| Pattinson Structural Design Limited | Administrative & support | 2014 |
| Paul Dorian Wealth Management Limited | Financial services | 2015 |
| Pavilion Bishop Auckland Ltd | Hospitality | 2025 |
| Pavilion Square (Phase 2) Management Company Limited | Real estate | 2017 |
| Pavilion Square (Pocklington) Management Company Limited | Households | 2015 |
| Pawsitively K9 Pet Services Ltd | Agriculture & fishing | 2026 |
| PBF Quality Consulting Ltd | Professional & scientific | 2014 |
| PD Property Maintenance Services Ltd | Administrative & support | 2025 |
| Peacegold CIC | Mining & quarrying | 2024 |
| Peacegold Trading Limited | Mining & quarrying | 2026 |
| Peak Performance Physiotherapy Ltd | Professional & scientific | 2022 |
| Peart Stone Limited | Manufacturing | 2025 |
| Peggottys Bakery Limited | Wholesale & retail | 2016 |
| Pentavia Development Ltd | Construction | 2025 |
| Percy Beck Farm LLP | | 2023 |
| Perfect Home and Garden Ltd | Wholesale & retail | 2006 |
| Perfect N.E. Profiles Limited | Construction | 2008 |
| Petals Florist Ltd | Wholesale & retail | 2018 |
| Peter G Smith Financial Consultancy Ltd | Professional & scientific | 2025 |
| Peter Lorimer Sports Limited | Wholesale & retail | 1976 |
| Peter Monkhouse Haulage LLP | | 2016 |
| PFR Industries Ltd | Construction | 2016 |
| PFS (Helston) Ltd | Professional & scientific | 2003 |
| Pharmatech Engineering Services Limited | Professional & scientific | 2002 |
| Phil Hodgson Ltd. | Other services | 2006 |
| Philip Tarren Limited | Construction | 1992 |
| Phoenix and Scoresby Park Management Company Limited | Households | 2014 |
| Phoenix Joinery Components Ltd | Manufacturing | 2021 |
| Phone Tech Revive Ltd | Wholesale & retail | 2023 |
| Picarsso Limited | Wholesale & retail | 2003 |
| Pick & Sweep Site Services Ltd | Administrative & support | 2026 |
| Pilkington Homes Limited | Real estate | 2014 |
| Pinfeather Collaborative Limited | Manufacturing | 2022 |
| Pinkney Building Contractors Limited | Construction | 2006 |
| Pinky Nail LUX Limited | Other services | 2025 |
| Pipstar Services Limited | Professional & scientific | 2021 |
| Pizza Crash Ltd | Hospitality | 2026 |
| Pizza Zone D Ltd | Hospitality | 2024 |
| Pizzart Auck Ltd | Wholesale & retail | 2025 |
| Pjhs Investments | Financial services | 2025 |
| Plastic Mouldings Northern Limited | Manufacturing | 2005 |
| Play Bond Ltd | Construction | 2022 |
| Plover Capital Limited | Professional & scientific | 2018 |
| Plus Beverages Ltd | Hospitality | 2023 |
| PM Consulting Engineers Limited | Professional & scientific | 2016 |
| PMN Holdings Limited | Financial services | 2022 |
| Polykeg UK Limited | Manufacturing | 2019 |
| Poppy Fields (Cottingham) Management Company Limited | Households | 2019 |
| Portable Appliance Testing Trade Association Limited | Other services | 2013 |
| Positive Future (Durham) Ltd | Education | 2019 |
| Potters-Ballotini Limited | Manufacturing | 1957 |
| Powa Automotive Ltd | Wholesale & retail | 2025 |
| Powerline Products Limited | Wholesale & retail | 2003 |
| PR Fibre Group Ltd | Information & communication | 2018 |
| Premier Community Care 2018 Limited | Financial services | 2018 |
| Premier Community Care Limited | Administrative & support | 2003 |
| Prep-Rite UK Flooring Services Ltd | Construction | 2011 |
| Prestige Clad Coatings Limited | Construction | 2015 |
| Prestige Roofing & Ground Work Ltd | Construction | 2025 |
| Primary Care Women's Health Forum Community Interest Company | Health & social care | 2013 |
| Primary Care Women's Health Society Community Interest Company | Health & social care | 2025 |
| Prime Chelsea Serviced Apartments Ltd | Real estate | 2017 |
| Prime Performance Physiotherapy Limited | Health & social care | 2018 |
| Prince Bishop Community Broadcasting Limited | Information & communication | 2007 |
| Princebishop Rendering Limited | Construction | 2014 |
| Princes Street Management Company (2011) Limited | Households | 2012 |
| Priscilla Tawamba Limited | Health & social care | 2016 |
| Pro Cargo Solutions Ltd | Transport & logistics | 2024 |
| Pro Fibre Solutions Ltd | Information & communication | 2022 |
| Procurement and Logistics Services Ltd | Transport & logistics | 2023 |
| Project 9 Automotive Ltd | Wholesale & retail | 2020 |
| Property Angel NE Ltd | Real estate | 2015 |
| Property GEN Ltd | Real estate | 2024 |
| Property Investments NE Ltd | Real estate | 2022 |
| Prospect Rise (Whitby) Management Company Limited | Households | 2018 |
| Prosperous Horizons Ltd | Professional & scientific | 2024 |
| Protech Northeast Ltd | Other services | 2024 |
| Protocol Design Solutions Limited | Administrative & support | 1997 |
| PRS Inclusion Consultancy Ltd | Professional & scientific | 2012 |
| PS Managed Solutions Limited | Water & waste | 2012 |
| Psychiatric Services - North East Limited | Health & social care | 2011 |
| Purkiss & Graham Property Ltd | Real estate | 2025 |
| Purple Rhino PR Ltd | Professional & scientific | 2013 |
| Puttingtons Limited | Administrative & support | 2022 |
| PVL Associates Ltd | Professional & scientific | 2016 |
| PWS Associates Limited | Professional & scientific | 2023 |
| Pyramid Architectural Design Limited | Construction | 2018 |
| Q-Dec Limited | Construction | 2014 |
| Q3 Developments Limited | Construction | 2014 |
| Quality Site Spraying Services Ltd | Manufacturing | 2023 |
| Quid Homes Limited | Real estate | 2025 |
| R & D (Durham) Limited | Construction | 2025 |
| R Davey Holdings Limited | Financial services | 2022 |
| R H Thompson Farming Ltd | Agriculture & fishing | 2017 |
| R Lightfoot Limited | Construction | 2004 |
| R W Shaw Properties Limited | Real estate | 2024 |
| R. a. White Transport Limited | Transport & logistics | 2016 |
| R.A. Dalton Limited | Water & waste | 2003 |
| R.A. Dalton Properties Limited | Real estate | 2015 |
| R.E.G. Groundworks Ltd | Construction | 2025 |