 |
| Surebond Surfaces (UK) Ltd | Construction | 2011 |
| Surgihub Limited | Education | 2026 |
| Susie Cornish Translations Limited | Professional & scientific | 2002 |
| Sutherland & Brown Property Ltd | Real estate | 2024 |
| Sutton Chase Developments Limited | Real estate | 2022 |
| SW (Southwest) Joinery Ltd | Manufacturing | 2022 |
| SW Cranes Ltd | Construction | 2020 |
| SW Lettings Group Ltd | Real estate | 2026 |
| SWAG2024 Limited | Professional & scientific | 2024 |
| Swan Paul Partnership Limited | Professional & scientific | 2005 |
| Swat's Scaffolding Ltd | Construction | 2022 |
| Swatforcegroup Ltd | Administrative & support | 2025 |
| Sweatbox Boxing Academy Ltd | Arts & recreation | 2025 |
| Sweet Angels Limited | Health & social care | 2015 |
| Sweet Temptations SW Ltd | Manufacturing | 2024 |
| Sweeting and Clements Property Limited | Real estate | 2026 |
| Swift and Bold Property Management Limited | Real estate | 2022 |
| Swiftora Checkout Ltd | Wholesale & retail | 2025 |
| Swmas Group Limited | Professional & scientific | 2013 |
| Swmas Ltd | Professional & scientific | 2001 |
| Swytch Talent Ltd | Administrative & support | 2024 |
| Sydenham Community Association | Arts & recreation | 2009 |
| Sykes-Moore Estate Agents Limited | Real estate | 2021 |
| T D Bawden Agri Limited | Agriculture & fishing | 2013 |
| T D Bawden Microlights Limited | Real estate | 2012 |
| T Osborne Enterprises Ltd | Construction | 2020 |
| T&B Spedition Ltd | Transport & logistics | 2026 |
| T&I Group Ltd | Administrative & support | 2023 |
| T&T Barber Ltd | Other services | 2025 |
| T.C. Plumbing and Heating Ltd | Construction | 2017 |
| TAB Property Estate Ltd | Real estate | 2025 |
| Tables and More Limited | Arts & recreation | 2019 |
| Tactical Assault Limited | Wholesale & retail | 2021 |
| Taffy's Tree Ltd | Wholesale & retail | 2026 |
| TAJ Shop Limited | Wholesale & retail | 2025 |
| Taliesin Holdings Limited | Real estate | 2022 |
| Talisman AI Limited | Professional & scientific | 2025 |
| Talking Stick Digital Ltd | Administrative & support | 2021 |
| Talking Stick Marketing and Communications Ltd | Administrative & support | 2006 |
| Tallunt (Southwest) Ltd | Extraterritorial | 2020 |
| Tamlyn and SON Ltd | Real estate | 2006 |
| Tanasa Holdings Ltd | Construction | 2016 |
| Tapper Industrial Roofing & Maintenance Ltd | Construction | 2016 |
| Tarc Properties Ltd | Real estate | 2024 |
| Taste of Somerset Limited | Hospitality | 2002 |
| Tasty Fried Chicken (Bridgewater) Ltd | Hospitality | 2025 |
| Tastys Takeaway Ltd | Hospitality | 2025 |
| Taunton Endodontics Limited | Health & social care | 2013 |
| Taunton Property Services Limited | Construction | 2014 |
| Taunton RD Service Station Limited | Wholesale & retail | 2005 |
| Taunton Road Car Centre Limited | Wholesale & retail | 2005 |
| Taunton Studio Limited | Arts & recreation | 2026 |
| Taunton Training Limited | Other services | 2012 |
| Taylor West | Wholesale & retail | 1935 |
| Taylor's Fencing Ltd | Administrative & support | 2025 |