| David Munns and Company Limited | Administrative & support | 1984 |
| David Rolfe Limited | Information & communication | 2007 |
| David Sanderson Property Ltd | Real estate | 2023 |
| Davidliz Limited | Hospitality | 2021 |
| DBS Group Holdings Co. Ltd | Financial services | 2021 |
| DC BRT Transport Ltd | Transport & logistics | 2020 |
| DD26 Limited | Professional & scientific | 2013 |
| Ddpi Investment Properties Ltd | Real estate | 2020 |
| DE BRY Rare Books Limited | Wholesale & retail | 2023 |
| Deanpast Limited | | 1909 |
| Deans Court Newsagents Limited | | 1990 |
| Dear Debra Limited | Professional & scientific | 2022 |
| Debabool Consult Ltd | Information & communication | 2026 |
| Deborah Cooper Limited | Professional & scientific | 2011 |
| Deborah Reynolds Interiors Limited | Administrative & support | 2008 |
| Debt Relief International Limited | Information & communication | 1997 |
| Deeley Property Management Ltd | Households | 2019 |
| Deepbludirect Ltd | Wholesale & retail | 2019 |
| Defence Technology Enterprises Limited | Professional & scientific | 1984 |
| Defined Vector Design Limited | Wholesale & retail | 2023 |
| Deko Dental Laboratory Limited | Other services | 2014 |
| Delistop Ltd | Hospitality | 2019 |
| Della Luce Limited | Professional & scientific | 2012 |
| Delp Group Limited | Transport & logistics | 2021 |
| Delta Laundry Services Ltd | Professional & scientific | 2010 |
| Delta Printing Ltd | Professional & scientific | 2022 |
| Delta Technology Solutions Ltd | Wholesale & retail | 2019 |
| Denco Advisory Ltd | Professional & scientific | 2018 |
| Dene Valley Training Limited | Administrative & support | 2015 |
| Denise Care Limited | Health & social care | 2019 |
| Denridge Engineering Limited | Professional & scientific | 2002 |
| Dentan Property Ltd | Real estate | 2025 |
| Dentistry @ the Old Bank Limited | Health & social care | 2022 |
| Denton Building Contractors Limited | Construction | 2010 |
| Dentoworld Ltd | Health & social care | 2020 |
| Denys Farm Ltd | Construction | 2012 |
| Dermcodes Limited | Health & social care | 2024 |
| Desi Style Kitchen Ltd | Hospitality | 2019 |
| Design 2F Limited | Extraterritorial | 2013 |
| Development Finance International Ltd. | Information & communication | 2001 |
| Devivd Regulatory Solutions Limited | Professional & scientific | 2020 |
| DG Electrical Design Consultancy Limited | Construction | 2014 |
| DG WIN Ltd | Professional & scientific | 2020 |
| Dgfu Renewables Limited | Professional & scientific | 2021 |
| DGH Manufacturing Ltd | Manufacturing | 2014 |
| Dgym Limited | Professional & scientific | 2010 |
| Dhillon Real Estates Limited | Real estate | 2016 |
| DHL Properties Bicester Ltd | Households | 2017 |
| Diamond Nails North Limited | Other services | 2019 |
| Dibbles Auto Shop Limited | Wholesale & retail | 2011 |
| Dibvelinov Limited | Administrative & support | 2022 |
| Dick Wise & Co,Limited | Construction | 1959 |
| Digi Gbox Limited | Professional & scientific | 2015 |
| Digital Accounting Enterprises Ltd | Professional & scientific | 2018 |
| Digital Presence Ltd | Information & communication | 2024 |
| Digital Visionaries Ltd | Professional & scientific | 2025 |
| Diligent Wills & Estate Planning Limited | Other services | 2026 |
| Dimov Building Limited | Construction | 2026 |
| Dimov Main Supply Ltd | Wholesale & retail | 2026 |
| Direct Technology Solutions Limited | Manufacturing | 2013 |
| Discount Cars & Recovery Ltd | Wholesale & retail | 2024 |
| Distinct Events Limited | Administrative & support | 2025 |
| Distinct Solutions Ltd | Administrative & support | 2003 |
| Dittapro Ltd | Wholesale & retail | 2016 |
| Divine Auto Restorations Ltd | Wholesale & retail | 2022 |
| DJ & RJ Holdings Limited | Real estate | 2020 |
| DJA International Legal Consultancy Services Limited | Professional & scientific | 2020 |
| DJT Builders Oxfordshire Limited | Construction | 2014 |
| DLZ Developments Limited | Real estate | 2026 |
| DMB Project Consulting Ltd | Professional & scientific | 2023 |
| DMD Group Ltd | Administrative & support | 2019 |
| DMD Haulage Limited | Transport & logistics | 2024 |
| DMD Transport Solutions Ltd | Transport & logistics | 2026 |
| Dmdi UK | Other services | 2026 |
| Dmfences Ltd | Manufacturing | 2015 |
| DMG Partnership Limited | Professional & scientific | 2016 |
| DNE Trading UK Limited | Administrative & support | 2012 |
| DOC Squiffy Limited | Information & communication | 2023 |
| Doctorpharma Ltd | Agriculture & fishing | 2021 |
| Dog Hair State Limited | Information & communication | 2014 |
| Dojebet Unlimited | Financial services | 2026 |
| Dojo Sports Ltd | Education | 2018 |
| Domus Leaseholders Limited | Real estate | 2012 |
| Dorchester (Heyford Park) LLP | | 2009 |
| Dorchester Living Limited | Construction | 2013 |
| Dorchester Phase 5 Ltd | Construction | 2025 |
| Dorchester Settlements Limited | Professional & scientific | 2009 |
| Doughboys Pizza Ltd | Hospitality | 2025 |
| DR Emily Prpa Limited | Health & social care | 2026 |
| DR Farah Ramjohn Limited | Health & social care | 2022 |
| DR Moncrieff Medical Ltd | Health & social care | 2016 |
| DR Natalie Aesthetic Training Ltd | Administrative & support | 2021 |
| DR Nick Ltd | Health & social care | 2022 |
| Dragon Brick Holdings Limited | Construction | 2020 |
| Dragonfly Framing Limited | Other services | 2020 |
| Dragonfly Fulfillment Ltd | Wholesale & retail | 2024 |
| Dragonfly Groomswear Limited | Administrative & support | 2021 |
| Dragonfly Water Consultancy Limited | Professional & scientific | 2018 |
| Dragonvault Ltd | Wholesale & retail | 2025 |
| Drain Clear Services Limited | Construction | 2002 |