| DEO Property Lettings Limited | Real estate | 2016 |
| DEO U.K. Limited | Transport & logistics | 2023 |
| Deol 1 Ltd | Professional & scientific | 2016 |
| Deopa (UK) Ltd | Other services | 2023 |
| Deoxys Workshop Limited | Information & communication | 2023 |
| Depide Ltd | Wholesale & retail | 2022 |
| Depop IT Limited | Information & communication | 2014 |
| Depot Autos Limited | Wholesale & retail | 2024 |
| Depp Cafes Limited | Hospitality | 2025 |
| Depz Limited | Information & communication | 2024 |
| Dera MNA Limited | Hospitality | 2026 |
| Derad Ltd | Construction | 2017 |
| Derbridge Court Right to Manage Company Limited | Real estate | 2012 |
| Derby Delight Limited | Hospitality | 2023 |
| Derby Desserts Destiny Ltd | Hospitality | 2026 |
| Derby Driveways Limited | Construction | 2015 |
| Derc Clean Ltd | Transport & logistics | 2026 |
| Dere Resources Ltd | Wholesale & retail | 2016 |
| Dereham Court (Highwood) Management Company Limited | Households | 2022 |
| Derek Sach Associates Limited | Professional & scientific | 2015 |
| Derell Properties Limited | Real estate | 2008 |
| Derewals Motors Ltd | Wholesale & retail | 2017 |
| Derive Services Ltd | Administrative & support | 2022 |
| Derma Clinic Group Ltd | Health & social care | 2026 |
| Derma Co Skin Aesthestics Ltd | Other services | 2023 |
| Dermaky Ltd | Wholesale & retail | 2025 |
| Dermalign Skin & Laser Clinic Ltd | Other services | 2023 |
| Dermalogic Consultants Ltd | Health & social care | 2022 |
| Dermansouri Limited | Health & social care | 2015 |
| Dermaskills Academy Ltd | Wholesale & retail | 2022 |
| Dermatec Ltd | Other services | 2026 |
| Dermawoo Limited | Health & social care | 2017 |
| Dermawrap Limited | Health & social care | 2018 |
| Dermomedix Ltd. | Health & social care | 2008 |
| Dermoperfection Cosmetic Services Limited | Health & social care | 2015 |
| Dermoperfection Medical Ltd | Health & social care | 2022 |
| Dernier and Hamlyn Design Ltd | Manufacturing | 2020 |
| Derrick Gates Properties Limited | Real estate | 2025 |
| Derron Electrical Services Limited | Construction | 2003 |
| Derry Court Management Company Limited | Real estate | 2017 |
| Derry Suter Massage Clinic Limited | Other services | 2017 |
| Derston Ltd | Administrative & support | 2017 |
| Dervish Heritage Wear Ltd | Wholesale & retail | 2026 |
| Dervish Promotions Limited | Arts & recreation | 2003 |
| Derwent Works Management Company 1 Limited | Households | 2022 |
| Derwentwater | Financial services | 2021 |
| Derygate Limited | Administrative & support | 2022 |
| Desanech UK Ltd | Wholesale & retail | 2021 |
| Descant Productions Ltd | Information & communication | 2024 |
| Descartes Ltd | Manufacturing | 2025 |
| Descent Water Enterprises Limited | Extraterritorial | 2008 |
| Desert Energy UK Ltd | Mining & quarrying | 2025 |
| Desert Harbour UK Ltd | Real estate | 2023 |
| Desert Wave Tours Ltd | Other services | 2024 |
| Desh Corporation Limited | Wholesale & retail | 2018 |
| Deshi Khana Ltd | Hospitality | 2019 |
| Deshi Maas Bazaar Ltd | Wholesale & retail | 2018 |
| Deshi Scaffolding Services Ltd | Construction | 2025 |
| Desi Bites Kitchen Limited | Hospitality | 2025 |
| Desi Chatkharey Ltd | Hospitality | 2025 |
| Desi Cookery Ltd | Hospitality | 2021 |
| Desi Crave Co. Ltd | Hospitality | 2026 |
| Desi Dera Restaurant Limited | Hospitality | 2009 |
| Desi Dragon Limited | Hospitality | 2023 |
| Desi Fire Ltd | Hospitality | 2026 |
| Desi Flame Limited | Hospitality | 2019 |
| Desi Foods Birmingham Ltd | Hospitality | 2026 |
| Desi Nashta 2 Ltd | Hospitality | 2025 |
| Desi Parantha Corner Limited | Hospitality | 2020 |
| Desi Roti Khana Ltd | Hospitality | 2025 |
| Desi Spuds Limited | Hospitality | 2024 |
| Desi Stop Ltd | Hospitality | 2023 |
| Desi Venues & Estates Ltd | Construction | 2025 |
| Design & Build (Ullenhall) Ltd | Construction | 2020 |
| Design & Industries Association (the) | Education | 1944 |
| Design 2 Print (Llandudno) Limited | Manufacturing | 1991 |
| Design 2 Sail Ltd | Manufacturing | 2020 |
| Design and Deploy Limited | Information & communication | 2022 |
| Design and Plan Construction Limited | Professional & scientific | 2016 |
| Design Build 1 Ltd | Professional & scientific | 2013 |
| Design Building Ltd | Construction | 2016 |
| Design by Jack Ltd | Wholesale & retail | 2025 |
| Design Cars Ltd | Wholesale & retail | 2026 |
| Design Consultancy Pro Ltd | Professional & scientific | 2026 |
| Design Craft Interiors Ltd | Wholesale & retail | 2021 |
| Design Denim Limited | Wholesale & retail | 2008 |
| Design Engineering Pro Limited | Professional & scientific | 2017 |
| Design Inspiration to Build Limited | Construction | 2022 |
| Design NO Limits Ltd | Professional & scientific | 2023 |
| Design Pillars Ltd | Professional & scientific | 2025 |
| Design Planning Management Services UK Ltd | Other services | 2023 |
| Design Snitch Limited | Wholesale & retail | 2022 |
| Design Space 2 Ltd | Professional & scientific | 2012 |
| Design Studio 71 Ltd | Professional & scientific | 2023 |
| Design Tiling Ltd | Construction | 2026 |
| Design to Stitch Ltd | Manufacturing | 2018 |
| Design-Ex Ltd | Professional & scientific | 2018 |
| Design-Sg Limited | Administrative & support | 2010 |
| Design.Decode Ltd | Information & communication | 2023 |
| Designatech (B'Ham) Limited | Manufacturing | 1990 |