| Rude Benz Ltd | Wholesale & retail | 2023 |
| Ruedas Bridal Ltd | Wholesale & retail | 2025 |
| Rulocum Limited | Professional & scientific | 2021 |
| Rumours & Custard Ltd | Arts & recreation | 2024 |
| Rupert Jones Finance Limited | Professional & scientific | 2012 |
| RUS Construct Limited | Construction | 2025 |
| Rushden Autos Limited | Wholesale & retail | 2025 |
| Rushnshop Ltd | Wholesale & retail | 2024 |
| Russell Agro Ltd | Information & communication | 2015 |
| Russell Signs Glass & Awnings Limited | Professional & scientific | 2026 |
| Rusty Bike Harlow Ltd | Hospitality | 2024 |
| Ruutedco Ltd | Wholesale & retail | 2025 |
| Ruzena Ltd | Construction | 2025 |
| Rwandan Diaspora Television Network (Rdtv) Ltd | Administrative & support | 2020 |
| Ryas IT Consulting Limited | Information & communication | 2025 |
| Rydelynk Ltd | Transport & logistics | 2025 |
| RYP Construction Ltd | Construction | 2021 |
| Ryton Limited | Wholesale & retail | 2019 |
| RZ8 Ltd | Professional & scientific | 2025 |
| S & Ripple Limited | Wholesale & retail | 2023 |
| S Bashir Consultancy Limited | Professional & scientific | 2016 |
| S Best Construction Ltd | Construction | 2025 |
| S K Painters and Decorators Ltd | Construction | 2022 |
| S MAN Solutions Ltd | Construction | 2025 |
| S R Aristocrats Limited | Hospitality | 2012 |
| S Sharp Facility Management Limited | Administrative & support | 2019 |
| S Wedding Management Limited | Hospitality | 2025 |
| S&A Haulage Ltd | Transport & logistics | 2024 |
| S&H Building Construction Limited | Construction | 2015 |
| S&J Citylink Ltd | Transport & logistics | 2025 |
| S&S Chauffeur Ltd | Transport & logistics | 2023 |
| S&Z Paradise Homes Ltd | Real estate | 2017 |
| S-Class Bodyworks Ltd | Wholesale & retail | 2025 |
| S. Ahmed Consulting Ltd | Professional & scientific | 2025 |
| S. P. M. Healthcare Limited | Health & social care | 2023 |
| S.C. Refinishing Ltd | Manufacturing | 1998 |
| S.Dore Limited | Health & social care | 2023 |
| S.I.K Metals Ltd | Wholesale & retail | 2022 |
| S.P.G Financial Services Limited | Professional & scientific | 2014 |
| S.S.S. Facade Solution Ltd | Construction | 2025 |
| S1 Auto Solutions Ltd | Wholesale & retail | 2020 |
| S2 Sloution Ltd | Information & communication | 2025 |
| S4 Real Estate Ltd | Real estate | 2022 |
| S4SECURITY Ltd | Administrative & support | 2016 |
| SA Installation and Maintenance Limited | Construction | 2021 |
| SA Property Management Ltd | Real estate | 2023 |
| SA Recruitment Limited | Administrative & support | 2025 |
| SA Ventures & Services Ltd | Transport & logistics | 2025 |
| SAA Hire Services Ltd | Transport & logistics | 2019 |
| Saadaat & Co Ltd | Transport & logistics | 2019 |
| Saag Trades Ltd | Wholesale & retail | 2021 |
| Saarc Academy London Ltd | Education | 2025 |
| Saathi Limited | Professional & scientific | 2025 |
| SAB Online Limited | Professional & scientific | 2022 |
| Sab's Facilities Ltd | Administrative & support | 2017 |
| SAB7786 Maintenance Ltd | Construction | 2025 |
| Saba Services Limited | Administrative & support | 2019 |
| Sabre Core Infrastructure Ltd | Information & communication | 2026 |
| Sabrina&Saleena Limited | Hospitality | 2026 |
| Sabs Wellness Limited | Health & social care | 2023 |
| Saddamic Ltd | Wholesale & retail | 2025 |
| Sadlab Ltd | Hospitality | 2026 |
| Sadz Tech Ltd | Wholesale & retail | 2021 |
| Saeedah Haque Limited | Wholesale & retail | 2024 |
| Saein Limited | Education | 2014 |
| SAF Construction & Builders Ltd | Construction | 2025 |
| SAF Fusion Limited | Wholesale & retail | 2025 |
| Safar London Ltd | Wholesale & retail | 2013 |
| Safe & Clean Limited | Other services | 2015 |
| Safe Cleaning and Maintenance Limited | Administrative & support | 2024 |
| Safe Distribution Ltd | Wholesale & retail | 2023 |
| Safe Shift CIC | Health & social care | 2025 |
| Safe Sound Security Ltd | Administrative & support | 2019 |
| Safeflow Global Limited | Transport & logistics | 2021 |
| Safehandmedi Ltd | Health & social care | 2025 |
| Safety First Cleaning Services Ltd | Administrative & support | 2010 |
| Safeway Distribution Limited | Wholesale & retail | 2014 |
| Safex Contractors Ltd | Construction | 2024 |
| Safs Automotive Limited | Wholesale & retail | 2022 |
| Safs Beauty Supplies Ltd | Wholesale & retail | 2022 |
| Safs Hair and Beauty Ltd | Wholesale & retail | 2022 |
| Safs Properties Ltd | Real estate | 2022 |
| Sage Construction Dom/Commercial Ltd | Construction | 2025 |
| Sahalmid Ltd | Manufacturing | 2025 |
| Sahara Aroma Ltd | Wholesale & retail | 2025 |
| Sahykas Limited | Construction | 2019 |
| SAI Consulting BD Ltd | Wholesale & retail | 2025 |
| SAI Romyen Thai Massage London Limited | Other services | 2017 |
| Saint Verc Ltd | Wholesale & retail | 2024 |
| Saint Vercetti Ltd | Manufacturing | 2023 |
| Saints Energy Limited | Energy | 2025 |
| Saints OFF Licence Limited | Wholesale & retail | 2013 |
| Sairex Ltd | Wholesale & retail | 2021 |
| SAJ Engineering Limited | Construction | 2013 |
| SAJ Engineering Survey Ltd | Construction | 2021 |
| SAJ Trade Limited | Wholesale & retail | 2024 |
| Sajj Limited | Real estate | 2013 |
| SAK Management Services Ltd | Professional & scientific | 2019 |
| Salaam Halal Meat and Grocery Ltd | Wholesale & retail | 2024 |
| Saladvision Limited | Wholesale & retail | 2022 |