| Suba Shini Ltd | Wholesale & retail | 2026 |
| Submarine Manufacturing and Products Limited | Wholesale & retail | 1991 |
| Subsea & Pipeline Engineering Limited | Professional & scientific | 2017 |
| Subsea Consulting Ltd | Information & communication | 2020 |
| Success Suits ALL CIC | Other services | 2023 |
| Sudi Abbey Ltd | Wholesale & retail | 2024 |
| Sudi Cromwell Ltd | Wholesale & retail | 2022 |
| Sudi Foxhall Ltd | Wholesale & retail | 2019 |
| Sudi Layton Ltd | Wholesale & retail | 2019 |
| Sudi Management Retail Limited | Wholesale & retail | 2012 |
| Sudi Retail Ltd | Wholesale & retail | 2024 |
| Sudi Waterloo Ltd | Wholesale & retail | 2025 |
| Sudi Wholesale Ltd | Wholesale & retail | 2024 |
| Sufi Coffee Ltd | Hospitality | 2025 |
| Suitbae Ltd | Wholesale & retail | 2022 |
| Suites by the Sea Ltd | Hospitality | 2025 |
| Suli House Limited | Hospitality | 2024 |
| Sulis Kitchen 110 Limited | Hospitality | 2026 |
| Sullivan's Bar Limited | Hospitality | 2020 |
| Sultan Empire Limited | Hospitality | 2025 |
| Sultans VEG and Fruit Limited | Wholesale & retail | 2025 |
| Suman Bhattarai Ltd | Wholesale & retail | 2026 |
| Sun Kebab Ltd | Hospitality | 2025 |
| Sunbeam Quilting Company Limited | Manufacturing | 2016 |
| Sunber Trade Ltd | Wholesale & retail | 2024 |
| Suncrest Hospitality Limited | Hospitality | 2025 |
| Sundaram Capital Limited | Financial services | 2021 |
| Sunny Deol Limited | Wholesale & retail | 2008 |
| Sunrise Care Support Ltd. | Health & social care | 2022 |
| Sunrise Hotel Blackpool Ltd | Financial services | 2024 |
| Sunset Palatine Ltd | Hospitality | 2022 |
| Sunshine Splash Limited | Wholesale & retail | 2025 |
| Super APE Limited | Wholesale & retail | 2019 |
| Super Music Studio Limited | Information & communication | 2009 |
| Super Silverback Ltd | Arts & recreation | 2024 |
| Super Wans Limited | Hospitality | 2021 |
| Supernova Living Limited | Wholesale & retail | 2017 |
| Support Products & Services Ltd | Administrative & support | 2018 |
| Sure Media Ltd | Information & communication | 2019 |
| Sure Seal Silicon Services Limited | Construction | 2024 |
| Sureness Limited | Manufacturing | 2017 |
| Suresign (Fylde) Limited | Administrative & support | 2015 |
| Surety Fire Solutions Limited | Professional & scientific | 2014 |
| Surety Health and Safety Solutions Limited | Extraterritorial | 2016 |
| Surety Safety Limited | Extraterritorial | 2016 |
| Surety Solutions Limited | Professional & scientific | 2016 |
| Surgical Insight Ltd | Information & communication | 2025 |
| Sussex Trichology Ltd | Health & social care | 2015 |
| Sutcliffes Private Hotel Limited | Hospitality | 1963 |
| Sutechdz Ltd | Wholesale & retail | 2021 |
| Suttonbeck Finance Ltd. | Financial services | 2023 |
| SW Data Consulting Ltd | Information & communication | 2018 |
| SW Offshore Electrical Limited | Mining & quarrying | 2014 |
| SW Properties & Investments Ltd | Real estate | 2025 |
| SW Vape Limited | Wholesale & retail | 2025 |
| Swakeleys PUB Ltd | Hospitality | 2026 |
| Swallow Court RTM Company Ltd | Households | 2014 |
| Swan House Management Limited | Households | 2009 |
| Swan in Ltd | Hospitality | 2023 |
| Sway Marketing Ltd | Professional & scientific | 2018 |
| Sweatherell Limited | Transport & logistics | 2025 |
| Sweet N Sour Limited | Hospitality | 2012 |
| Sweet Peas Nursery & PRE School Ltd | Health & social care | 2018 |
| Swift Asset Holdings Limited | Real estate | 2026 |
| Swift Car Deliveries Ltd | Transport & logistics | 2013 |
| Swift Hospitality Consultants Ltd | Professional & scientific | 2021 |
| Swift Refurbs Ltd | Construction | 2022 |
| Swift Stock Ltd | Other services | 2015 |
| Swimming Masters Limited | Education | 2019 |
| Switch 365 Ltd | Professional & scientific | 2012 |
| Switch 365 Technologies Limited | Information & communication | 2024 |
| Switch and Save Limited | Other services | 2021 |
| Switched on Electrical Contractors (NW) Ltd | Other services | 2018 |
| Switchpay Ltd | Financial services | 2024 |
| SWL Contractors Ltd | Other services | 2025 |
| SWM Contracting Ltd | Energy | 2017 |
| Sword Yachting UK Ltd. | Extraterritorial | 2024 |
| SYA Yachting Limited | Extraterritorial | 2023 |
| Syamk Ltd | Wholesale & retail | 2025 |
| Sylver Limited | Administrative & support | 2006 |
| Synchrony Solutions Limited | Information & communication | 2009 |
| Synec Ltd | Professional & scientific | 2022 |
| Synergy Education Trust Limited | Education | 2022 |
| Syniol Limited | Information & communication | 2020 |
| Synova Biosciences Ltd | Manufacturing | 2025 |
| Syon Gate Associates Ltd | Professional & scientific | 2014 |
| Sysmobic Limited | Information & communication | 2005 |
| SYSTEM2SYSTEM Limited | Manufacturing | 2011 |
| T & a Contracting Limited | Agriculture & fishing | 2007 |
| T & G Spraybooths & Pipework Services Ltd | Wholesale & retail | 2014 |
| T & J O'Kane Ltd | Wholesale & retail | 2025 |
| T & S Cable Jointing Limited | Administrative & support | 2011 |
| T & S Joinery (UK) Limited | Construction | 2012 |
| T and S Vehicle Solutions Limited | Wholesale & retail | 2013 |
| T C Travel (Blackpool) Ltd | Transport & logistics | 2025 |
| T Heatley's Paint & Bodywork Limited | Wholesale & retail | 2007 |
| T J S Services (Hull ) Ltd | Construction | 2014 |
| T Kidd NDT Limited | Professional & scientific | 2023 |
| T Mcphee Developments Ltd | Administrative & support | 2024 |
| T S & E Properties Ltd | Administrative & support | 2016 |