| Primrose and Bennett Landscapes Ltd | Professional & scientific | 2025 |
| Prince 83 Limited | Real estate | 2020 |
| Prinden Limited | Extraterritorial | 2021 |
| Progressive Accounting Ltd | Professional & scientific | 2022 |
| Property Matters Burton Ltd | Real estate | 2021 |
| Propolis Management Limited | Professional & scientific | 2016 |
| Prosephra Ltd | Information & communication | 2022 |
| Protech Renewed Ltd | Wholesale & retail | 2026 |
| Proteios Holdings Limited | Financial services | 2024 |
| Proteios Limited | Manufacturing | 2019 |
| Prutton Limited | Health & social care | 2009 |
| PSH Barber 2 Ltd | Other services | 2025 |
| PSH Barbershop Ltd | Other services | 2026 |
| PSH UK Barbers Ltd | Other services | 2026 |
| Ptk-Gb Ltd | Wholesale & retail | 2013 |
| PUB in the Woods Ltd | Hospitality | 2024 |
| Puffin Green Solutions Limited | Professional & scientific | 2023 |
| Purely Floors and Blinds Limited | Wholesale & retail | 2009 |
| Purple Buddy Ltd | Other services | 2025 |
| Pyford Ltd | Construction | 2018 |
| QBB Limited | Professional & scientific | 2007 |
| Qegsmat | Education | 2011 |
| Quaesitum Ltd | Professional & scientific | 2011 |
| Qualitac Limited | Wholesale & retail | 2008 |
| Quality in a Box Limited | Professional & scientific | 2003 |
| Quinton Consulting Ltd | Administrative & support | 2017 |
| R & D Extrusions Limited | Manufacturing | 2006 |
| R a James Clocks Limited | Other services | 2008 |
| R and C Management Consultants Limited | Professional & scientific | 2018 |
| R B Butler Limited | Wholesale & retail | 2022 |
| R D Haslam Agricultural Services Limited | Manufacturing | 2022 |
| R J Popple Joinery Limited | Construction | 2021 |
| R L Financial Services Limited | Financial services | 2008 |
| R L Gosling Lettings Ltd | Real estate | 2025 |
| R Pilkington Services Limited | Transport & logistics | 2008 |
| R T S Building Contractors Limited | Construction | 2019 |
| R. W. Chell Limited | Construction | 2013 |
| R3VO LLP | | 2025 |
| Radar Finance & Leasing Limited | Financial services | 2004 |
| Radar Property Co Ltd | Households | 2025 |
| Radbourne Homes Ltd | Construction | 2021 |
| Radmore (Staffordshire) Limited | Construction | 2014 |
| Radmore Limited | Construction | 2012 |
| RAJ Sanghani Limited | Information & communication | 2007 |
| RAK MAK MAK Limited | Wholesale & retail | 2022 |
| Ramsey Douglas Limited | Professional & scientific | 2020 |
| Ramshorn Investments Limited | Real estate | 2016 |
| Raptor Grafix Limited | Professional & scientific | 2013 |
| Ratcat Limited | Information & communication | 2019 |
| Ravensdale Event Hire Limited | Administrative & support | 2022 |
| Ravensdale Events Limited | Extraterritorial | 2022 |
| RAW Promo Limited | Other services | 2013 |
| RC and AL Adams Limited | Agriculture & fishing | 2008 |
| RD Therapy Ltd | Health & social care | 2021 |
| Re-Worked Vintage Interiors Ltd | Wholesale & retail | 2026 |
| Reai Estate Revolution Ltd | Education | 2025 |
| Rebecca Longdon Limited | Administrative & support | 2025 |
| Red Chilli Ashbourne (Express) Ltd | Hospitality | 2025 |
| Red Hill Fencing Midlands Limited | Administrative & support | 2014 |
| Red PEN Communications Limited | Professional & scientific | 2016 |
| Red Red Consulting Limited | Professional & scientific | 2014 |
| Redfern Joinery Limited | Construction | 2019 |
| Redhill Livestock Transport Limited | Transport & logistics | 2024 |
| Redlab Ltd | Real estate | 2016 |
| Reeds Travel Ltd | Hospitality | 2024 |
| Refinex Market Solutions Limited | Professional & scientific | 2025 |
| Reformation Studio Ltd | Professional & scientific | 2023 |
| Regalplay Developments Limited | Extraterritorial | 1989 |
| Renaissance Garden Company Limited | Administrative & support | 2003 |
| Restoration Music Limited | Administrative & support | 1983 |
| Resurgence Consulting Limited | Professional & scientific | 2022 |
| Retail INV Limited | Real estate | 2025 |
| Retro Parts Group Limited | Wholesale & retail | 2015 |
| Rewild & Thrive C.I.C. | Health & social care | 2025 |
| RFL Holdings Ltd | Financial services | 2022 |
| RH Holidays Limited | Hospitality | 2025 |
| RH NDT Consulting Ltd | Professional & scientific | 2022 |
| RHI Service Limited | Professional & scientific | 2013 |
| Rhodes Wealth Management Limited | Financial services | 2010 |
| Riber View Management Company Limited | Households | 2019 |
| Richard Kelly Ltd | Administrative & support | 2019 |
| Richard Newell Cheese & Dairy Services Ltd | Professional & scientific | 2019 |
| Ridgeway Accountancy Services Limited | Professional & scientific | 2002 |
| Riley's of Derbyshire Ltd | Hospitality | 2018 |
| Rippa Ltd | Real estate | 2023 |
| Risicol Limited | Water & waste | 2009 |
| RJG Consulting Limited | Administrative & support | 2008 |
| RJL Property Limited | Real estate | 2017 |
| Robin Beeston Limited | Wholesale & retail | 2003 |
| Robinson & LEE Steel Decking Limited | Construction | 2013 |
| Robotaxi Ltd | Transport & logistics | 2014 |
| Roger Cooper Estates & FM Limited | Extraterritorial | 2015 |
| RON Morton Farming Limited | Agriculture & fishing | 1997 |
| Roston Agricultural Services Limited | Wholesale & retail | 2011 |
| Roston Castings Limited | Manufacturing | 1972 |
| Roston Farms Limited | Agriculture & fishing | 2019 |
| Round Oak Dressage Ltd | Agriculture & fishing | 2019 |
| Round Oak Renewables Limited | Construction | 2023 |
| Royann Associates Limited | Professional & scientific | 2021 |
| RPC Commercials Ltd | Wholesale & retail | 2006 |