| ST Michaels Events Limited | Arts & recreation | 2017 |
| ST Pauls Management Advisory Limited | Professional & scientific | 2017 |
| ST Raphaels Basingstoke Management Limited | Households | 2006 |
| ST Thomas Court (Pagham) M.C. Limited | Households | 2002 |
| Staaaandard Ltd | Professional & scientific | 2020 |
| Staam Systems Limited | Information & communication | 2018 |
| Stable Development Ltd | Real estate | 2026 |
| Stable Yard Garden Company Limited | Households | 2012 |
| Staged Events Ltd | Administrative & support | 2013 |
| Stallion Heights Lifecare Group Ltd | Health & social care | 2025 |
| Stampsorted Ltd | Information & communication | 2026 |
| Standen Consulting Limited | Construction | 2026 |
| Stanley & Co Accountancy Limited | Professional & scientific | 2026 |
| Stanleys Coffee Shop Ltd | Hospitality | 2024 |
| Stanton Financial Consulting Ltd | Professional & scientific | 2021 |
| Stanviewhomes Ltd | Real estate | 2025 |
| Star Helps Ltd | Health & social care | 2026 |
| Star Paws Limited | Extraterritorial | 2021 |
| Staride Limited | Other services | 2019 |
| Starlight Hygienist Ltd | Health & social care | 2019 |
| Starlight Stage School Ltd | Arts & recreation | 2019 |
| Starswitch Consultants Ltd | Information & communication | 2018 |
| Starswitch Investments Ltd | Real estate | 2018 |
| Starswitch Solutions Ltd | Information & communication | 2014 |
| Start ME UP Ltd | Education | 2015 |
| Starwrick Care Limited | Administrative & support | 2022 |
| Statera Libera Ltd | Information & communication | 2024 |
| Stateside Soccer Limited | Education | 2025 |
| Stay Basingstoke Limited | Real estate | 2023 |
| Stay Management Ltd | Real estate | 2023 |
| Stay With ME Ltd | Hospitality | 2022 |
| Staywell Care Ltd | Health & social care | 2026 |
| STE UK Holdco Limited | Financial services | 2017 |
| STE UK SUB Holdco Limited | Financial services | 2017 |
| Steadhold Properties Ltd | Real estate | 2026 |
| Steadwell Systems Ltd | Administrative & support | 2026 |
| Stellar Business Support Ltd | Administrative & support | 2020 |
| STELLAR360 Limited | Administrative & support | 2023 |
| Stelvio Creative Ltd | Arts & recreation | 2016 |
| Stephen Nathans and Sons Limited | Administrative & support | 2023 |
| Stephenson Tilley Ltd | Professional & scientific | 2014 |
| Stephensons Enterprise Fork Trucks Limited | Extraterritorial | 2000 |
| Steris CH Limited | Financial services | 2003 |
| Steris Dover AST Holdings Limited | Financial services | 2018 |
| Steris Dover Canada Holdings Limited | Financial services | 2018 |
| Steris Dover Limited | Financial services | 2018 |
| Steris IMS Limited | Manufacturing | 1982 |
| Steris Limited | Financial services | 2014 |
| Steris UK Holding Limited | Financial services | 2014 |
| Sterling House (Freehold) Management Company Ltd | Households | 2017 |
| Sterling House Financial Management Limited | Financial services | 2025 |
| Sterling House Wealth Management Limited | Financial services | 2026 |
| Sterling Investment Ventures Ltd | Real estate | 2020 |
| Sterling Mechanical Handling Limited | Extraterritorial | 1986 |
| Sterling Mortgage Advice Ltd | Financial services | 2020 |
| Stermol Logistic Ltd | Transport & logistics | 2022 |
| Sternak Limited | Transport & logistics | 2018 |
| Steve Conway Ltd | Arts & recreation | 2014 |
| Steve Dale Limited | Information & communication | 2015 |
| Steve Scaffolding Hampshire Ltd | Construction | 2026 |
| Stevens IT Solutions Limited | Information & communication | 2020 |
| Steve’S GRP and Composites Ltd | Manufacturing | 2021 |
| Stichwork Ltd | Manufacturing | 2024 |
| Stickerscape Limited | Manufacturing | 2012 |
| Stickland Plumbing & Heating Ltd | Construction | 2019 |
| Stigant IT Ltd | Information & communication | 2020 |
| Still Waters Organisation Limited | Manufacturing | 2021 |
| Stkjet Limited | Other services | 2025 |
| Stock Emporium Limited | Wholesale & retail | 2023 |
| Stockpiece Limited | Administrative & support | 2002 |
| Stokes Structures Limited | Professional & scientific | 2017 |
| Stomax Limited | Wholesale & retail | 2025 |
| Stonefield Design Limited | Construction | 2010 |
| Stonefront Ltd | Construction | 2025 |
| Stoneybrook Investments Limited | Real estate | 2017 |
| Storacall Technology (Corporate Trustee) Limited | Information & communication | 2017 |
| Storck Travel Retail Limited | Professional & scientific | 1988 |
| Storck UK Limited | Manufacturing | 1969 |
| Stow Sports School Limited | Education | 2023 |
| Strange Turns Records Ltd | Wholesale & retail | 2025 |
| Strapack UK Limited | Professional & scientific | 1995 |
| Stratfield Road Dental Practice Limited | Health & social care | 2008 |
| Stratis Components Ltd | Wholesale & retail | 2025 |
| Stratos Management Consulting Ltd | Professional & scientific | 2011 |
| Stratton Property Investments Ltd | Extraterritorial | 2019 |
| Strattons Limited | Professional & scientific | 1964 |
| Stratumiq Ltd | Information & communication | 2025 |
| Streakwise Limited | Administrative & support | 2009 |
| Stream Advertising & Marketing Limited | Professional & scientific | 1999 |
| Streamline Financial Services Limited | Financial services | 2023 |
| Streetwear Kicks Ltd | Information & communication | 2025 |
| Strelitzia Accounting Limited | Professional & scientific | 2019 |
| Strength Base Limited | Other services | 2019 |
| Strength Redefined Calisthenics Limited | Arts & recreation | 2017 |
| Stretch Ceilings ME Limited | Construction | 2000 |
| Stride Media Management Limited | Information & communication | 2026 |
| Stripy Zebra Properties Limited | Real estate | 2018 |
| Stripy Zebra Property Management Limited | Real estate | 2004 |
| Strongbonds Property Investments Limited | Real estate | 2023 |
| Structice Engineering Consultants Ltd | Construction | 2017 |