| DDS Logistics 95 Ltd | Wholesale & retail | 2021 |
| DE Gustibus Limited | Manufacturing | 2009 |
| Decillion Digital Limited | Wholesale & retail | 2020 |
| Decisys Ltd | Information & communication | 2016 |
| Decochic Property Limited | Households | 2024 |
| Decorcolour Limited | Construction | 2014 |
| Deep AI Diagnostics Limited | Health & social care | 2022 |
| Deep Marine Ltd | Professional & scientific | 2025 |
| Delicday Ltd | Manufacturing | 2025 |
| Deljio Ltd | Wholesale & retail | 2025 |
| Delocort Property Ltd | Real estate | 2024 |
| Derman Safety & Hygiene Limited | Health & social care | 2008 |
| Dermot Crowley Limited | Arts & recreation | 2013 |
| Dermz Laboratories Ltd | Wholesale & retail | 2015 |
| Desert Engineering Ltd | Professional & scientific | 2012 |
| Desert Rose Tourism Limited | Administrative & support | 2023 |
| Design Manufacturing Group Limited | Wholesale & retail | 2012 |
| Desire Aesthetics and Academy Limited | Other services | 2024 |
| Desire Facial Aesthetics Ltd | Other services | 2023 |
| Destiny Helpers Nursery Limited | Education | 2017 |
| Devstack Ltd | Information & communication | 2024 |
| DEX Refurbishments Ltd | Construction | 2018 |
| Dextra Solutions Limited | Professional & scientific | 2018 |
| Dfhg Feltham Ltd | Hospitality | 2026 |
| DG Chehlarski Ltd | Other services | 2006 |
| DGL Media Solutions Ltd | Professional & scientific | 2025 |
| Dhatt Construction London Limited | Construction | 2025 |
| Dhrush Tech Limited | Financial services | 2024 |
| Di-Nt Limited | Information & communication | 2020 |
| Diamond and Dice Limited | Real estate | 2026 |
| Diamond London Ltd | Real estate | 2021 |
| Diamond Move Limited | Real estate | 2005 |
| Diba Beauty Ltd | Other services | 2022 |
| Digant Ltd | Professional & scientific | 2026 |
| Digilectronix Group Ltd | Information & communication | 2016 |
| Digital Accelerator Ltd | Wholesale & retail | 2022 |
| Digital Bwave Limited | Information & communication | 2026 |
| Digital Development Solutions Ltd | Information & communication | 2026 |
| Digital Dust Ltd | Professional & scientific | 2015 |
| Digital Marketing Revolution Ltd | Wholesale & retail | 2019 |
| Digital Visionary Services Limited | Information & communication | 2025 |
| Digitalo Limited | Financial services | 2018 |
| Digitaz Homes Limited | Real estate | 2021 |
| Digithrive Consulting Limited | Information & communication | 2023 |
| Diligent Medics Ltd | Health & social care | 2023 |
| Dinedash Ltd | Hospitality | 2024 |
| Dines Worldwide Ltd | Arts & recreation | 2023 |
| Dipix Europe Limited | Manufacturing | 2005 |
| Direct Cargo Express Ltd | Transport & logistics | 2024 |
| Disaster Care Capital Ltd | Administrative & support | 2017 |
| Dispatchlayer Limited | Information & communication | 2026 |
| Diversity Media Limited | Professional & scientific | 2025 |
| Divine and Ridiculous Limited | Arts & recreation | 2025 |
| Diztortion Productions Limited | Arts & recreation | 2014 |
| DK Maintenance and Supplies Ltd | Construction | 2024 |
| DLA Logistics UK Ltd | Transport & logistics | 2020 |
| DM Build Group Ltd | Manufacturing | 2025 |
| DM Plumbing Engineers Limited | Construction | 2015 |
| DM TEQ Ltd | Professional & scientific | 2026 |
| Dmnd Investment Consultants Ltd | Professional & scientific | 2007 |
| DN Holding Group Ltd | Professional & scientific | 2026 |
| DN Search Ltd | Administrative & support | 2020 |
| DNO Estates LLP | | 2020 |
| Dock House Ltd | Real estate | 2019 |
| Docutech Limited | Information & communication | 2018 |
| Doggies Furever Hydrohub Group Ltd | Financial services | 2026 |
| Dogovor Consulting Ltd | Professional & scientific | 2022 |
| Doing Diversity Differently Ltd | Professional & scientific | 2022 |
| Domain Earth Limited | Real estate | 2021 |
| Domainiq Consulting Limited | Information & communication | 2018 |
| Domps Ltd | Other services | 2009 |
| Dona Cleaning Services Ltd | Administrative & support | 2024 |
| Donava Limited | Information & communication | 2018 |
| Doodle Collection Ltd | Other services | 2020 |
| Doorstep Transport Limited | Transport & logistics | 2021 |
| Dore’S Development Industry Ltd | Real estate | 2025 |
| Dormant Company UK Limited | Professional & scientific | 2006 |
| Dorothysremovals Ltd | Transport & logistics | 2018 |
| DOUBLE-02 Limited | Information & communication | 2003 |
| Dowellus Ltd | Construction | 2024 |
| Doxabeta Cloud Academy CIC | Information & communication | 2023 |
| Doxabeta Limited | Information & communication | 2021 |
| Doylesmith Ltd | Construction | 2022 |
| Dozo Tea Ltd | Hospitality | 2023 |
| DPA Construction London Limited | Construction | 2021 |
| DQ Security Limited | Administrative & support | 2018 |
| DR Thomy Kouremada-Zioga Limited | Health & social care | 2020 |
| DR. Smith Medical Ltd. | Health & social care | 2014 |
| Dragon Emeraude Ltd | Information & communication | 2021 |
| Dramura Ltd | Information & communication | 2025 |
| Drew Print Ltd | Professional & scientific | 2026 |
| Drew's GIN Ltd | Manufacturing | 2022 |
| Drivato Services Group Ltd | Wholesale & retail | 2026 |
| Driveepic Ltd | Education | 2010 |
| Driver Force Management Ltd | Administrative & support | 2025 |
| Drivex Engineering Ltd | Professional & scientific | 2024 |
| Drop of Sunnah Ltd | Professional & scientific | 2025 |
| DTS Consultancy Ltd | Information & communication | 2026 |
| Duda Masters Ltd | Construction | 2025 |
| DUM Electrical Services Ltd | Manufacturing | 2026 |