| Rumaza Ltd | Administrative & support | 2023 |
| Rushby Resources Ltd | Construction | 2007 |
| Russell Royall Properties Limited | Real estate | 2017 |
| Russell Wright (Rushden) Ltd | Real estate | 2021 |
| Russell's Holdings Ltd | Real estate | 2017 |
| Russell's Partnership LLP | | 2017 |
| Rutherford Property Management Ltd | Hospitality | 2016 |
| RV Health Ltd | Health & social care | 2023 |
| RVS Retail Ltd | Wholesale & retail | 2024 |
| Rwhe Family Holdings Ltd | Real estate | 2023 |
| Rwhe Family Partnership LLP | | 2023 |
| Ryan a Deane Logistics Limited | Transport & logistics | 2025 |
| S & C Mcgivney WP Ltd | Administrative & support | 2024 |
| S & C Redmond WP Ltd | Administrative & support | 2024 |
| S & C Singh WP Ltd | Administrative & support | 2024 |
| S & M Huntridge WP Ltd | Administrative & support | 2024 |
| S & O OKE WP Ltd | Administrative & support | 2024 |
| S & R Drylining Ltd | Construction | 2019 |
| S 100 Lettings & Management Limited | Real estate | 2020 |
| S a R Care Recruitments Ltd | Administrative & support | 2026 |
| S a R Talent Innovation Limited | Professional & scientific | 2026 |
| S and S Family Partnership LLP | | 2020 |
| S Aristou WP Ltd | Professional & scientific | 2024 |
| S Bainbridge WP Ltd | Administrative & support | 2024 |
| S D Offshore Logistics Ltd | Construction | 2025 |
| S Edwards WP Ltd | Administrative & support | 2024 |
| S L Properties NE Ltd | Real estate | 2024 |
| S Paris WP Ltd | Administrative & support | 2024 |
| S Real WP Ltd | Administrative & support | 2024 |
| S Shaunak Holdings Limited | Real estate | 2019 |
| S Smith WP Ltd | Administrative & support | 2024 |
| S Taylor WP Ltd | Administrative & support | 2024 |
| S&D HK WP Ltd | Professional & scientific | 2024 |
| S&G Machining Ltd | Manufacturing | 2018 |
| S&G Services Teesside Limited | Construction | 2026 |
| S&I Developments Ltd | Construction | 2003 |
| S&S Walton WP Ltd | Administrative & support | 2024 |
| S&Sb Properties Limited | Real estate | 2024 |
| S&W Collective Ltd | Health & social care | 2026 |
| S.E. Decorators Limited | Construction | 1987 |
| S.P.H Financials Limited | Financial services | 2019 |
| S10 Projects Ltd | Professional & scientific | 2024 |
| Sablets Lettings Ltd | Real estate | 2025 |
| Sabre Insights Ltd | Professional & scientific | 2024 |
| Saddlestone West Limited | Real estate | 2013 |
| Safe Machine Limited | Professional & scientific | 2012 |
| Safe Stack Limited | Transport & logistics | 2025 |
| Saffiano Properties Ltd | Real estate | 2020 |
| Safiullah Family Holdings Ltd | Real estate | 2017 |
| Safiullah Family Partnership LLP | | 2017 |
| SAG Homes North West Limited | Real estate | 2025 |
| Sahota Pharma Limited | Health & social care | 2022 |
| Saint Mark Medical Limited | Health & social care | 2025 |
| Saint Michael Ltd | Health & social care | 2018 |
| Sairajvani Services Limited | Other services | 2021 |
| Saleem Memorial Trust UK | Extraterritorial | 2017 |
| Sales Affiliates Ltd | Administrative & support | 2016 |
| Sam's Kitchen & Function Rooms Limited | Hospitality | 2019 |
| Samdan Engineering Limited | Professional & scientific | 2014 |
| Samrina Family Holdings Ltd | Real estate | 2019 |
| Samrina Family Partnership LLP | | 2019 |
| Sanchez Resprays Ltd | Wholesale & retail | 2019 |
| Sanderson Health Ltd | Health & social care | 2023 |
| Santa's Coming to Town Ltd | Other services | 2023 |
| SAR Healthcare Ltd | Health & social care | 2024 |
| SAS 786 Properties Limited | Real estate | 2025 |
| Savor Estates Ltd | Real estate | 2020 |
| SC TEN Limited | Administrative & support | 2023 |
| Scce Ltd | Construction | 2000 |
| Schweizer Ltd | Real estate | 2023 |
| Scoh Inspection Limited | Mining & quarrying | 2011 |
| Scopus Investments Ltd | Financial services | 2022 |
| Scott Bros Refinishing Limited | Manufacturing | 2012 |
| Scott Bros. Enterprises Limited | Water & waste | 2003 |
| Scott Bros. Environmental Services Limited | Transport & logistics | 1995 |
| Scott Bros. Holdings Limited | Professional & scientific | 2003 |
| Scott Bros. Limited | Water & waste | 2007 |
| Scott Bros. Recycling Limited | Water & waste | 2003 |
| Sculley Property & Development Ltd | Real estate | 2025 |
| Sculpted Layers Ltd | Professional & scientific | 2023 |
| SDB Safety Ltd | Administrative & support | 2024 |
| Seal Coordinations Ltd | Mining & quarrying | 2025 |
| Sealedwithakissxo Ltd | Arts & recreation | 2024 |
| Seisbar Ltd | Hospitality | 2018 |
| Sellir Limited | Other services | 2014 |
| Senna V12 Bidco Limited | Professional & scientific | 2025 |
| Senna V12 Topco Limited | Professional & scientific | 2025 |
| Sequoia Generations LLP | | 2022 |
| Servace Solutions Limited | Administrative & support | 2006 |
| Servertron Limited | Information & communication | 2012 |
| SEVENTY7 Property Development (North Shields) Limited | Real estate | 2024 |
| Sewail Ltd | Hospitality | 2025 |
| SF Estate Group Ltd | Real estate | 2025 |
| SF Hauliers Limited | Other services | 2010 |
| SG Welding & Fabrications Ltd | Manufacturing | 2019 |
| SHA Medical Services Ltd | Health & social care | 2026 |
| Shailer Properties Partnership LLP | | 2020 |
| Shailer Property Ltd | Real estate | 2020 |
| Shalimar Tandoori Ltd | Hospitality | 2025 |
| Shamim Family Holdings Limited | Real estate | 2021 |