| RN Cleaning Services Ltd | Administrative & support | 2023 |
| RN Property (Ayrshire) Ltd | Real estate | 2024 |
| RNK Inspection Services Ltd | Mining & quarrying | 2022 |
| Robbie Watson Limited | Administrative & support | 2021 |
| Robert Hamilton Contracting Ltd. | Agriculture & fishing | 2011 |
| Robert Mcfarlane Painters and Decorators Ltd | Construction | 2023 |
| Robert Mitchell Plumbing Ltd | Construction | 2023 |
| Robert Potter and Partners Ltd | Professional & scientific | 2023 |
| Robert Reid Consultancy Ltd | Professional & scientific | 2026 |
| Robertson Joinery Services Ltd | Construction | 2024 |
| Robertson Properties (Scotland) Limited | Real estate | 2019 |
| Robin & Marco FC Ltd | Hospitality | 2023 |
| Roccazana Limited | Wholesale & retail | 2024 |
| Rocket Monkey Roastery Ltd | Manufacturing | 2017 |
| ROD Contractors Ltd | Construction | 2016 |
| Rofm Holdings Ltd | Real estate | 2024 |
| Roft Property Ltd | Real estate | 2026 |
| Roksana Consulting LP | | 2014 |
| Ronamac Limited | Other services | 2007 |
| Roodlea Barn Ltd | Other services | 2019 |
| Roofing Solutions Ayrshire Ltd | Construction | 2021 |
| Rordio Limited | Arts & recreation | 2026 |
| Ross Clark Roofing Ltd | Construction | 2019 |
| Ross Flooring (Scotland) Limited | Wholesale & retail | 2025 |
| Rosseau Developments Ltd | Construction | 1985 |
| Roundhouse Loch Doon Limited | Hospitality | 2026 |
| Rowallan Renewables (Scotland) Ltd | Real estate | 2016 |
| Rowallan Renewals Limited | Construction | 2013 |
| Rowan Training Resources Ltd. | Professional & scientific | 2002 |
| Rowancross Limited | Administrative & support | 2000 |
| Rowmin Holdings Limited | Financial services | 2021 |
| Rowmin Ltd | Real estate | 2021 |
| Roxx Flooring Ltd | Construction | 2020 |
| Rozelle Property Ltd | Real estate | 2024 |
| RS Boost Limited | Professional & scientific | 2009 |
| RS Home Developments Ltd | Construction | 2025 |
| RSK Leisure Ltd | Arts & recreation | 2026 |
| Rtbc Scotland Ltd | Manufacturing | 2020 |
| RTC and Sons Ltd | Agriculture & fishing | 2024 |
| RTS Contracts Limited | Construction | 2000 |
| RTS Property Group Ltd | Real estate | 2023 |
| RTY BTL Ltd | Real estate | 2019 |
| RTY Commercial Ltd | Real estate | 2023 |
| RTY Flips Ltd | Real estate | 2019 |
| Rukeri Ltd | Wholesale & retail | 2012 |
| RUM CAY RUM Limited | Manufacturing | 2023 |
| Rumal Trade LP | | 2014 |
| Rutter Holdings Ltd. | Financial services | 2025 |
| RZI Maintenance Services Limited | Manufacturing | 2021 |
| S & B Cleaning Limited | Administrative & support | 2023 |
| S & D Masonry Ltd | Construction | 2023 |
| S & G Capital Ltd | Professional & scientific | 2019 |
| S & S Property AYR Ltd | Real estate | 2022 |
| S C Joinery Oak Frame Specialists Ltd | Construction | 2023 |
| S J Christy Limited | Education | 2012 |
| S M Europe Ltd. | Professional & scientific | 2007 |
| S MCF Fitness Ltd | Arts & recreation | 2023 |
| S Nisbet Logistics Ltd | Transport & logistics | 2023 |
| S Poland Limited | Agriculture & fishing | 2019 |
| S&R Limousines & Wedding Cars Ltd | Transport & logistics | 2024 |
| S.I.S.G. Enterprises Ltd. | Other services | 2003 |
| S.W Waste Ltd | Water & waste | 2023 |
| S23 Holdings Ltd | Financial services | 2024 |
| S80 Group Ltd | Construction | 2023 |
| SA Consultancy (Stranraer) Ltd | Professional & scientific | 2019 |
| Sabice Trading LP | | 2014 |
| SAC (LLP Nominees) Limited | Professional & scientific | 2009 |
| Safe Project Contracting Ltd | Administrative & support | 2025 |
| Safeguard Safety Systems Limited | Professional & scientific | 2024 |
| Safety Advisory Training Solutions Ltd | Professional & scientific | 2022 |
| Safety Management Scotland Ltd | Professional & scientific | 2017 |
| Sage Properties of AYR Ltd | Real estate | 2021 |
| SAI Aerospace Training Ltd | Education | 2024 |
| Saitech Estate Ltd | Administrative & support | 2017 |
| SAL Structures Sheet Metal Modification Ltd | Transport & logistics | 2019 |
| Salco Consulting Limited | Professional & scientific | 2018 |
| Sales Geek Glasgow East Limited | Wholesale & retail | 2024 |
| Salina Curry Ltd | Hospitality | 2025 |
| Salisbury Associates Limited | Professional & scientific | 2007 |
| Salorino Business LP | | 2014 |
| Salt and Grit Solutions Ltd | Wholesale & retail | 2010 |
| Salter Property (AYR) Limited | Real estate | 2024 |
| Saltire Cleaning Ltd | Arts & recreation | 2015 |
| Saltire Property Scotland Ltd | Real estate | 2019 |
| Salton Trade LP | | 2014 |
| Salvia Trade LP | | 2014 |
| SAM & Jerry Limited | Hospitality | 2024 |
| SAM Aerospace Engineering Services Limited | Manufacturing | 2023 |
| Sandyford Holdings Limited | Wholesale & retail | 2023 |
| Sanote Ltd | Administrative & support | 2023 |
| Santalia Corp. LP | | 2014 |
| Saqib Limited | Wholesale & retail | 2021 |
| SAS Plus Ltd | Other services | 2023 |
| Savoy Park Hotel Management Limited | Hospitality | 2023 |
| SBS Powerlines Ltd | Construction | 2023 |
| SC Operations Ltd | Extraterritorial | 2023 |
| Scaffolding-Access Ayrshire Ltd | Construction | 2023 |
| SCG Telecoms Limited | Information & communication | 2010 |
| Scmc Capital Limited | Financial services | 2023 |
| Scoat Ltd | Manufacturing | 2020 |