| Energize Solutions (Consulting) Ltd | Information & communication | 2023 |
| Energy Alliance Midlands Ltd | Professional & scientific | 2024 |
| Energy Bubble Limited | Administrative & support | 2022 |
| Energy Capital Midlands Ltd | Professional & scientific | 2025 |
| Energy Doctor Ltd | Administrative & support | 2016 |
| Energy Efficient Conservatories Ltd | Construction | 2023 |
| Energy Excellence Limited | Professional & scientific | 2025 |
| Energy GB Trading Under Prestige Business Services Ltd | Administrative & support | 2013 |
| Energy Geeks Ltd | Administrative & support | 2020 |
| Energy Help Limited | Professional & scientific | 2022 |
| Energy Network Events Limited | Administrative & support | 2019 |
| Energy Price Limited | Energy | 2021 |
| Energy PWR Limited | Wholesale & retail | 2025 |
| Energy PWR NFC Limited | Wholesale & retail | 2025 |
| Energy Saving Limited | Construction | 2023 |
| Energy Smart Consultancy Ltd | Energy | 2011 |
| Energy Steel Solutions Limited | Wholesale & retail | 2012 |
| Energy Stockholding Limited | Wholesale & retail | 2015 |
| Energy Systems Catapult Limited | Professional & scientific | 2013 |
| Energy Systems Catapult Services Limited | Professional & scientific | 2015 |
| Energy Tubes Limited | Manufacturing | 2003 |
| Energy VIA Limited | Administrative & support | 2017 |
| Energy VIA Sun Ltd. | Administrative & support | 2017 |
| Energy Watch Limited | Energy | 2017 |
| Energyefficientyou Ltd | Construction | 2012 |
| Energyui Limited | Administrative & support | 2021 |
| Enerserve Ltd | Professional & scientific | 2020 |
| Eness Group Ltd | Financial services | 2025 |
| ENF Capital Ltd | Real estate | 2025 |
| Enforcement City Limited | Administrative & support | 2021 |
| Enforcepif Ltd | Administrative & support | 2024 |
| Enforceright Ltd | Professional & scientific | 2021 |
| Engage Accountancy Limited | Professional & scientific | 2012 |
| Engage Business Group Limited | Financial services | 2023 |
| Engage Business Solutions Limited | Professional & scientific | 2022 |
| Engage Care Services Limited | Health & social care | 2020 |
| Engage Locums Ltd | Administrative & support | 2020 |
| Engage Transport Ltd | Extraterritorial | 2016 |
| Engage Wellbeing Ltd | Professional & scientific | 2022 |
| Engart Fans Limited | Professional & scientific | 1946 |
| Engelbrecht - Farben-Tapeten -Bodenbelaege- Limited | Administrative & support | 2004 |
| Engenex Ltd | Information & communication | 2020 |
| Engexco Limited | Manufacturing | 2021 |
| Engine Investments Limited | Other services | 2020 |
| Engine Training Consultancy Ltd | Professional & scientific | 2016 |
| Engineered by Zicam Ltd | Manufacturing | 2009 |
| Engineering and Welding Supplies Limited | Extraterritorial | 1964 |
| Engineering Auctions Limited | Wholesale & retail | 2021 |
| Engineering Design Services Limited | Construction | 2016 |
| Engineering Recruitment Solutions Global Ltd | Administrative & support | 2018 |
| Engineering Supply Chain Network Limited | Professional & scientific | 2011 |
| Engineeringtek Ltd | Professional & scientific | 2023 |
| Engineeringx Ltd | Professional & scientific | 2025 |
| Enginnov Construction Ltd | Professional & scientific | 2014 |
| Engionic Sales Ltd | Other services | 2025 |
| England & Wales Employment Advice Limited | Professional & scientific | 2017 |
| England Athletics Limited | Arts & recreation | 2005 |
| England Kerr Hands Solicitors Limited | Professional & scientific | 2009 |
| England-Murphy Consulting Ltd | Professional & scientific | 2026 |
| Englandchina Business Forum Limited | Other services | 2013 |
| Englands (Harborne) Limited | Real estate | 2009 |
| Englands Safety Limited | Manufacturing | 2009 |
| Englemed Ltd | Information & communication | 2009 |
| Englestede Properties Limited | Real estate | 1983 |
| Engleton Lane Ltd | Real estate | 2016 |
| English Chess Federation | Arts & recreation | 2004 |
| English Maths Science Tuition Centre Limited | Education | 2008 |
| English Solutions Services Limited | Administrative & support | 2021 |
| Engmal Holdings Limited | Financial services | 2019 |
| Engmal Stainless Limited | Wholesale & retail | 2019 |
| Engrave Masters Ltd | Wholesale & retail | 2024 |
| Enhance Business Strategies Limited | Professional & scientific | 2014 |
| Enhance Communications Limited | Professional & scientific | 1958 |
| Enhance Education Supply Ltd | Administrative & support | 2023 |
| Enhance Flooring Ltd | Construction | 2024 |
| Enhance Nails and Beauty Limited | Health & social care | 2007 |
| Enhance Salon Limited | Other services | 2025 |
| Enhanced by Mstee Ltd | Other services | 2023 |
| Enhanced Electrical Services Ltd | Construction | 2013 |
| Enhanced Smile Ltd | Health & social care | 2024 |
| Enhaul Limited | Transport & logistics | 2017 |
| Enhility Ltd | Transport & logistics | 2021 |
| Enigma Consultancy Coaching Services Ltd | Professional & scientific | 2014 |
| Enigma Consulting and Solutions Limited | Administrative & support | 2016 |
| Enigma Foods Ltd | Hospitality | 2025 |
| Enigma Housing (Nationwide) Ltd | Hospitality | 2026 |
| Enigma International Ltd | Administrative & support | 2020 |
| Enigma Marketing Limited | Professional & scientific | 2024 |
| Enigma Sporting Ltd | Wholesale & retail | 2024 |
| Enikkfrida Limited | Information & communication | 2023 |
| Enis Investments Limited | Real estate | 2024 |
| Enjoy Dining Card Ltd. | Professional & scientific | 2023 |
| Enjoy Dining Limited | Professional & scientific | 2019 |
| Enjoy Relocations Limited | Hospitality | 2021 |
| ENK Education Ltd | Education | 2017 |
| Enki Birmingham Ltd | Wholesale & retail | 2020 |
| Enlighten Group Limited | Health & social care | 2020 |
| Enlighten Services Ltd | Health & social care | 2026 |
| Enlightened Dreamer Limited | Professional & scientific | 2004 |
| Enlightzen Limited | Professional & scientific | 2020 |