| Earlyeats Ltd | Hospitality | 2025 |
| East at Home Ltd | Wholesale & retail | 2022 |
| East Indian Takeaway Ltd | Hospitality | 2018 |
| East of England Limited | Wholesale & retail | 2019 |
| Easy Insure Limited | Financial services | 2020 |
| Easy Shutters Ltd | Wholesale & retail | 2025 |
| Easy Windows Ltd | Manufacturing | 2020 |
| EAT Simple Ltd | Wholesale & retail | 2023 |
| Ebibi Club Ltd | Wholesale & retail | 2026 |
| Eclectic Avenue Ltd | Hospitality | 2023 |
| Ecloud Online Limited | Wholesale & retail | 2017 |
| Ecloud Vapes Limited | Wholesale & retail | 2024 |
| Eco Boiler Scheme Limited | Construction | 2024 |
| Eco Power Technologies Ltd | Manufacturing | 2021 |
| Ecommerce Reports Ltd | Administrative & support | 2013 |
| Eden Davidson Limited | Other services | 2019 |
| Eden Fire & Security Ltd | Manufacturing | 2019 |
| Edge Property Lettings Limited | Real estate | 2024 |
| Edge Structural Design Limited | Professional & scientific | 2000 |
| Edgemaster Limited | Wholesale & retail | 2020 |
| Edgepoint Properties Ltd | Real estate | 2025 |
| Eesa Brothers Ltd | Transport & logistics | 2025 |
| Eesa Enterprizes Limited | Wholesale & retail | 2025 |
| Egbe OMO Ekiti Manchester CIC | Administrative & support | 2025 |
| Ehsan Enterprises Limited | Administrative & support | 1997 |
| Ehsys Fashion Ltd | Wholesale & retail | 2021 |
| EL Distributions Ltd | Wholesale & retail | 2025 |
| Elan Holdings Limited | Financial services | 2019 |
| ELC Projects Ltd | Manufacturing | 2022 |
| Elcco Enterprises Ltd | Wholesale & retail | 2019 |
| Elconnection Wholesaler Ltd | Wholesale & retail | 2018 |
| Electec NW Ltd | Construction | 2023 |
| Electrica Holdings Ltd | Financial services | 2024 |
| Electriphy Ltd | Energy | 2026 |
| Electronic Locking Systems Ltd | Construction | 2026 |
| Elegantposh Ltd | Other services | 2025 |
| Elements of Fragrance Limited | Manufacturing | 2020 |
| Eliquid Base Ltd | Wholesale & retail | 2025 |
| Elite Empire Limited | Other services | 2015 |
| Elite Maintenance & Development Limited | Construction | 2016 |
| Elite Mortgage & Finance Service Ltd | Financial services | 2017 |
| Elite Properties Estate Agency Limited | Real estate | 2024 |
| Elite Search Associates Limited | Administrative & support | 2018 |
| Elite Services and Consultancy Ltd | Construction | 2015 |
| Elite Trade (NW) Limited | Construction | 2018 |
| Ellison Rentals Limited | Real estate | 2019 |
| ELM Fulfilment Limited | Administrative & support | 2022 |
| Emerald Alliance Ltd | Health & social care | 2022 |
| Eminent Commercial Group Manchester Ltd. | Wholesale & retail | 2024 |
| Emma JAY Aesthetics and Brows Ltd | Other services | 2020 |
| Emmabest Properties Ltd | Real estate | 2026 |
| Emmanuel Shekkinah Ministries | Other services | 2003 |
| Emnourish UK Ltd | Wholesale & retail | 2016 |
| Emon Distribution Ltd | Wholesale & retail | 2024 |
| Empire Developments International Limited | Real estate | 2017 |
| Empire Luxury Cars Limited | Wholesale & retail | 2026 |
| Enacco Ltd | Professional & scientific | 2022 |
| Engage HR Ltd | Administrative & support | 2016 |
| Engage Learning Ltd | Education | 2025 |
| Entourage 21 Ltd | Information & communication | 2020 |
| Entwistle Aggregates Limited | Administrative & support | 2023 |
| Enviro Clean Stockport Ltd | Administrative & support | 2023 |
| Envirocare Plastics Recycling Ltd | Manufacturing | 2010 |
| Epic Emporium Limited | Wholesale & retail | 2024 |
| Equinehire Ltd | Administrative & support | 2024 |
| Ervi Removal & Cleaning Ltd | Transport & logistics | 2025 |
| ERW Essentials Ltd | Wholesale & retail | 2026 |
| Es&L Limited | Real estate | 2020 |
| Esoke Limited | Wholesale & retail | 2025 |
| Essa’Z Trading Ltd | Wholesale & retail | 2021 |
| Essnce Parfum Ltd | Wholesale & retail | 2026 |
| Etcc Consultancy Ltd | Manufacturing | 2007 |
| Ethicalgreen Limited | Professional & scientific | 2009 |
| Eudaimonia Developments Limited | Construction | 2016 |
| Euphoria Clothing Limited | Wholesale & retail | 2021 |
| Euphoria Sound and Events Limited | Arts & recreation | 2024 |
| Euro Training Group Holdings Limited | Professional & scientific | 2001 |
| Europe UK Enterprises Limited | Real estate | 1993 |
| Evade Martial Arts Limited | Education | 2026 |
| Evangelos Services Ltd | Professional & scientific | 2017 |
| Event Master Intl Limited | Other services | 2010 |
| Eventus Proholdings Ltd | Real estate | 2024 |
| Everest Cafe Ltd | Hospitality | 2022 |
| Evergrow Holdings Ltd | Wholesale & retail | 2025 |
| Eversafe Security Ltd | Administrative & support | 2025 |
| EVM Edit Ltd | Other services | 2025 |
| EVO Engineering Partnership LLP | | 2024 |
| Evolve Pharma Ltd | Health & social care | 2025 |
| Evora Imports Ltd | Wholesale & retail | 2025 |
| Evz.Bsl Limited | Professional & scientific | 2026 |
| Ewex Trading Ltd | Administrative & support | 2017 |
| EX COP Cars Ltd | Wholesale & retail | 2025 |
| EX Oblivione Ltd | Information & communication | 2024 |
| Excalibur Digital Services UK Ltd | Information & communication | 2026 |
| Excel Project Solutions Limited | Extraterritorial | 2022 |
| EXL 87 Limited | Wholesale & retail | 2025 |
| Expert Online Visibility Ltd | Information & communication | 2025 |
| Express Global Shipping Ltd | Transport & logistics | 2022 |
| EXS Distribution Limited | Wholesale & retail | 2013 |
| Ezydeal Limited | Wholesale & retail | 2025 |