| Elephant Designer Childrenswear Ltd | Wholesale & retail | 2019 |
| Elevate EBP Limited | Education | 1998 |
| Elevate Golf Academy Ltd | Education | 2025 |
| Elhir Ltd | Health & social care | 2023 |
| Elite Events Group Ltd | Administrative & support | 2026 |
| Elite Focus Recruitment Limited | Administrative & support | 2026 |
| Elite Motorcycles Garage Ltd | Wholesale & retail | 2026 |
| Elite Motorcycles Ltd | Wholesale & retail | 2024 |
| Elite Safety Systems Limited | Construction | 2011 |
| Elite UK Homes Ltd | Construction | 2015 |
| Eliteinviteliverpool Ltd | Manufacturing | 2016 |
| ELM Access Solutions Ltd | Manufacturing | 2026 |
| ELM Residential Limited | Real estate | 2020 |
| Emisworld Services Ltd | Hospitality | 2025 |
| Emlana Limited | Other services | 2025 |
| Empower Path Assessment Ltd | Health & social care | 2026 |
| Emtb Investments Limited | Real estate | 2025 |
| Enclad Limited | Construction | 2010 |
| Encycam UK Limited | Information & communication | 2024 |
| Endale Consulting Limited | Health & social care | 2012 |
| Endrive Commercial Limited | Wholesale & retail | 2025 |
| Endrive Limited | Administrative & support | 2024 |
| Engage & Change CIC | Education | 2015 |
| Engage UX Consultancy Ltd | Professional & scientific | 2026 |
| Enhance X Works Ltd | Construction | 2025 |
| Ennerdale Builders Ltd | Construction | 2026 |
| Entreprenreducation Ltd | Education | 2025 |
| Envases Hull Ltd | Manufacturing | 2014 |
| Envases Liverpool Ltd | Manufacturing | 2014 |
| ENY ADS Ltd | Wholesale & retail | 2025 |
| Epoch Training and Research (Europe) Ltd | Professional & scientific | 2010 |
| ER Bellavita Group UK Ltd | Wholesale & retail | 2025 |
| ESC Estates Limited | Real estate | 2025 |
| Esra KAI Limited | Hospitality | 2018 |
| Ethnos Media Limited | Professional & scientific | 2018 |
| ETZ Financial Solutions Limited | Financial services | 2019 |
| European Welding Supplies Ltd | Wholesale & retail | 2014 |
| Everbook Photobooks Ltd | Manufacturing | 2025 |
| Evergreen Integrated Services Limited | Construction | 2026 |
| Everyone Move C.I.C. | Arts & recreation | 2022 |
| Evolution Fitness Professionals Ltd | Other services | 2010 |
| Evolution Parade Limited | Wholesale & retail | 2025 |
| Excel Housing Solutions | Hospitality | 2013 |
| Excel Travel Express (UK) Limited | Administrative & support | 2008 |
| Excursion.Studio Ltd | Professional & scientific | 2021 |
| Exel Ceilings & Partitions Ltd | Construction | 2025 |
| Exel Drylining & Plastering Limited | Construction | 2016 |
| Expect Ltd. | Health & social care | 1989 |
| Expert Construction Services Ltd | Construction | 2024 |
| Expertx Cleaning Ltd | Professional & scientific | 2025 |
| Express Car Clinic Ltd | Wholesale & retail | 2026 |
| Eyecandy Delivery 2 Limited | Hospitality | 2019 |
| Fables & Fire Ltd | Other services | 2024 |
| Facevisual Limited | Real estate | 1987 |
| Falafel Chef Ltd | Hospitality | 2022 |
| Farrell Welding Fabrication Limited | Manufacturing | 2014 |
| Fast Fit L20 Ltd | Wholesale & retail | 2026 |
| Fazakerley Rewinds Limited | Manufacturing | 2008 |
| Fenwell Commercial Limited | Real estate | 2019 |
| Fenwell Estates Ltd | Construction | 2003 |
| Fenwell Residential Ltd | Real estate | 2017 |
| Fernhill Commercial Property Ltd | Real estate | 2012 |
| Fighting Together Limited | Education | 2025 |
| Find Your Backbone Limited | Health & social care | 2024 |
| Finished Edges Limited | Manufacturing | 2025 |
| Finite Research Ltd | Professional & scientific | 2021 |
| Finnigans Chippy Ltd | Hospitality | 2026 |
| Finnigans Tasty Pizza Ltd | Hospitality | 2024 |
| Fiorucci Ltd | Other services | 2019 |
| Firework Shop L20 Ltd | Wholesale & retail | 2025 |
| First Call Business Solutions Limited | Extraterritorial | 2019 |
| Fisher OPS Ltd | Water & waste | 2026 |
| Five Star Steel Products Manufacturing Ltd | Construction | 2022 |
| FJC Excavation Limited | Water & waste | 2014 |
| Fjsdesignandbuild Limited | Construction | 2017 |
| Flagpole Trading Limited | Wholesale & retail | 2024 |
| Flanagan Electrical Ltd | Construction | 2014 |
| Fleetaxis Limited | Transport & logistics | 2026 |
| Fleetwood's Minimart Ltd | Wholesale & retail | 2019 |
| Flexiwall Company Limited | Construction | 1974 |
| Flippin Good Markets Ltd | Hospitality | 2024 |
| Flocon Holdings Limited | Financial services | 2025 |
| Floor 18 Ltd | Construction | 2026 |
| Floor Trims Direct Ltd | Construction | 2024 |
| Flooring Excellence Ltd | Wholesale & retail | 2022 |
| Floorless Cleaning Specialists Limited | Administrative & support | 2023 |
| Flora Care Group Limited | Administrative & support | 2023 |
| Flora Care Solutions (1) Ltd | Administrative & support | 2023 |
| Floria Cakehouse Ltd | Manufacturing | 2025 |
| Flourish Hub Group Ltd | Financial services | 2023 |
| Flourish Learning Ltd | Information & communication | 2007 |
| Flourish Works Ltd | Administrative & support | 2021 |
| Flow Transport Limited | Wholesale & retail | 2024 |
| Flower GUY Florist Liverpool Ltd | Wholesale & retail | 2024 |
| FMF Events Ltd | Arts & recreation | 2024 |
| Fonotech Limited | Administrative & support | 2017 |
| Food Store (Aughton) Limited | Wholesale & retail | 2017 |
| Food Supper Bar Ltd | Hospitality | 2024 |
| Foodaholic 666 Ltd | Hospitality | 2025 |
| Forageplus Limited | Wholesale & retail | 2005 |