| Discover Amazing Ltd | Administrative & support | 2019 |
| Displaysense Ltd | Wholesale & retail | 1978 |
| Distinct Trading Ltd | Wholesale & retail | 2019 |
| Dixon & Co. Limited | Professional & scientific | 2003 |
| DJA Developments Limited | Construction | 2001 |
| Djconnie Ltd | Other services | 2022 |
| DJS Building & Carpentry Limited | Construction | 2018 |
| Dkml Limited | Arts & recreation | 2017 |
| Dmamaput Limited | Manufacturing | 2021 |
| DMG Delta Ltd | Administrative & support | 1996 |
| DMR & Sons Removals and Storage Ltd | Transport & logistics | 2022 |
| DN Adjusting Ltd | Financial services | 2015 |
| DN Consulting Services Limited | Administrative & support | 2018 |
| DN Legal Limited | Administrative & support | 2018 |
| DNR Civil Engineering Limited | Professional & scientific | 2015 |
| DO Words Good Ltd | Professional & scientific | 2021 |
| DOB74 Ltd | Wholesale & retail | 2019 |
| Doca Ltd | Professional & scientific | 2023 |
| Docka Industrial Doors Ltd | Construction | 2025 |
| Dog Days Dunmow Limited | Other services | 2017 |
| Dogramaci Properties Limited | Real estate | 2022 |
| Doig Psychology Ltd | Health & social care | 2018 |
| Doing Good Ltd | Other services | 2021 |
| Domeright Systems Limited | Information & communication | 1993 |
| Domino Productions Ltd | Arts & recreation | 2024 |
| Doors and Worktops Ltd | Manufacturing | 2020 |
| Doris Enterprises UK Limited | Hospitality | 2026 |
| Dosa Box Ltd | Hospitality | 2026 |
| Dosing Controls Ltd | Professional & scientific | 2021 |
| Double Barrel Engineering Ltd | Professional & scientific | 2021 |
| Dough&Co Bishops Stortford Limited | Hospitality | 2018 |
| Douglas Joshua Limited | Real estate | 2025 |
| Douglas Joshua Sales Limited | Real estate | 2026 |
| Dovecote Property Finance Ltd | Professional & scientific | 2021 |
| Dovedale Interiors Limited | Construction | 2014 |
| Downland Real Estate Limited | Real estate | 2024 |
| Downton Mortgages and Financial Services Ltd | Financial services | 2021 |
| DP Hotel Consultants Ltd | Professional & scientific | 2025 |
| DPB Renovations Limited | Construction | 2023 |
| DR a Michael Ltd | Health & social care | 2019 |
| DR C-Mac Ltd | Health & social care | 2026 |
| DR Holdings (BS) Limited | Real estate | 2017 |
| DR JO White Ltd | Education | 2022 |
| Dragonfly Connects Limited | Other services | 2020 |
| Dragonfly Wellness UK CIC | Wholesale & retail | 2022 |
| Drain Force and Plumbing Limited | Construction | 2025 |
| Drain TEQ Limited | Extraterritorial | 2010 |
| Drayton Distribution Services Limited | Transport & logistics | 1982 |
| Dreambridge Limited | Information & communication | 2024 |
| Dreamfocus Ltd | Information & communication | 2016 |
| Dreamlash London Ltd | Wholesale & retail | 2025 |
| Dri-Days Limited | Wholesale & retail | 2007 |
| Drinks Boutique Ltd | Wholesale & retail | 2020 |
| Dripaura Ltd | Health & social care | 2026 |
| DRIVEN2FITNESS Limited | Education | 2024 |
| Dryseal Basements Limited | Construction | 2021 |
| DS Accounting and Bookkeeping Ltd | Professional & scientific | 2024 |
| DS Social Group Ltd | Professional & scientific | 2024 |
| DSB Heating & Mechanical Services Ltd | Construction | 2015 |
| DT Bedroom Design Limited | Professional & scientific | 2006 |
| DT Pharma Services Ltd | Health & social care | 2020 |
| DT Realty & Investments Ltd | Real estate | 2025 |
| DUAL2 Ltd | Professional & scientific | 2012 |
| DUE NOW Payments Limited | Information & communication | 2026 |
| Dulwich Management & Letting Limited | Real estate | 1994 |
| Dunmow Diagnostic Service Ltd | Health & social care | 2022 |
| Dunmow Ironing Parlour Ltd | Other services | 2024 |
| Dunmow TKD Ltd | Information & communication | 2021 |
| Duro Custom Ltd | Wholesale & retail | 2021 |
| Dutton Engineering Project Services Limited | Construction | 2004 |
| DW Image Services Limited | Administrative & support | 2019 |
| DW Valet Ltd | Wholesale & retail | 2025 |
| Dwhite Mechanical Ltd | Construction | 2018 |
| Dynamic Ceilings & Partitions Ltd | Construction | 2022 |
| Dynamic Edge Limited | Wholesale & retail | 2023 |
| Dynamic Safeguarding Consultancy Ltd | Professional & scientific | 2023 |
| Dynamics Consultancy Limited | Wholesale & retail | 2013 |
| DZH Auto Ltd | Wholesale & retail | 2019 |
| E Stru Ltd | Information & communication | 2023 |
| E&E Locksmiths London Ltd. | Other services | 2015 |
| E&S Utilities Training Limited | Construction | 2024 |
| E-Seller Publishing Limited | Information & communication | 2011 |
| EAE Properties Limited | Real estate | 2024 |
| Eaglegate Recruitment Limited | Administrative & support | 2019 |
| EAO Mortgages Ltd | Financial services | 2024 |
| Early Birdie Golf Networking Ltd | Administrative & support | 2023 |
| Early Years EP Ltd | Health & social care | 2021 |
| Earth Natural Foods Limited | Wholesale & retail | 2006 |
| East Anglia Properties and Investments Ltd | Financial services | 2021 |
| East Anglian Removals Ltd | Transport & logistics | 2021 |
| East Coast Express Ltd | Wholesale & retail | 2021 |
| East Farm Developments Limited | Construction | 2023 |
| East Hertfordshire and Uttlesford Uniform Exchange CIC | Wholesale & retail | 2024 |
| East London Social Housing Limited | Administrative & support | 2010 |
| East MED Ltd | Professional & scientific | 2015 |
| Easy to DO Magic Ltd | Wholesale & retail | 2014 |
| EAT Drink Peach Limited | Hospitality | 2020 |
| EAT ME Caterers and Events Limited | Hospitality | 2026 |
| Eatery Junctions Limited | Hospitality | 2024 |
| Eaton's Seashells Limited | Wholesale & retail | 2003 |