| PM Insulation Services Ltd | Construction | 2025 |
| Pollit Rental Ltd | Real estate | 2022 |
| Pollyfields Limited | Wholesale & retail | 2019 |
| Polymath Professional Solutions Ltd | Administrative & support | 2019 |
| Popeks Car Polish Limited | Wholesale & retail | 2021 |
| Poppy Field Close Management Company Limited | Real estate | 2018 |
| Portable Sanitation Europe Limited | Other services | 1999 |
| Porthouse Technical Services Limited | Information & communication | 2014 |
| Portmellon Ltd | Hospitality | 2016 |
| Posh Wash of Bideford Ltd | Other services | 2015 |
| POW Furnishings Limited | Real estate | 1963 |
| Powell Enterprise Group Limited | Financial services | 2019 |
| Powerhouse Studios Bideford Ltd | Arts & recreation | 2022 |
| Powlers Piece Park Ltd | Construction | 2019 |
| PPW Design Limited | Administrative & support | 2007 |
| Prance Motor Services Ltd | Wholesale & retail | 2010 |
| Prconsulting (SW) Limited | Professional & scientific | 2018 |
| Precision Plumbing and Heating Solutions Ltd | Construction | 2018 |
| Preece Holdings Limited | Financial services | 2025 |
| Pridham Place Management Company Limited | Real estate | 2019 |
| Prime Heat Devon Ltd | Construction | 2025 |
| Prints Regent Press Limited | Manufacturing | 2021 |
| Probus Consultancy Ltd | Professional & scientific | 2019 |
| Product Assessment and Reliability Centre Limited | Professional & scientific | 1999 |
| Profile Manufacturing South West Limited | Manufacturing | 2002 |
| PT Psychotherapy Limited | Health & social care | 2021 |
| Puffin Court Management Company Ltd | Households | 2010 |
| Pump Rescue LLP | | 2010 |
| Pure Commercial Holdings Ltd | Real estate | 2026 |
| Pure Rend Limited | Construction | 2025 |
| PVF Scaffolding Ltd | Professional & scientific | 2014 |
| Q & S Distilling Co Ltd | Manufacturing | 2017 |
| Q Homes (Clifton Street) Limited | Construction | 2024 |
| Quate Ltd | Administrative & support | 2021 |
| Quay Cars Ltd | Transport & logistics | 2012 |
| Quay Garage and Car Sales Ltd | Wholesale & retail | 2018 |
| Quay Movement Limited | Other services | 2020 |
| Quayside Holidays Ltd | Hospitality | 2017 |
| Queen Annes Dental Practice Limited | Health & social care | 2007 |
| R & C H Wilson Builder Limited | Construction | 2003 |
| R & D Water Engineers Limited | Professional & scientific | 2010 |
| R a Jeffery Ltd | Professional & scientific | 2025 |
| R and a Williams Ltd | Wholesale & retail | 2001 |
| R K & S M Heard Limited | Agriculture & fishing | 2005 |
| Rabdon Limited | Extraterritorial | 2016 |
| Raccoon Investment Holdings Limited | Hospitality | 2017 |
| Raccoon Property Services Limited | Real estate | 2019 |
| Rachel Whale Consultancy Ltd | Professional & scientific | 2026 |
| RAE and Co Trading Ltd | Other services | 2016 |
| Rakcna Media Ltd | Arts & recreation | 2018 |
| Rapid Marine Limited | Wholesale & retail | 2013 |
| Rare Financial Ltd | Professional & scientific | 2023 |
| RAT Solutions Limited | Mining & quarrying | 2012 |
| RB Outdoors UK Ltd | Education | 2024 |
| RD Construction SW Ltd | Construction | 2020 |
| RDB Electrical Limited | Construction | 2003 |
| RDC Electrical Ltd | Construction | 2021 |
| Really Wild Planet CIC | Education | 2020 |
| Red Brick Training & Consulting Ltd | Information & communication | 2014 |
| Red Devon Ventures Limited | Professional & scientific | 2011 |
| Red Herring Productions CIC | Arts & recreation | 2013 |
| Redcliff Estates Limited | Construction | 2000 |
| Redcliffe Legal Limited | Administrative & support | 2026 |
| Reinhardt Media Ltd | Information & communication | 2014 |
| Remix Bait Ltd | Wholesale & retail | 2024 |
| Renatus Limited | Manufacturing | 2000 |
| Renov X Ltd | Construction | 2024 |
| Rent 'N' Ride Bike Rentals Limited | Administrative & support | 2024 |
| RESIN8COMMUNICATION Ltd | Information & communication | 2025 |
| Revanp Conversions Ltd | Wholesale & retail | 2021 |
| Rich Tech Services Limited | Information & communication | 2019 |
| Richmond Offshore Energy Ltd | Energy | 2023 |
| Richmond Properties (Hartland) Limited | Real estate | 1997 |
| Ride the Wave Bookkeeping Ltd | Professional & scientific | 2023 |
| Ridges Transport MOT & Service Centre Ltd | Wholesale & retail | 2026 |
| Riding to the Anchor Ltd | Hospitality | 2019 |
| Right Surveyors Asset Management Ltd | Professional & scientific | 2013 |
| Right Surveyors Ltd | Professional & scientific | 2011 |
| Rightangle (SW) Limited | Professional & scientific | 2019 |
| Riverbank Care Limited | Health & social care | 2001 |
| Riverside Auto Services Limited | Wholesale & retail | 2008 |
| Riverside Engineering SW Ltd | Manufacturing | 2016 |
| Riverside Flats Management Company Limited | Households | 2024 |
| Rjfw Engineering Solutions Ltd | Professional & scientific | 2018 |
| RJO Lighting Ltd | Construction | 2023 |
| RK Telecoms Limited | Information & communication | 2016 |
| RLR Construction (South West) Ltd | Construction | 2016 |
| RM Cattle Imports Limited | Wholesale & retail | 2015 |
| RM Software Services Ltd | Information & communication | 2019 |
| RMZ Management Limited | Construction | 2016 |
| Road Song Books Ltd | Information & communication | 2026 |
| ROB Blackmore Heating Services Limited | Manufacturing | 2004 |
| Robert & Gordon Associates Ltd | Professional & scientific | 2020 |
| Robin Hill Farm Cottages Limited | Hospitality | 2022 |
| Robins Plant Ltd | Administrative & support | 2016 |
| Robinsons Garage Limited | Wholesale & retail | 2004 |
| ROD 76 Limited | Hospitality | 2011 |
| Roju Limited | Wholesale & retail | 2022 |
| Rolle Canal Company Ltd | Professional & scientific | 2008 |
| Rolle Freight Limited | Transport & logistics | 2016 |