| Rutland Development & Construction Ltd | Construction | 2019 |
| RYE Hill Ltd | Wholesale & retail | 2020 |
| RYE Street Management Company Limited | Households | 2022 |
| RZ Paving Ltd | Construction | 2018 |
| S & G Medics Ltd | Health & social care | 2013 |
| S and B Property Group Limited | Real estate | 2022 |
| S&J Improvements Ltd | Construction | 2023 |
| S&O Interiors Ltd | Construction | 2025 |
| S&S Fire Safety Ltd | Public administration | 2022 |
| S.G. Warburg & Company Limited | Financial services | 2023 |
| S.P.C. (Technical Services) Ltd. | Construction | 1997 |
| S.Tyne Roofing Limited | Construction | 2019 |
| S3 JPM Ltd | Real estate | 2024 |
| Sabariyan Ltd | Real estate | 2024 |
| Sabetian Surveying Ltd | Professional & scientific | 2019 |
| Sabrosa Tapas Ltd | Hospitality | 2025 |
| Saenso Capital Ltd | Professional & scientific | 2020 |
| Safe and Sound Events Limited | Other services | 2016 |
| Safe Hands Electrical Limited | Construction | 2014 |
| Safeclear Environmental Solutions Ltd | Water & waste | 2025 |
| Safer Caring Ltd | Administrative & support | 2020 |
| Sage Heating Limited | Construction | 2016 |
| Sage Rural Limited | Education | 2013 |
| Saggers Ltd | Real estate | 2020 |
| Sahadevan & Co Limited | Professional & scientific | 2019 |
| Saint John Patrick Publishers Limited | Information & communication | 1994 |
| Salamelica Limited | Agriculture & fishing | 2015 |
| Sales Specialists Group Limited | Professional & scientific | 2026 |
| Salisbury Resources Limited | Construction | 2013 |
| Salitix Holdings Ltd | Financial services | 2020 |
| Salitix Ltd | Other services | 2011 |
| Salt Mountain Recruitment Limited | Administrative & support | 2023 |
| SAM & Ping Trading Ltd | Wholesale & retail | 2012 |
| SAM Miles Ltd | Information & communication | 2022 |
| Samantha Rosina Hopkins Limited | Extraterritorial | 2025 |
| Same Old Floors Limited | Construction | 2023 |
| Same Quality Developments Limited | Real estate | 2019 |
| Sanchez Does UX Ltd | Information & communication | 2023 |
| Sansarya Ltd | Hospitality | 2023 |
| Saphire Investment Ltd | Transport & logistics | 2026 |
| Sapphire QA Limited | Construction | 2022 |
| Sapphire Spinning Ltd | Manufacturing | 2009 |
| Sarah Townsend Editorial Limited | Professional & scientific | 2016 |
| SAS Living Group Ltd | Construction | 2025 |
| SAS Solar Ltd | Construction | 2023 |
| Sauceful Ltd | Information & communication | 2026 |
| Sawbridgeworth (River Court) Residents Association Limited | Households | 1984 |
| SB Transport Engineering Ltd | Professional & scientific | 2022 |
| SBK on the Go Ltd | Hospitality | 2025 |
| Sbmmarketing Limited | Professional & scientific | 2020 |
| Sbpj Property Ltd | Real estate | 2018 |
| SBT2 Ltd | Professional & scientific | 2020 |
| SC & a Properties Ltd | Real estate | 2025 |
| Scarlet Town Ltd | Financial services | 2013 |
| Schatunowski Brooks Limited | Real estate | 2019 |
| Schaye Limited | Financial services | 2025 |
| Schiplinc Limited | Health & social care | 2013 |
| Schoeman Contracts Ltd | Administrative & support | 2023 |
| Schoeman Renovations Ltd | Construction | 2022 |
| School Appeals Services LLP | | 2006 |
| School Staff Solutions Ltd | Administrative & support | 2015 |
| Schools With Altitude Limited | Education | 2018 |
| Schoolz OUT Ltd | Arts & recreation | 2026 |
| Science@Rabp Ltd | Professional & scientific | 2024 |
| Scientiareg Ltd | Professional & scientific | 2026 |
| Scientific L&D Consulting Limited | Professional & scientific | 2022 |
| Scinfos Limited | Administrative & support | 2019 |
| Scott Hewitt Electrical Services Limited | Construction | 2024 |
| Scott’S Boiler and Appliance Services Ltd | Other services | 2016 |
| Scribbled Heart Limited | Information & communication | 2016 |
| SCW Topco Limited | Financial services | 2024 |
| SCX Ltd | Financial services | 2022 |
| Sd-Asn Software Ltd | Information & communication | 2014 |
| Seamless Abutment Solutions Limited | Manufacturing | 2006 |
| Seamless Innovation Group Limited | Professional & scientific | 2021 |
| Seanan & Co Limited | Professional & scientific | 2020 |
| Search ETC. Ltd | Information & communication | 2024 |
| Searchtheory Ltd | Information & communication | 2024 |
| Seco Limited | Professional & scientific | 1986 |
| Second Harbinger Residents Association (Hampstead) Limited | Households | 1984 |
| Secondly Ltd | Wholesale & retail | 2024 |
| Security Facilities Management Limited | Administrative & support | 1992 |
| Seda Construction Limited | Construction | 2012 |
| Seemraj Properties Limited | Real estate | 2024 |
| SEG Solutions Limited | Professional & scientific | 2019 |
| Seiconoi Limited | Wholesale & retail | 2023 |
| Select Financial Services Limited | Professional & scientific | 2020 |
| Sell Sell Sell Ltd | Professional & scientific | 2006 |
| Sentinel Recovery Ltd | Transport & logistics | 2025 |
| Sentry Alarms Security Systems Limited | Administrative & support | 2000 |
| SEO2PRINT Ltd | Manufacturing | 2011 |
| Sergcars Limited | Transport & logistics | 2019 |
| Series Ltd | Administrative & support | 2020 |
| Series Ventures Ltd | Financial services | 2019 |
| Serverbytes Solutions Ltd. | Information & communication | 2012 |
| Service Productivity Consulting Ltd | Professional & scientific | 2022 |
| Seymor Growth Ltd | Professional & scientific | 2026 |
| SF Software Solutions Limited | Information & communication | 2019 |
| Shadow Heating Ltd | Financial services | 2025 |
| Shadow Industrial Ltd | Administrative & support | 2014 |