| Rose Pound Ltd | Wholesale & retail | 2026 |
| Rosella Management Ltd | Real estate | 2012 |
| Rotherhithe Lifting Solutions Limited | Construction | 2012 |
| Routfree Limited | Information & communication | 2025 |
| ROV Holdings Limited | Real estate | 2023 |
| Roveclothing Ltd | Wholesale & retail | 2025 |
| Royale Tanning & Beauty Ltd | Other services | 2024 |
| Royce Innovation Ltd | Manufacturing | 2016 |
| RPD Consulting Ltd | Professional & scientific | 2020 |
| RPD Pharma Ltd | Wholesale & retail | 2020 |
| Rpsa Property Investments Ltd | Real estate | 2021 |
| RR Investments and Lettings Limited | Real estate | 2020 |
| RS Global London Ltd | Real estate | 2024 |
| RS Technologies Services Ltd | Information & communication | 2024 |
| RSR Properties 2000 Limited | Real estate | 2020 |
| RTC Corp Ltd | Manufacturing | 2023 |
| RTC Resources Limited | Administrative & support | 2019 |
| Rugiatu KAY K Empire (RKK Empire) Ltd | Professional & scientific | 2018 |
| RUNE10 Limited | Professional & scientific | 2015 |
| Rupeiks Ltd | Transport & logistics | 2020 |
| Rush Marketing Ltd | Wholesale & retail | 2000 |
| Rushdon Investments Limited | Real estate | 2023 |
| Russells Roofing Service Ltd | Construction | 2022 |
| RW Transport Consultancy Ltd | Professional & scientific | 2026 |
| S & G Patel Limited | Wholesale & retail | 2019 |
| S B N Welding Ltd | Other services | 2025 |
| S Wilkinson Fibre Limited | Information & communication | 2023 |
| S&H Bros Investment Ltd | Real estate | 2024 |
| S&J Logistics Ltd | Transport & logistics | 2024 |
| S.C.O Management Ltd | Administrative & support | 2022 |
| S.I.P Electrical Services Ltd | Energy | 2015 |
| S.K.D Sidcup Limited | Construction | 2017 |
| S.K.D Welling Limited | Construction | 2017 |
| S7 GAH Ltd | Professional & scientific | 2024 |
| SAA Autos Ltd | Wholesale & retail | 2025 |
| Sabina Hair Cosmetics (DA6) Ltd | Wholesale & retail | 2022 |
| Saeed Transport Limited | Transport & logistics | 2025 |
| SAF Properties London Ltd | Real estate | 2020 |
| Safa UK Foods Ltd | Administrative & support | 2017 |
| SAI Baba Regulatory Reporting Limited | Professional & scientific | 2026 |
| SAI Residential Ltd | Real estate | 2025 |
| Salli Kids Limited | Education | 2023 |
| SAM Burkey Ltd | Arts & recreation | 2025 |
| Samnotra Properties Limited | Real estate | 2020 |
| Samri Bottle Stop Ltd | Wholesale & retail | 2020 |
| Samsara (UK) Limited | Wholesale & retail | 2004 |
| Sanctorum Limited | Real estate | 2026 |
| Sandedan Limited | Information & communication | 2017 |
| Sandford Motors Limited | Administrative & support | 2024 |
| Sandra Sheikh Consultancy Limited | Professional & scientific | 2019 |
| Sandwich Belvedere Limited | Hospitality | 2026 |
| Sanford Meditravel UK Limited | Administrative & support | 2022 |
| Sanford Trading UK Limited | Wholesale & retail | 2022 |
| Santa Barbara Properties Limited | Real estate | 2001 |
| Santsabi Ltd | Wholesale & retail | 2020 |
| SAP Config Team Limited | Information & communication | 2009 |
| Sara & ZEE Ltd | Wholesale & retail | 2019 |
| Sara Pearce Fine Art Limited | Wholesale & retail | 2014 |
| Sarah's Boutique Limited | Health & social care | 2014 |
| Sardar Prop Limited | Real estate | 2016 |
| Saroc Investments Limited | Wholesale & retail | 2019 |
| SBR Building Contractors Ltd | Construction | 2016 |
| Scarlett's Agency Limited | Real estate | 2016 |
| Sccb Building Services Limited | Construction | 2017 |
| Schnipper Technology Ltd | Information & communication | 2015 |
| SCL Property Services Ltd | Real estate | 2026 |
| Scott's and Sons Ltd | Households | 2021 |
| Scrambles Heating and Cooling Ltd | Construction | 2023 |
| Scrumly Ltd | Information & communication | 2022 |
| SCS Screeding Ltd | Construction | 2022 |
| SD Vision Building Contractors Limited | Construction | 2025 |
| SDK Property Management Ltd | Real estate | 2021 |
| SDP Clean Limited | Other services | 2025 |
| Season Fresh Ltd | Wholesale & retail | 2020 |
| Seatrust Shipping Services Limited | Transport & logistics | 2023 |
| Secret Doors Music Limited | Information & communication | 1986 |
| Seda (London) Limited | Hospitality | 2011 |
| Seelukas Ltd | Real estate | 2018 |
| Seem Electrical Ltd | Manufacturing | 2023 |
| Segin Limited | Information & communication | 2021 |
| Segs Logistics Limited | Transport & logistics | 2025 |
| Sehajestates Ltd | Real estate | 2024 |
| SEJ Construction Ltd | Construction | 2024 |
| Seker Limited | Hospitality | 2025 |
| Selayang Ltd | Hospitality | 2020 |
| Selena GAS Domestic Services Ltd | Construction | 2015 |
| Sellick Holdings Company Ltd | Financial services | 2025 |
| Selltouk Ltd | Wholesale & retail | 2026 |
| Selnur Ltd | Hospitality | 2017 |
| Semoorg Building & Maintenance Limited | Construction | 2025 |
| Send Specialist Services Ltd | Education | 2024 |
| Sense Recruitment Ltd | Administrative & support | 2026 |
| Sentient Cities Ltd | Information & communication | 2026 |
| Serene Haven Care Home Ltd | Health & social care | 2025 |
| Serene Touch Care Services Ltd | Professional & scientific | 2025 |
| Seven Eight Construction Ltd | Construction | 2025 |
| Seychelles London Ltd | Wholesale & retail | 2021 |
| SF Change Consulting Ltd | Information & communication | 2023 |
| SFI Services Ltd | Professional & scientific | 2026 |
| SGJ Estates Ltd | Real estate | 2025 |