| Strive Courier Ltd | Transport & logistics | 2022 |
| Strix Insights Limited | Professional & scientific | 2024 |
| Strobe Management Group Ltd | Administrative & support | 2025 |
| Strong Edges Ltd | Wholesale & retail | 2021 |
| Stroodpeak Paper Services Limited | Professional & scientific | 1994 |
| Structco Ltd | Professional & scientific | 2024 |
| Structeneo Limited | Administrative & support | 2022 |
| Structura Engineering Limited | Wholesale & retail | 2001 |
| Structured Outlook Property Management Limited | Real estate | 2019 |
| Structured Outlooks Ltd | Hospitality | 2000 |
| Stsherazi Ltd | Wholesale & retail | 2024 |
| Stuchall Care Limited | Professional & scientific | 2020 |
| Student HMO Group UK Limited | Extraterritorial | 2007 |
| Student Hub Ltd | Wholesale & retail | 2026 |
| Student Paradise Ltd | Education | 2025 |
| Student Scrans Ltd | Hospitality | 2026 |
| Studio Black Limited | Wholesale & retail | 2024 |
| Studio Calvagno Ltd | Professional & scientific | 2021 |
| Studio DBD Limited | Professional & scientific | 2014 |
| Studio Enar Ltd | Professional & scientific | 2012 |
| Studio Hetain Patel Limited | Arts & recreation | 2020 |
| Studio Hoodless Ltd | Professional & scientific | 2022 |
| Studio Melo Ltd | Professional & scientific | 2025 |
| Studio Nick Ltd | Professional & scientific | 2018 |
| Studio of Cosmetics Ltd | Other services | 2018 |
| Studio Saoirse Limited | Arts & recreation | 2026 |
| Studio Taitt Ltd | Professional & scientific | 2021 |
| Studio Temp Ltd | Professional & scientific | 2020 |
| Studiojom Architects Limited | Construction | 2025 |
| STUDIOZ3 Ltd | Arts & recreation | 2025 |
| Stuff and Bucks Ltd | Wholesale & retail | 2019 |
| Stumble Inn Rental Limited | Real estate | 2018 |
| Style Blinds Limited | Wholesale & retail | 2024 |
| Style Bridge Ltd Ltd | Wholesale & retail | 2025 |
| Style Spot Limited | Administrative & support | 2015 |
| Style Stick Limited | Manufacturing | 2015 |
| Styled by Celeste Ltd | Wholesale & retail | 2022 |
| Styledbyk Limited | Other services | 2025 |
| Stylesync Ltd | Wholesale & retail | 2025 |
| Stylo Online Ltd | Wholesale & retail | 2015 |
| Stylonic Ltd | Wholesale & retail | 2020 |
| SU Foods Ltd | Manufacturing | 2019 |
| Suaim Limited | Real estate | 2026 |
| Suave Direct Limited | Wholesale & retail | 2021 |
| SUB for YOU Ltd | Hospitality | 2020 |
| Subhani Products Limited | Wholesale & retail | 2023 |
| Sublyme Cosmetics Limited | Wholesale & retail | 2013 |
| Succeed Recruitment Solutions Limited | Administrative & support | 2012 |
| Success Auto Trade Ltd | Wholesale & retail | 2025 |
| Success Team UK Ltd | Wholesale & retail | 2024 |
| SUE Goggins Limited | Health & social care | 2018 |
| Suffy's Barber Limited | Other services | 2025 |
| Sufi 9266 Consultants Ltd | Professional & scientific | 2015 |
| Sufi Holdings Ltd | Households | 2024 |
| Sugar Daddies Ltd | Wholesale & retail | 2022 |
| Sugar Safari Ltd | Wholesale & retail | 2025 |
| Suhail Mahmood Ltd | Professional & scientific | 2024 |
| Suhana Khan Ltd | Wholesale & retail | 2025 |
| Suite 4:06 Ltd | Wholesale & retail | 2023 |
| Sukran & Surya Ltd | Wholesale & retail | 2021 |
| Sukula Group Ltd | Hospitality | 2023 |
| Sulaimanibreakfast Ltd | Hospitality | 2026 |
| Sulerico Ltd | Wholesale & retail | 2020 |
| Sull Systems Ltd | Professional & scientific | 2013 |
| Sullys Haulage Services Ltd | Transport & logistics | 2016 |
| Sultan Building Ltd | Construction | 2025 |
| Sultan Meat Products Limited | Wholesale & retail | 1997 |
| Sultan Quality Meats Ltd | Manufacturing | 2014 |
| Sultan Sale Limited | Hospitality | 2024 |
| Sultan Sofas and Carpentry Ltd | Manufacturing | 2025 |
| Sultan Ventures Ltd | Wholesale & retail | 2025 |
| SUMA888 Ltd | Real estate | 2024 |
| Sumit Panda Cricket Academy Limited | Education | 2023 |
| Summ AI Agency Ltd | Information & communication | 2025 |
| Summacare Limited | Extraterritorial | 2000 |
| Summaya ALI Ltd | Health & social care | 2022 |
| Summerfields Court Ltd | Real estate | 2019 |
| Summerhayes Radiological Protection Services Limited | Professional & scientific | 2011 |
| Summerseat Properties Ltd | Real estate | 2022 |
| Summertown Roofers Limited | Construction | 2025 |
| Summit Advisors Limited | Professional & scientific | 2025 |
| Summit Construction NW Limited | Construction | 2025 |
| Summit Consultancy UK Ltd | Information & communication | 2005 |
| Summit Design Services Limited | Professional & scientific | 2025 |
| Summit Holdings NW Limited | Real estate | 2025 |
| Summit Leisure (KC) Limited | Arts & recreation | 2016 |
| Summoners Vault Ltd | Wholesale & retail | 2025 |
| Sun Osteo Ltd | Health & social care | 2018 |
| Sun Road Corporate Trustee Limited | Other services | 2026 |
| Sun Road Holdco Ltd | Financial services | 2026 |
| Sun Road Limited | Financial services | 2023 |
| Sunglen Properties Ltd | Construction | 2004 |
| Sunhq Ltd | Other services | 2023 |
| Sunkoon Ltd | Real estate | 2022 |
| Sunmelt Ltd | Information & communication | 2016 |
| Sunnah Currency Ltd | Manufacturing | 2021 |
| Sunny Airways Ltd | Administrative & support | 2023 |
| Sunny Skies Care Ltd | Health & social care | 2023 |
| Sunny View Landscaping Ltd | Administrative & support | 2025 |
| Sunraysuk Ltd | Wholesale & retail | 2023 |