| Dumale Limited | Professional & scientific | 2020 |
| Dutt Medical Limited | Health & social care | 2017 |
| Duxtus Ltd | Financial services | 2022 |
| Dynamic Rentals Europe Limited | Administrative & support | 2019 |
| DZD Cars Limited | Wholesale & retail | 2024 |
| Délice Boutique Ltd | Wholesale & retail | 2025 |
| E&M Operations Ltd | Wholesale & retail | 2022 |
| E- Cube Resources Limited | Information & communication | 2007 |
| E-Shopme Ltd | Wholesale & retail | 2024 |
| E. K. Technologies Ltd. | Information & communication | 2012 |
| E1 UK Consulting Limited | Information & communication | 2020 |
| E1 UK Holdings Limited | Information & communication | 2020 |
| E2S Capital Ltd | Real estate | 2026 |
| EA Initiative Ltd | Financial services | 2023 |
| Eagle Nest Homes Ltd | Real estate | 2026 |
| Eagle Realty Ltd | Real estate | 2024 |
| Ealing Food Hall Ltd | Real estate | 2025 |
| Ealing Windows Ltd | Construction | 2023 |
| Eappsys Limited | Information & communication | 2007 |
| Earth Green Pack Ltd | Manufacturing | 2022 |
| Ease Care Ltd | Health & social care | 2019 |
| East Africa Buy & Sale Ltd | Wholesale & retail | 2026 |
| East END Musics Limited | Information & communication | 2020 |
| Eaststandard Ltd | Construction | 2022 |
| EAT Your Cake Ltd | Information & communication | 2016 |
| Eateam Solutions Limited | Information & communication | 2024 |
| Eateroo Limited | Hospitality | 2025 |
| EBM Professional Care Services Limited | Health & social care | 2013 |
| Ebridcom Limited | Households | 2019 |
| Echo Street Productions Ltd | Information & communication | 2025 |
| Eclat London Executive Training Limited | Education | 2017 |
| Eco Bliss BE+ Limited | Wholesale & retail | 2023 |
| Eco Pro Cleaning Ltd | Administrative & support | 2021 |
| Eco-Ked Limited | Transport & logistics | 2021 |
| ECS Techologies Limited | Information & communication | 2023 |
| Ecumenical Synod of Bishops, Archbishops, Apostles and Senior Clergy Ltd | Other services | 2023 |
| ED Engineering Design Group - Tasameem Limited | Construction | 2017 |
| EDC Facilities Ltd | Professional & scientific | 2024 |
| Eden Massage Ltd | Other services | 2026 |
| Eder Limited | Transport & logistics | 2017 |
| Ediface Ltd | Information & communication | 2014 |
| Ediluma Ltd | Wholesale & retail | 2022 |
| Editing Education Ltd | Professional & scientific | 2025 |
| Education Enterprise Ltd | Education | 2026 |
| Education Guidance Limited | Administrative & support | 2026 |
| EG VIP Chauffeurs London Ltd | Transport & logistics | 2019 |
| Egham Fresh Limited | Hospitality | 2021 |
| Egyptian Youth Union Abroad CIC | Administrative & support | 2025 |
| Eicr and Property Uplift Ltd | Manufacturing | 2020 |
| Eighty Seven Visuals Limited | Professional & scientific | 2017 |
| Ekerin Consulting Ltd | Information & communication | 2019 |
| EL Educational Psychology Ltd | Education | 2022 |
| El-Install Limited | Construction | 2020 |
| ELA Tatiana Photography Limited | Information & communication | 2013 |
| Eldridge Strategy Partners Ltd | Information & communication | 2025 |
| Electra Film and Television Limited | Other services | 1987 |
| Elegant Excellence Ltd | Professional & scientific | 2025 |
| Elevare Atlas Ltd | Professional & scientific | 2025 |
| Eleven Maintenance Limited | Administrative & support | 1999 |
| Eleven Staffing Services Limited | Administrative & support | 2020 |
| Elicit Training Ltd | Administrative & support | 2017 |
| Elite Apartments London Ltd | Hospitality | 2018 |
| Elite Body Repair Ltd | Wholesale & retail | 2019 |
| Elite Construction Building Services Limited | Construction | 2018 |
| Elite Construction London Limited | Construction | 2015 |
| Elite Constructions (UK) Limited | Construction | 2012 |
| Elite Dynamics London Limited | Information & communication | 2023 |
| Elite Meddent Limited | Education | 2025 |
| Elite Paws Limited | Agriculture & fishing | 2025 |
| Elite Pro Services Limited | Professional & scientific | 2024 |
| Elite Property West Ltd | Real estate | 2026 |
| Elite Roofing Industries Limited | Construction | 2019 |
| Elite Travel Destinations Limited | Other services | 2017 |
| Elitech Consulting Ltd | Information & communication | 2025 |
| Elithien Ltd | Wholesale & retail | 2020 |
| Elliott Power Ltd | Information & communication | 2021 |
| Elsa Kewbridge Ltd | Other services | 2017 |
| Elsie Domiciliary Care Limited | Health & social care | 2024 |
| Elviora Ltd | Wholesale & retail | 2026 |
| EME Digital Limited | Information & communication | 2002 |
| Emerald Hill Capital Limited | Financial services | 2019 |
| Emguidance International Limited | Information & communication | 2023 |
| Emguidance Limited | Information & communication | 2021 |
| Emplaw Services Limited | Professional & scientific | 2021 |
| Enerise UK Limited | Wholesale & retail | 2024 |
| Enibas Holding Ltd | Financial services | 2022 |
| Enji Technologies Ltd | Professional & scientific | 2023 |
| Enoch Square Accounting Limited | Financial services | 2019 |
| Entire Automotive Ltd | Wholesale & retail | 2012 |
| Epaper Designs Limited | Information & communication | 2021 |
| Epics Services Limited | Information & communication | 2020 |
| EPS Global EPC LLP | | 2023 |
| ER Taxi Ltd | Wholesale & retail | 2022 |
| Erbil Autoworks Ltd | Wholesale & retail | 2025 |
| Erpbiz Solutions PVT. Ltd. | Information & communication | 2026 |
| Errebi Consulting Ltd | Professional & scientific | 2023 |
| ERS Holders Ltd | Wholesale & retail | 2026 |
| Es-Doble London Ltd | Wholesale & retail | 2026 |
| Escape London Ltd | Arts & recreation | 2016 |
| Esmeralda's of Brentford Limited | Wholesale & retail | 2019 |