| D C Tile Masters Ltd | Construction | 2022 |
| D E Mccluskey Ltd | Information & communication | 2018 |
| D&G Flooring Services Limited | Construction | 2019 |
| D-8 Development & Lettings Limited | Real estate | 2025 |
| D.G.L.O. Holdings Limited | Financial services | 2021 |
| D.L. Skerrett Engineering Limited | Wholesale & retail | 2014 |
| D.S Trading Ltd | Wholesale & retail | 2020 |
| Daniel Kenny Limited | Other services | 2019 |
| Darian Hotels Limited | Hospitality | 2024 |
| Darinip Winz Ltd | Wholesale & retail | 2024 |
| Darras CUT Ltd | Other services | 2021 |
| Das&Constructions Solutions Ltd | Construction | 2022 |
| Davies Products (Liverpool) Limited | Wholesale & retail | 1947 |
| Davies Products Ltd | Professional & scientific | 2002 |
| Davies Storage & Distribution Ltd | Transport & logistics | 2026 |
| Davis Kavanagh Limited | Real estate | 1993 |
| Dazzle Dash Ltd | Administrative & support | 2025 |
| DBF Klothing Limited | Wholesale & retail | 2025 |
| Dbpm Ltd | Professional & scientific | 2021 |
| DBW Partners Ltd. | Wholesale & retail | 2024 |
| DDD Property One Ltd | Real estate | 2025 |
| Ddsf Property Investment Ltd | Real estate | 2024 |
| DDT Propertees Ltd | Construction | 2025 |
| DEA Group Holdings Ltd | Financial services | 2024 |
| Delightshopper Ltd | Wholesale & retail | 2026 |
| Delux Group Ltd | Construction | 2025 |
| Demax Trading Limited | Information & communication | 2022 |
| Denis Moft Avram Limited | Administrative & support | 2022 |
| Dfonte Global Services Ltd | Wholesale & retail | 2026 |
| DG Posty Ltd | Transport & logistics | 2025 |
| Diamine International Limited | Manufacturing | 2017 |
| Digital Arts Box CIC | Education | 2016 |
| Digital Spot Ltd | Wholesale & retail | 2015 |
| Dirty Unicorn Ltd | Wholesale & retail | 2019 |
| Discount Store L20 Ltd | Wholesale & retail | 2026 |
| Distro Flow Ltd | Wholesale & retail | 2023 |
| Ditto Construction Ltd | Construction | 2020 |
| Divergent Active Ltd | Hospitality | 2020 |
| Diverse Sports C.I.C. | Education | 2020 |
| Divine Desserts UK Ltd | Manufacturing | 2010 |
| Divine Grace Africa Foods Store Limited | Hospitality | 2021 |
| Dj's Party Shop Ltd | Other services | 2019 |
| DJW Process Engineering Ltd | Professional & scientific | 2024 |
| DLD Construction Consultancy Limited | Construction | 2019 |
| DM Couriers Ltd | Transport & logistics | 2025 |
| DM Electrical Services NW Limited | Construction | 2024 |
| Dmac Marine Limited | Manufacturing | 2022 |
| DMH (NW) Ltd | Real estate | 2020 |
| DND Travel Ltd | Transport & logistics | 2023 |
| DOC Civils Ltd | Construction | 2024 |
| Dockside Electrical Limited | Construction | 2025 |
| Done Mate Ltd | Wholesale & retail | 2026 |
| Donnelly’S Adventure Travel Ltd | Administrative & support | 2025 |
| Door Factory NW Limited | Manufacturing | 2025 |
| Doors(Liverpool) Limited | Wholesale & retail | 2025 |
| Dorexon.Co Ltd | Construction | 2025 |
| Dorin Both Ltd | Transport & logistics | 2024 |
| DPP Law Solicitors LLP | | 2024 |
| DR Emmanuel George Limited | Health & social care | 2017 |
| DR Maassarani & Partners Ltd | Health & social care | 2011 |
| DR. F Maassarani Ltd | Financial services | 2009 |
| Dragons Breath Forge Ltd | Manufacturing | 2008 |
| Drshrooms Ltd | Hospitality | 2024 |
| DSW Development & Build Ltd | Construction | 2024 |
| Dudley Suresh Ltd | Wholesale & retail | 2026 |
| Dunham Dean Advisory Limited | Professional & scientific | 2017 |
| Dunne Construction Ltd | Construction | 2020 |
| Dures Building & Groundworks Limited | Construction | 2017 |
| Duvet Day Ltd | Wholesale & retail | 2020 |
| DVM Roofing Ltd | Construction | 2025 |
| DW Facades Ltd | Construction | 2019 |
| DW Wind Ltd | Manufacturing | 2023 |
| DZ Builders Ltd | Construction | 2025 |
| D’Urso Medical Ltd | Health & social care | 2023 |
| E Systems Engineering Society Limited | Professional & scientific | 2019 |
| E&L Scaffolding Ltd | Construction | 2020 |
| EAD Development Services Limited | Construction | 2023 |
| Eagle Nursing Services Ltd | Health & social care | 2013 |
| Earlcore Ltd | Wholesale & retail | 2025 |
| Easi-Way Mobility Limited | Manufacturing | 2003 |
| Easy Drive Motors Ltd | Wholesale & retail | 2026 |
| Eavy Apparel Ltd | Wholesale & retail | 2025 |
| Eclipse Flooring North West Ltd | Construction | 2021 |
| Ecomix Limited | Manufacturing | 2011 |
| Ecomix North West Limited | Manufacturing | 2013 |
| Eddarbridge (North West) Limited | Construction | 2011 |
| Edge Autos Liverpool Ltd | Wholesale & retail | 2022 |
| Edsi Limited | Manufacturing | 2017 |
| Edtechlkuk Limited | Information & communication | 2026 |
| EGC Construction Ltd | Construction | 2016 |
| EGO Transport Services Limited | Transport & logistics | 2017 |
| EI Realty Ltd | Real estate | 2025 |
| Eidas Investments Ltd | Real estate | 2023 |
| Eimear Mcaleenan Ltd | Wholesale & retail | 2025 |
| EIO Joinery Ltd | Construction | 2020 |
| Eiwa Trading Limited | Wholesale & retail | 2025 |
| EJB Projects Liverpool Ltd | Construction | 2026 |
| EKO Taste Limited | Hospitality | 2025 |
| EL Puerto Ltd | Hospitality | 2026 |
| ELA Media Limited | Wholesale & retail | 2022 |