| Dotnet Ltd | Information & communication | 2019 |
| Dotties Desserts Blackpool Limited | Extraterritorial | 2021 |
| Dotties Desserts Ltd | Wholesale & retail | 2025 |
| Dotty & Mable Ltd | Wholesale & retail | 2024 |
| Double a Sorters Ltd | Other services | 2023 |
| Double the Trouble Limited | Hospitality | 2013 |
| Doubleyou Developments Ltd | Real estate | 2011 |
| Doubleyou Properties Limited | Hospitality | 2009 |
| Dovergen Limited | Construction | 2025 |
| Down & Swift Ltd | Wholesale & retail | 2025 |
| Downtime UK Grill Ltd | Hospitality | 2025 |
| Downtimer Ltd | Information & communication | 2021 |
| DP Support Ltd | Health & social care | 2022 |
| DPA Flooring Specialists Limited | Wholesale & retail | 2016 |
| DPG Group Ltd | Construction | 2022 |
| DPM Access Solutions Limited | Mining & quarrying | 2013 |
| DPM Security Management Ltd | Administrative & support | 2017 |
| DPN Copy Limited | Professional & scientific | 2019 |
| Dppn Property Ltd | Real estate | 2021 |
| DPR Electrical Ltd | Energy | 2019 |
| DPS Scaffolding N/W Limited | Construction | 2023 |
| DR Driveways Northwest Limited | Administrative & support | 2025 |
| DR Kagalwala and Company Ltd | Education | 2024 |
| DR Mechanics Ltd | Wholesale & retail | 2025 |
| DR Nidhi Aesthetics Ltd | Education | 2025 |
| DR Sophie Gordon Limited | Health & social care | 2012 |
| DR Yasmin Zeina Limited | Health & social care | 2026 |
| Dr.Simz Limited | Wholesale & retail | 2023 |
| Draco Power Limited | Construction | 2016 |
| Dragon Flare Marketing Limited | Financial services | 2024 |
| Dragon's Head Ltd | Information & communication | 2017 |
| Dream Clean Solutions Blackpool Ltd | Administrative & support | 2025 |
| Dreamcatcher Yachting Ltd | Extraterritorial | 2026 |
| Drek Solutions Ltd | Administrative & support | 2016 |
| Drekadu Ltd | Information & communication | 2025 |
| Driven Sports Car Hire Ltd | Professional & scientific | 2004 |
| Drone Surveys North West Ltd | Professional & scientific | 2025 |
| Droog Media Limited | Administrative & support | 2006 |
| DRR Holdings Ltd | Financial services | 2023 |
| Drrt Holdings Ltd | Financial services | 2026 |
| DRV Training Ltd | Information & communication | 2018 |
| Dryholme Biogas Limited | Energy | 2009 |
| DS Collins Ltd | Professional & scientific | 2017 |
| DS Consulting & Associates Limited | Administrative & support | 2015 |
| DS Finance Solution Ltd | Professional & scientific | 2024 |
| DS Lettings Agent Ltd | Real estate | 2025 |
| Dse&I Ltd | Construction | 2018 |
| DSG Groundworks and Civils Ltd | Construction | 2024 |
| DSG Property Development Ltd | Real estate | 2026 |
| DSH Consultancy Ltd | Information & communication | 2016 |
| Dshx Services Limited | Professional & scientific | 2025 |
| Dsnr Ltd | Professional & scientific | 2018 |
| Dsrobe Limited | Administrative & support | 2014 |
| DT Housing Ltd | Real estate | 2025 |
| DT Information Governance Ltd | Professional & scientific | 2019 |
| DT Inspection Ltd | Administrative & support | 2016 |
| DTH Care Ltd | Public administration | 2024 |
| DTM Holdings Limited | Financial services | 2020 |
| DTM Rentals Limited | Real estate | 2024 |
| Dual Sight Ltd | Administrative & support | 2026 |
| Dubai Investment Homes Ltd | Real estate | 2025 |
| Duchess Court (Blackpool) Limited | Households | 1959 |
| Duckworth Group Limited | Wholesale & retail | 2022 |
| Ducky's Electricians Ltd | Construction | 2025 |
| Duco Design Limited | Professional & scientific | 2019 |
| Duco Holdings Europe Limited | Professional & scientific | 2022 |
| Dudley Hotels Ltd | Hospitality | 2025 |
| Duelo Limited | Information & communication | 2025 |
| Duerden Couriers Limited | Transport & logistics | 2019 |
| Dugdale & Co Ltd | Hospitality | 2024 |
| Dugdale OIL Services Ltd | Other services | 2018 |
| Dunbia Solutions Limited | Wholesale & retail | 2025 |
| Dunbiar Ltd | Wholesale & retail | 2025 |
| Duncam Ltd | Construction | 2025 |
| Duncombe Springs Ltd | Wholesale & retail | 2025 |
| Dunemajor Limited | Professional & scientific | 1997 |
| Dunes Day Nursery & Pre-School Limited | Health & social care | 2016 |
| Dunes House Management Company Limited | Households | 2002 |
| Dungannon Partnership Ltd | Wholesale & retail | 2025 |
| Dunholme Neville Ltd | Wholesale & retail | 2025 |
| Dunlin Lodge Management Company Ltd | Households | 2000 |
| Dunlop Jacobs UK Ltd | Real estate | 2018 |
| Dunne & Co Investments Ltd | Financial services | 2021 |
| DUO FU House Limited | Hospitality | 2024 |
| Durban Court Limited | Households | 2000 |
| Durrocoat Limited | Professional & scientific | 2011 |
| Dutch Maid Ices (Blackpool) Limited | Manufacturing | 1997 |
| Dutton Court Management Limited | Households | 1990 |
| Duxbury Thomas Surveying Ltd | Administrative & support | 2022 |
| Duxbury's Group Limited | Professional & scientific | 2018 |
| Duxbury's Valuation Limited | Professional & scientific | 2009 |
| Duxburys Benstead Ltd | Real estate | 2020 |
| Duxburys Commercial Property Management Limited | Other services | 2026 |
| Duxburys Property Consultants Limited | Professional & scientific | 2013 |
| Duxburys Property Holdings Limited | Financial services | 2022 |
| DV Solutions Ltd | Manufacturing | 2019 |
| DW Data Solutions Ltd | Information & communication | 2012 |
| DW Insights Ltd | Information & communication | 2014 |
| DW Lettings Ltd | Real estate | 2019 |
| DW Maintenance Services Ltd | Other services | 2018 |