| Elite Business Brokers Ltd | Administrative & support | 2016 |
| Elite Developments Brickwork Specialists Ltd | Construction | 2026 |
| Elite Group LCA Limited | Administrative & support | 2017 |
| Elite Group LCA Office Supplies Limited | Other services | 2023 |
| Elite Group LCA Service Limited | Other services | 2023 |
| Elite Group LCA Solutions Limited | Other services | 2023 |
| Elite Group LIV UK Ltd | Wholesale & retail | 2025 |
| Elite Phones Limited | Wholesale & retail | 2013 |
| Elite Positive Progressions Limited | Other services | 2020 |
| Ellesmere Port Scaffolding Ltd | Construction | 2022 |
| ELM Court Property Management Company Limited | Households | 1989 |
| Elmwood Property Maintenance Limited | Construction | 2010 |
| Elvora Handling Limited | Wholesale & retail | 2025 |
| Elwoodinstallations-Uk Ltd | Manufacturing | 2026 |
| Elysian Inn Ltd | Real estate | 2025 |
| Emalex Investment Group Ltd | Real estate | 2026 |
| Emelec Limited | Construction | 2018 |
| Emergency Building Repairs Limited | Professional & scientific | 2023 |
| Emergency Role Allocation Systems Ltd | Information & communication | 2021 |
| Emergency Services Training Centre Ltd | Education | 2012 |
| Emst Ltd | Transport & logistics | 2008 |
| EMV Building Services Ltd | Construction | 2014 |
| Enabling Futures Ltd | Health & social care | 2010 |
| Encapsu Waste UK Limited | Water & waste | 2007 |
| Energy Efficiency Bidco Limited | Professional & scientific | 2024 |
| Energy Efficiency Midco Limited | Professional & scientific | 2024 |
| Energy Efficiency Topco Limited | Professional & scientific | 2024 |
| Enerlen Ltd | Administrative & support | 2022 |
| Enriched Financial Services Limited | Financial services | 2020 |
| Enterprises Inn Ltd | Real estate | 2025 |
| Environmental Revolution 5.0 Ltd | Manufacturing | 2018 |
| Epirus Dine in Ltd | Hospitality | 2025 |
| Epma (N.W) Limited | Wholesale & retail | 2009 |
| Equidata Solutions Limited | Information & communication | 2016 |
| Equipcare Ltd | Manufacturing | 2018 |
| Equita Limited | Administrative & support | 1996 |
| Equitable Holdings Limited | Administrative & support | 1988 |
| Ernest Thomas (Hendon) Limited | Wholesale & retail | 1953 |
| ES Device Ltd | Professional & scientific | 2026 |
| Escribe Europe Limited | Other services | 2003 |
| Essential Early Years Ltd | Education | 2019 |
| Essential Properties NW Ltd | Real estate | 2025 |
| Esther’S Compassionate Care Ltd | Health & social care | 2026 |
| Estrelinha Limited | Information & communication | 2025 |
| ETE Engineering Ltd | Professional & scientific | 2023 |
| Etec Engineering Systems Limited | Construction | 2013 |
| Etty Bay | Financial services | 2022 |
| Euro Carfix Garage Ltd | Wholesale & retail | 2023 |
| European Opera Centre | Education | 2015 |
| European Pre-Hospital Trauma Care Limited | Education | 2019 |
| EV Range Extender Ltd | Manufacturing | 2009 |
| Everclad Ltd | Construction | 2020 |
| Everything Enterprise Limited | Professional & scientific | 2011 |
| EVJ Consultancy Ltd | Professional & scientific | 2022 |
| Evolution Performance Cars (Wirral) Ltd | Wholesale & retail | 2020 |
| Evolve Complex Care Ltd | Administrative & support | 2016 |
| Evolve Contract Solutions Ltd | Professional & scientific | 2022 |
| Evolving Friendships Community Interest Company | Health & social care | 2026 |
| Evynra Ltd | Information & communication | 2026 |
| Excel Connect Solutions Ltd | Other services | 2013 |
| Excel Voice & Data Limited | Information & communication | 2017 |
| Excell Property Solutions Ltd | Construction | 2013 |
| Existential Investments Ltd | Financial services | 2021 |
| Exmouth Building Limited | Real estate | 2014 |
| Expedition Sports Group Limited | Manufacturing | 2016 |
| Exquisite Fitness Ltd | Wholesale & retail | 2025 |
| Ezee-Quit Wirral Ltd | Wholesale & retail | 2015 |
| F C Brown Limited | Construction | 2018 |
| FAB Caravan Rental Ltd | Hospitality | 2025 |
| Facade Systems Ltd | Construction | 2019 |
| Face Kandi Limited | Health & social care | 2018 |
| Fair ELK Properties Limited | Real estate | 2025 |
| Fairoak Consultancy Services Limited | Professional & scientific | 2014 |
| FAITH20 Care Ltd | Health & social care | 2020 |
| Faiveley Transport Birkenhead Limited | Manufacturing | 1984 |
| Faiveley Transport Tamworth Ltd | Manufacturing | 1993 |
| Falafel Alshaam Ltd | Manufacturing | 2024 |
| Families@Soul CIC | Education | 2023 |
| Family Hampers Limited | Professional & scientific | 1976 |
| Fantastic Nail (Birkenhead) Ltd | Other services | 2016 |
| Farm Fresh Meats Ltd | Wholesale & retail | 2024 |
| Fashionferaluk Ltd | Wholesale & retail | 2025 |
| FAT Lolly Sams Limited | Wholesale & retail | 2017 |
| Faulkner Group Ltd | Professional & scientific | 2024 |
| Faulkner Property Ltd | Real estate | 2023 |
| Fawkes Recruitment Ltd | Administrative & support | 2018 |
| Fazu Investments Limited | Hospitality | 2022 |
| FDA Properties Ltd | Real estate | 2019 |
| FE Caffe Birkenhead Ltd | Hospitality | 2023 |
| Fearnley Care Limited | | 1988 |
| Fenestration Solutions NW Limited | Manufacturing | 2019 |
| Fernwood Concepts Limited | Real estate | 2003 |
| Ferries Family Groups Ltd | Professional & scientific | 2008 |
| Ffact Limited | Other services | 2024 |
| Fibre Safe Limited | Other services | 2004 |
| Fifth GEN Recruitment Ltd | Administrative & support | 2019 |
| Figure IT OUT Ltd | Wholesale & retail | 2021 |
| Final Film Graphics Limited | | 1993 |
| Financial Risk Advisory Limited | Professional & scientific | 2008 |
| Fine Grocery Ltd | Wholesale & retail | 2022 |