| Designcover Limited | Professional & scientific | 1995 |
| Designcraft Studios Limited | Professional & scientific | 2025 |
| Designcreates Limited | Administrative & support | 2004 |
| Designed by Darkroom Ltd | Wholesale & retail | 2016 |
| Designeight Creative Ltd | Professional & scientific | 2025 |
| Designer Body's Limited | Administrative & support | 2017 |
| Designer Closet Global Limited | Wholesale & retail | 2019 |
| Designer Contracts Midlands Ltd | Wholesale & retail | 2025 |
| Designer Deals Limited | Wholesale & retail | 2023 |
| Designer Online Brands Limited | Wholesale & retail | 2021 |
| Designer Rack Pret Ltd | Wholesale & retail | 2023 |
| Designer Rack Studio Limited | Wholesale & retail | 2026 |
| Designer Surfaces UK Ltd | Construction | 2017 |
| Designers Suits Ltd | Wholesale & retail | 2024 |
| Designing Accessible Futures Together C.I.C. | Other services | 2025 |
| Designing Faces (UK) Ltd | Other services | 2017 |
| Designn Space Ltd | Wholesale & retail | 2022 |
| Designo Prints Ltd | Wholesale & retail | 2025 |
| Designs in Mind C.I.C. | Health & social care | 2005 |
| Desihousein Ltd | Transport & logistics | 2025 |
| Desire Claims & Hire Limited | Financial services | 2025 |
| Desire Cleaning Limited | Administrative & support | 2026 |
| Desire Community Hub Limited | Health & social care | 2022 |
| Desired Antiques and Interiors Ltd | Wholesale & retail | 2023 |
| Desired Care 4 U Ltd | Other services | 2012 |
| Desired Dream Ltd | Wholesale & retail | 2025 |
| Desirees Studio Ltd | Other services | 2014 |
| Desitravellersuk Ltd | Administrative & support | 2026 |
| Desk Heroes Ltd | Health & social care | 2025 |
| Deskbuddy Limited | Information & communication | 2022 |
| Desmond LN Ltd | Public administration | 2025 |
| Desserlo Foods Limited | Hospitality | 2021 |
| Dessert & Spice Limited | Hospitality | 2017 |
| Dessert Base Ltd | Hospitality | 2019 |
| Dessert Basket Limited | Hospitality | 2025 |
| Dessert Box 1 Ltd | Hospitality | 2025 |
| Dessert Boxx Ltd | Wholesale & retail | 2020 |
| Dessert Boxz Ltd | Hospitality | 2026 |
| Dessert DEN Limited | Hospitality | 2025 |
| Dessert Express (KH) Ltd | Hospitality | 2022 |
| Dessert Express + Ltd | Hospitality | 2025 |
| Dessert House Ltd | Hospitality | 2023 |
| Dessert LAB (Moseley) Ltd | Hospitality | 2022 |
| Dessert Magic Ltd | Hospitality | 2025 |
| Dessert Parlour Limited | Manufacturing | 2019 |
| Dessert Supplies Ltd | Hospitality | 2022 |
| Dessert Village Ltd | Wholesale & retail | 2020 |
| Dessert World and Burgers Limited | Hospitality | 2025 |
| Dessert World Limited | Hospitality | 2020 |
| DESSERT2 Ltd | Hospitality | 2025 |
| Desserthq Ltd | Hospitality | 2024 |
| Desserths Ltd | Hospitality | 2024 |
| Desserts 1271 Limited | Wholesale & retail | 2021 |
| Desserts 4 U Ltd | Hospitality | 2020 |
| Desserts Cafe Limited | Hospitality | 2025 |
| Desserts Deluxe Limited | Hospitality | 2024 |
| Desserts Stechford Limited | Hospitality | 2022 |
| Dessertz HUT Ltd | Hospitality | 2025 |
| Destaca Group Limited | Professional & scientific | 2023 |
| Destin Ltd | Real estate | 2025 |
| Destinata Property UK Limited | Real estate | 2016 |
| Destination Birmingham Ltd | Real estate | 2014 |
| Destined to WIN UK Ltd | Other services | 2017 |
| Destiney's Blinds Ltd | Manufacturing | 2012 |
| Destiny (Birmingham) Limited | Hospitality | 2019 |
| Destiny Corporate Limited | Real estate | 2026 |
| Destiny Events & Banqueting Suite Ltd | Hospitality | 2026 |
| Destiny Executive Travel Limited | Transport & logistics | 2025 |
| Destiny Homeless Housing Ltd | Real estate | 2017 |
| Destructive Devices Ltd | Manufacturing | 2023 |
| Detail C Ltd | Construction | 2013 |
| Detail Contract Cleaning Ltd | Administrative & support | 2025 |
| Detail DMC Ltd | Professional & scientific | 2012 |
| Detailing LAB Ltd | Wholesale & retail | 2024 |
| Details by Doctors Ltd | Health & social care | 2025 |
| Detecta Ltd. | Professional & scientific | 2022 |
| Determex Limited | | 1953 |
| Determination for Success Ltd | Administrative & support | 2023 |
| Dethusha Enterprises Ltd | Wholesale & retail | 2023 |
| Detoxology Ltd | Health & social care | 2026 |
| Detroit Style Pizza Ltd | Hospitality | 2026 |
| Deuxsentique Ltd | Manufacturing | 2025 |
| DEV Corporate Limited | Information & communication | 2025 |
| DEV Searchers Ltd | Administrative & support | 2026 |
| DEV Sync Ltd | Information & communication | 2025 |
| DEV Works Ltd | Information & communication | 2019 |
| DEV2GO Ltd | Information & communication | 2019 |
| Devan Homes Limited | Construction | 2005 |
| Devargas Hollenden Ltd | Wholesale & retail | 2025 |
| Devdrop Limited | Information & communication | 2007 |
| Develo Design Limited | Information & communication | 2013 |
| Develoop Group Limited | Information & communication | 2024 |
| Develop Enterprise & Business (DEB) Management & Consultancy Limited | Wholesale & retail | 2019 |
| Develop Happiness Ltd | Professional & scientific | 2019 |
| Developing Champions CIC | Education | 2026 |
| Development 3 Kingsbridge CST Ltd | Construction | 2018 |
| Development 5 Kingsbridge CST Ltd | Extraterritorial | 2018 |
| Development Care Ltd | Health & social care | 2020 |
| Development Construction Renovation Ltd | Construction | 2022 |
| Development in Social Enterprise CIC | Administrative & support | 2011 |