| Delamere Developments N/W Ltd | Construction | 2015 |
| Delaneys Gym Limited | Other services | 2024 |
| Delta Electrical Limited | Construction | 2018 |
| Deltagreen Ltd | Wholesale & retail | 2024 |
| Deltamead Trading Limited | Other services | 2026 |
| Delve Organisational Development Ltd | Professional & scientific | 2018 |
| Derama Properties Ltd | Real estate | 2023 |
| Deremma Limited | Professional & scientific | 2025 |
| Desi Point Limited | Hospitality | 2019 |
| Dessert Works Ltd | Hospitality | 2025 |
| Desserts LAB Ltd | Hospitality | 2026 |
| Devage Ltd | Information & communication | 2021 |
| Devcore Ltd | Wholesale & retail | 2026 |
| DEX Logistic Ltd | Transport & logistics | 2016 |
| Deylight Windows Ltd | Manufacturing | 2010 |
| Dhera Ltd | Wholesale & retail | 2016 |
| Diamond Beauty Centre Ltd | Other services | 2020 |
| DIE for Art Tattoo Limited | Other services | 2025 |
| Digi Dash Limited | Wholesale & retail | 2022 |
| Digifinex Holdings Ltd | Real estate | 2026 |
| Digital Filing Ltd | Professional & scientific | 2026 |
| Digital Foundry XYZ Ltd | Wholesale & retail | 2020 |
| Digital Hive Manchester Ltd | Information & communication | 2024 |
| Digital Punk Ltd | Manufacturing | 2020 |
| Dilva Limited | Arts & recreation | 2024 |
| Dimelux Services Ltd | Real estate | 2024 |
| Dina UK One Ltd | Hospitality | 2022 |
| Direct PAY Limited | Professional & scientific | 2019 |
| Directhearinghub.Com Ltd | Wholesale & retail | 2025 |
| Discwing Limited | Manufacturing | 2004 |
| Diva Beauty Salon Ltd | Other services | 2014 |
| Dizbiz Auto Spares Limited | Wholesale & retail | 2023 |
| DJ4 Contractors Limited | Construction | 2026 |
| Djalosurgicare Ltd | Health & social care | 2023 |
| DJM Shecons Ltd | Professional & scientific | 2022 |
| Djpc Technology Services Ltd | Information & communication | 2024 |
| DK Investments (NW) Limited | Real estate | 2022 |
| DK Services (NW) Limited | Administrative & support | 2010 |
| DL Home Improvement Solutions Ltd | Construction | 2025 |
| DLT Wood & Works Ltd | Manufacturing | 2025 |
| DMC Properties (NW) Limited | Real estate | 2024 |
| DO IT Halls Ltd | Construction | 2024 |
| Dobovi Ltd | Manufacturing | 2026 |
| Doctor Admin Services Ltd | Administrative & support | 2017 |
| Doctor Live UK CIC | Wholesale & retail | 2024 |
| Dolly Decades Limited | Manufacturing | 2016 |
| Dominion Security Limited | Administrative & support | 2019 |
| Donate-A-Light CIC | Health & social care | 2025 |
| Donnerism Ltd | Hospitality | 2025 |
| Doran Roofing Ltd | Construction | 2019 |
| Double B Transport Ltd | Transport & logistics | 2026 |
| Dovestone Services Ltd | Other services | 2018 |
| Dovestones Group Ltd | Financial services | 2023 |
| DP Painting Solutions Ltd | Construction | 2026 |
| DPD Painting Solutions Ltd | Construction | 2024 |
| Dproposal Ltd | Information & communication | 2023 |
| DR Jess Child Psychology Ltd | Health & social care | 2026 |
| DR Zain Asif Medical Services Ltd | Health & social care | 2025 |
| Drake Management Ltd | Information & communication | 2012 |
| Dramstone Ltd | Real estate | 2018 |
| Drawing Board Capital Limited | Real estate | 2024 |
| Dream BI Folding Doors Limited | Manufacturing | 2016 |
| Dream Properties & Developers Ltd | Real estate | 2023 |
| Dreamland (Preston) Ltd | Wholesale & retail | 2018 |
| DRG Installations Ltd | Construction | 2021 |
| Driverr Ltd | Transport & logistics | 2024 |
| DRT Clinics Ltd | Public administration | 2019 |
| Drum JAM Ltd | Arts & recreation | 2013 |
| Drummer BOY Estates Ltd. | Real estate | 1997 |
| DS & Co Accountants Ltd | Professional & scientific | 2022 |
| DSK Plastics & Building Supplies North West Ltd | Construction | 2020 |
| Dspotabor Limited | Arts & recreation | 2025 |
| DSR Property Limited | Real estate | 2019 |
| DSR Quantity Surveying Limited | Professional & scientific | 2016 |
| Dual-Stream Holdings Ltd | Financial services | 2021 |
| Dual-Stream Ltd | Administrative & support | 2013 |
| Dualcore Utilities Ltd | Professional & scientific | 2026 |
| Dugdale Cleaning Limited | Administrative & support | 2018 |
| Dukaan NO 99 Ltd | Wholesale & retail | 2018 |
| Duncan Buckley Limited | Wholesale & retail | 2026 |
| Durga Collection Ltd | Wholesale & retail | 2022 |
| Dusktech IT Services Ltd | Construction | 2024 |
| Dust Covers Limited | Manufacturing | 1951 |
| DW WH Ltd | Arts & recreation | 2025 |
| DW7ELITEFOOTBALL Ltd | Arts & recreation | 2026 |
| Dxtt Ltd | Other services | 2026 |
| Dymension Ltd | Wholesale & retail | 2021 |
| Dynamic Exchange Limited | Wholesale & retail | 2025 |
| E C Photography Ltd | Professional & scientific | 2024 |
| E M Leak Testing Ltd | Other services | 2014 |
| E T S 2020 Limited | Transport & logistics | 2024 |
| E&C Motors Ltd | Wholesale & retail | 2019 |
| E-Learner.Org Ltd | Education | 2024 |
| E. Reeds (A.U.L.) Limited | Financial services | 1984 |
| E2 Serve Ltd | Construction | 2026 |
| EAA Advisory Limited | Administrative & support | 2026 |
| EAC Security Ltd | Administrative & support | 2024 |
| Eagle Facilities Management Ltd | Administrative & support | 2025 |
| EAH Estates Ltd | Real estate | 2025 |
| EAR Clear Clinic Ltd | Health & social care | 2025 |