| Centrix Park Management Company Limited | Real estate | 2009 |
| CFR Sales & Distribution Limited | Extraterritorial | 2012 |
| Chabriton Limited | Professional & scientific | 1911 |
| Change Begins Today CBT Limited | Health & social care | 2015 |
| Change Strategies Ltd | Professional & scientific | 2013 |
| Channel Design Limited | Professional & scientific | 2009 |
| Charles Exchange Limited | Wholesale & retail | 2025 |
| Charlii Smiths Limited | Extraterritorial | 2014 |
| Chelful Limited | Extraterritorial | 2013 |
| Chem Clean Services Limited | Administrative & support | 2003 |
| Cherry Tree Landscaping Ashbourne Ltd | Administrative & support | 2024 |
| CHI Living Ltd | Education | 2018 |
| Chiberta Ltd | Hospitality | 2025 |
| Chiles Really Good Ideas Ltd | Other services | 2025 |
| Chloe Mediumship Ltd | Professional & scientific | 2022 |
| Chloe Mediumship Media Ltd | Professional & scientific | 2025 |
| Chris Mather 0847 Limited | Extraterritorial | 2015 |
| Chrome Property Management Ltd | Real estate | 2022 |
| Church Farm Community Ltd | Other services | 2001 |
| Church View Lets Limited | Hospitality | 2025 |
| Church View Retreat Ltd | Hospitality | 2019 |
| Churchfields Barns Management Company Limited | Real estate | 2003 |
| Churnet Valley Veterinary Clinic Limited | Professional & scientific | 2007 |
| Cinergise Limited | Information & communication | 2019 |
| CJ Burton Properties Ltd | Real estate | 2021 |
| Classic Additions Limited | Wholesale & retail | 1990 |
| Classic Marine Services Limited | Professional & scientific | 2021 |
| Classic Motorcycle Decals Limited | Wholesale & retail | 2015 |
| Click Property & Investments Ltd | Real estate | 2020 |
| Clock Woodburners Limited | Wholesale & retail | 2019 |
| Cloud Formations Ltd | Information & communication | 2022 |
| Clover Kitchens Limited | Wholesale & retail | 2002 |
| Clowes Developments (Mfds) Limited | Extraterritorial | 2009 |
| Clowes Developments (Midlands) Limited | Real estate | 1986 |
| Clowes Developments (North West) Limited | Real estate | 1988 |
| Clowes Developments (UK) Limited | Real estate | 1964 |
| Clowes Estates Limited | Real estate | 1968 |
| Clowes Securities (West Midlands) LLP | | 2007 |
| Clowes Westerman Limited | Real estate | 2004 |
| Clsa Solutions Ltd | Administrative & support | 2015 |
| CM Natural Energy Ltd | Energy | 2012 |
| CM Services & Supplies Ltd | Manufacturing | 1997 |
| Coactivation Ltd | Professional & scientific | 2016 |
| Coates and Partners Limited | Professional & scientific | 2002 |
| Coates Commercial & Domestic Civils Ltd | Construction | 2021 |
| Cobalt Create Limited | Information & communication | 2021 |
| Codeck Ltd | Construction | 2011 |
| Coldcarr Recycling Limited | Water & waste | 2002 |
| Coles Auto Electrical Services Limited | Wholesale & retail | 2001 |
| Colin Amos Builders Limited | Construction | 2002 |
| Colison Limited | Information & communication | 2007 |
| Collaboration Musical Theatre | Arts & recreation | 2023 |
| Collie Associates Limited | Professional & scientific | 1998 |
| Compton Media Ltd. | Information & communication | 2004 |
| Comptonbb Ltd | Hospitality | 2025 |
| Concept & Detail Ltd | Professional & scientific | 2012 |
| Confighr Systems Consulting Ltd | Information & communication | 2025 |
| Conquest Writing Limited | Arts & recreation | 2023 |
| Construction Management Global Limited | Construction | 2011 |
| Cooper Assurance Services LLP | | 2013 |
| Cosmic Interface Ltd | Information & communication | 2025 |
| Cosy Casa Home Ltd | Extraterritorial | 2024 |
| Cosyshepherdshuts.Com Limited | Real estate | 2023 |
| Cotton Developments Limited | Construction | 2004 |
| Count of TEN Ltd | Administrative & support | 2005 |
| Country Escapes Ltd | Hospitality | 2019 |
| Couplings Ltd | Hospitality | 2024 |
| Covert Bids Ltd | Arts & recreation | 2024 |
| Coxon Group Limited | Financial services | 2024 |
| CPD Electrical/Mechanical Contractors Ltd | Manufacturing | 2020 |
| CPJ Environmental Services Limited | Construction | 2001 |
| CPJ Investments Ltd | Financial services | 2020 |
| CPJ Property Limited | Real estate | 2022 |
| Crafts Cornucopia Ltd | Arts & recreation | 2013 |
| Cravenhill Holdings Limited | Administrative & support | 2017 |
| Crawley Consultants (Spondon) Limited | Professional & scientific | 2012 |
| Create Your Perfect Spaces Ltd | Construction | 2023 |
| Creative Peaks CIC | Arts & recreation | 2023 |
| Crellin Consulting Ltd | Information & communication | 2024 |
| Cricketcoach Ltd | Arts & recreation | 2026 |
| Crofton Close Management Company Ltd | Households | 2021 |
| Cross Stores (Repton) Limited | Wholesale & retail | 2006 |
| Crosslow Lane Coaches Ltd | Transport & logistics | 2022 |
| Crown Park Management Company Limited | Real estate | 2020 |
| Crowtrees Farm Limited | Agriculture & fishing | 2021 |
| CS & L Limited | Administrative & support | 1997 |
| Cubley Cottage Farm Ltd | Agriculture & fishing | 2015 |
| Culland Capital Advisors Limited | Administrative & support | 2003 |
| Cunningham-Sawyer Law Limited | Professional & scientific | 2021 |
| CW Sellors Group Ltd | Financial services | 2026 |
| CWP Business Solutions Limited | Professional & scientific | 2019 |
| D & a Dickinson Limited | Agriculture & fishing | 2009 |
| D & D Builders & Contractors Limited | Construction | 2002 |
| D a & F Brown Limited | Agriculture & fishing | 2003 |
| D F Baxter Holdings Limited | Professional & scientific | 1988 |
| D F Naylor Limited | Wholesale & retail | 2018 |
| D G Ditchfield Limited | Agriculture & fishing | 2007 |
| D J M Agricultural Services Limited | Agriculture & fishing | 2013 |
| D R Joinery & Construction Ltd | Construction | 2023 |
| D Salsbury Limited | Education | 2011 |