| EVC South West Limited | Construction | 2018 |
| Events Lookout Ltd | Hospitality | 2025 |
| Evergreen Services (Devon) Ltd | Administrative & support | 2015 |
| Everything Louder Limited | Information & communication | 2005 |
| Evolve (U.K.) Ltd | Wholesale & retail | 2022 |
| EX Sports Indoor Games Ltd | Arts & recreation | 2025 |
| EX34 DNB Ltd | Administrative & support | 2026 |
| Exeter Anaesthetic Services Ltd | Health & social care | 2014 |
| Exeter Pain Consultant Service Limited | Health & social care | 2019 |
| Exmoor Accounts Ltd | Professional & scientific | 2025 |
| Exmoor Calvert Trust | Hospitality | 1991 |
| Exmoor Cottages Limited | Hospitality | 2023 |
| Exmoor Developments Ltd | Real estate | 2026 |
| Exmoor Electrical Ltd | Construction | 2022 |
| Exmoor Game Farm Limited | Agriculture & fishing | 2017 |
| Exmoor Heating Limited | Construction | 2002 |
| Exmoor Lifts Limited | Professional & scientific | 2022 |
| Exmoor Property Limited | Real estate | 2025 |
| Exmoor Trust | Other services | 1999 |
| Exosoft Limited | Information & communication | 2013 |
| Express Performance Limited | Wholesale & retail | 2023 |
| Extreme Cases Limited | Manufacturing | 2009 |
| EYE Nazar Limited | Health & social care | 2019 |
| Ezzat Medical Education Ltd | Education | 2025 |
| F E Norman Limited | Real estate | 1951 |
| F MCG Films Limited | Information & communication | 2018 |
| F Sanders Limited | Wholesale & retail | 2000 |
| F2 Sunnyside Road Ltd | Real estate | 2023 |
| Fabrecreations Limited | Administrative & support | 2008 |
| Fair Oak (Ashford) Management Company Limited | Real estate | 2022 |
| Fair Price Windows Limited | Construction | 2003 |
| Fairoak Developments Ashford Limited | Construction | 2019 |
| Fairview House Owners Association Limited | Households | 2013 |
| Falcon Quality Used Cars Limited | Wholesale & retail | 1999 |
| Falcons Community Sport Centre | Arts & recreation | 2011 |
| Falcons Gymnastic Academy Limited | Education | 2024 |
| Family Food Company Events Limited | Hospitality | 2018 |
| Family Food Company South West Limited | Hospitality | 2017 |
| Fantastic Illuminations Limited | Wholesale & retail | 2003 |
| Farley and Co Saddlery Ltd | Manufacturing | 2022 |
| Fawcus Estate Limited | Real estate | 2026 |
| Fawtola Company Limited | Health & social care | 2018 |
| FCG Bathrooms Ltd | Wholesale & retail | 2024 |
| FCG Kitchens Ltd | Construction | 2024 |
| Fdqspm Ltd | Professional & scientific | 2023 |
| Feral & Free Ltd | Manufacturing | 2026 |
| Fibrelight Developments Limited | Manufacturing | 2007 |
| Figure W Limited | Information & communication | 2006 |
| Fika (SW) Ltd | Professional & scientific | 2017 |
| File Scan Ltd | Information & communication | 2020 |
| Financial Advice Rooms Ltd | Financial services | 2017 |
| Finidhyn Limited | Professional & scientific | 2002 |
| Finishing Touch Flooring Limited | Wholesale & retail | 2009 |
| Fireball Beach Volleyball Ltd | Arts & recreation | 2021 |
| First AID at Hand Limited | Administrative & support | 2017 |
| First Computer Services Limited | Information & communication | 2003 |
| First Taxi Barnstaple Ltd | Transport & logistics | 2026 |
| Fitzgeraldhr Ltd | Administrative & support | 2012 |
| Fjecontracts Ltd | Construction | 2025 |
| Flavour SUM Food Limited | Manufacturing | 2025 |
| Fleming Regulatory Limited | Public administration | 2009 |
| Flexbury Park Court Limited | Households | 2024 |
| Flourish Foods and Logistics Ltd | Hospitality | 2025 |
| Flourish Healthcare Personnel Ltd | Administrative & support | 2025 |
| Flowki Plumbing Ltd | Construction | 2026 |
| Flypress Engineering Limited | Manufacturing | 2007 |
| Focalpoint Building Services Limited | Construction | 2007 |
| Focused Laser Systems Ltd | Wholesale & retail | 2019 |
| Fore Cross Property Management Ltd | Households | 2018 |
| Fortes Restaurant Limited | Hospitality | 2008 |
| Fortescue Drive Management Company Limited | Households | 2020 |
| Fortis Performance Ltd | Arts & recreation | 2024 |
| Forum Technologies Limited | Professional & scientific | 2019 |
| Forward Medical Health Limited | Health & social care | 2024 |
| Fourteen Acres Restaurant Ltd | Hospitality | 2026 |
| FOX and Moon Designs Limited | Wholesale & retail | 2025 |
| FOX Murphy Limited | Extraterritorial | 2015 |
| FOX Property Rentals Ltd | Real estate | 2025 |
| Fpopap Limited | Hospitality | 2019 |
| Fratelli (South West) Ltd. | Construction | 2014 |
| Fraycale Group Ltd | Other services | 2019 |
| Freddy's Fryer Ltd | Hospitality | 2026 |
| Freddy's Frying Wagon Ltd | Hospitality | 2026 |
| Freedom Apostolic Ministries Limited | Information & communication | 2016 |
| Freedom Community Alliance Limited | Health & social care | 2008 |
| Fresh Bread Marketing Limited | Professional & scientific | 2012 |
| Frilly Frocks Ltd | Wholesale & retail | 2014 |
| Frithelstock 4X4 Limited | Wholesale & retail | 2001 |
| Funky Ginger Company Ltd. | Professional & scientific | 2005 |
| Furlong Management Company Limited | Households | 2019 |
| Fuse Digital Limited | Professional & scientific | 2000 |
| Future Dimensions South West Limited | Professional & scientific | 2014 |
| Futuregrow (Devon) Ltd | Wholesale & retail | 2022 |
| G & a Kerslake Holdings Limited | Real estate | 2019 |
| G & a Kerslake Limited | Real estate | 2016 |
| G & B Scaffolding Contractors Limited | Construction | 2020 |
| G & N Construction (South West) Ltd | Construction | 2025 |
| G H Autoworx Limited | Wholesale & retail | 2025 |
| G J Davie Construction Limited | Construction | 2002 |
| G S Auto Tech Ltd | Wholesale & retail | 2010 |