| Chivenor Holdings Ltd | Real estate | 2022 |
| Chop and Chip Devon Tree Services Ltd | Agriculture & fishing | 2024 |
| Chris Collins Joinery Ltd | Manufacturing | 2014 |
| Christopher Gant Associates Limited | Professional & scientific | 2022 |
| Chsb Group Ltd | Financial services | 2024 |
| Cirrus TEK Consulting International Limited | Information & communication | 2007 |
| CJB Aviation Services Limited | Professional & scientific | 2018 |
| CJD Communications Ltd | Administrative & support | 2016 |
| CJM Couriers Ltd | Transport & logistics | 2025 |
| Clair Medhurst Ltd | Health & social care | 2026 |
| Clarity Business Solutions (SW) Ltd | Information & communication | 2002 |
| Clarke Heafield Limited | Arts & recreation | 2014 |
| Classic Car Clinic South West Ltd | Wholesale & retail | 2018 |
| Clausius UK Limited | Wholesale & retail | 2018 |
| Claydon Builders Ltd | Construction | 2012 |
| Clayewater Farms Limited | Agriculture & fishing | 2017 |
| Clayewater Homes Ltd | Construction | 2008 |
| Clayewater Planning Group Ltd | Other services | 2013 |
| Clayewater South West Limited | Construction | 2018 |
| Clearline Windows Ltd. | Construction | 2015 |
| Cleave Hill Developments Limited | Construction | 2002 |
| Cleave Point Management Company Limited | Households | 2006 |
| Clemeo Limited | Health & social care | 2025 |
| Cleone Classic Charters Ltd | Transport & logistics | 2016 |
| Clickwave Studio Ltd | Professional & scientific | 2024 |
| Cliffside Residents Management Company Limited | Households | 2006 |
| Clifton Heights Management Company (Holsworthy) Limited | Households | 2011 |
| Clive LEY Shoeing Services Limited | Other services | 2005 |
| Clock Tower Developments (Barnstaple) Limited | Construction | 2015 |
| Cloud Accountancy Solutions Ltd | Professional & scientific | 2011 |
| Cloud Financial Outsourcing Ltd | Extraterritorial | 2011 |
| CM Human Capital Solutions Limited | Professional & scientific | 2017 |
| CM Services SW Ltd | Administrative & support | 2025 |
| CMJ Accounting Ltd | Professional & scientific | 2023 |
| Cmja Pubs Limited | Hospitality | 2018 |
| Coached by Phil Ltd | Health & social care | 2024 |
| Coactum Technologies Limited | Professional & scientific | 2015 |
| Coast HR Ltd | Professional & scientific | 2019 |
| Coastal Enabling Services Ltd | Real estate | 2018 |
| Coastal Palms Developments Limited | Construction | 2018 |
| Coastal Palms Properties Ltd | Real estate | 2026 |
| Coastline Homes (SW) Ltd | Construction | 2026 |
| Coastline Sports Ltd | Arts & recreation | 2025 |
| Cobra Investco Limited | Financial services | 2024 |
| Codden Services Limited | Wholesale & retail | 1994 |
| Code Blonde Hair Studio Ltd | Other services | 2025 |
| CODE3 Ltd | Hospitality | 2024 |
| Coffee Lounge SW Limited | Other services | 2010 |
| Coleman Aviation Ltd | Transport & logistics | 2012 |
| Colin Essery Carpets Limited | Other services | 2002 |
| Colin Mccarthy Gardening Limited | Administrative & support | 2024 |
| College Court Sticklepath Limited | Real estate | 1998 |
| Colour Scan Limited | Professional & scientific | 2009 |
| Columbia Holdings Limited | Financial services | 2022 |
| Combe Flooring Ltd | Wholesale & retail | 2022 |
| Combe Martin Meats Limited | Manufacturing | 2017 |
| Combe Martin Scaffolding Limited | Agriculture & fishing | 2021 |
| Combe Surveyors Ltd | Professional & scientific | 2023 |
| Combrew Properties Ltd | Construction | 2025 |
| Commercial Services Events Ltd | Arts & recreation | 2017 |
| Commpliment Limited | Information & communication | 2008 |
| Community Choices Limited | Health & social care | 2008 |
| Compact Homes Ltd | Construction | 2021 |
| Compass Property Development Limited | Real estate | 2017 |
| Complete Building Solutions (North Devon) Limited | Construction | 2014 |
| Computantis Limited | Professional & scientific | 2022 |
| Concerned Medics Foundation Ltd | Education | 2025 |
| Connect Barnstaple Ltd | Transport & logistics | 2026 |
| Consort Productions Ltd | Arts & recreation | 2016 |
| Conspiracy-Clothing Ltd | Wholesale & retail | 2025 |
| Construction Design Consultancy Ltd | Professional & scientific | 2024 |
| Conturae Ltd | Professional & scientific | 2022 |
| Cook Electrical Ltd | Construction | 2013 |
| Cook, Create & Connect CIC | Hospitality | 2025 |
| Coombe Fisheries Limited | Manufacturing | 1980 |
| Coombe Kennels Ltd | Other services | 2020 |
| Coombefish Fleet Management Ltd | Agriculture & fishing | 2002 |
| Coombefish Fleetwood Ltd | Agriculture & fishing | 2025 |
| Coombefish Holdings Ltd | Financial services | 2015 |
| Coppice Lane Property Ltd | Real estate | 2025 |
| Copse Close Management Company Limited | Real estate | 2026 |
| Core Collagen Ltd | Wholesale & retail | 2025 |
| Cormorant Media Limited | Information & communication | 2006 |
| Corona Soft Drinks Ltd | Manufacturing | 2025 |
| Cottages on the Coast Limited | Extraterritorial | 2023 |
| Country Lane Services Ltd | Administrative & support | 2020 |
| Cousins and White Property Development Limited | Construction | 2025 |
| Cove Music Limited | Arts & recreation | 2016 |
| Cove Records Limited | Information & communication | 2008 |
| Cove View Management Company 2 Limited | Households | 2011 |
| Covestium Ltd | Financial services | 1996 |
| Cowes Capital Limited | Financial services | 2026 |
| COX Plant Water Borehole Drilling Limited | Water & waste | 2021 |
| COX Water Borehole Drilling Ltd | Construction | 2024 |
| CP International Limited | Professional & scientific | 2017 |
| CQC Holdings Limited | Financial services | 2011 |
| CQC Limited | Manufacturing | 1999 |
| CQC Training & Consultancy Ltd | Extraterritorial | 2025 |
| CR Build Solutions Ltd | Construction | 2023 |
| Craigen Engineering Limited | Manufacturing | 1987 |