| ST. John's Court (Northenden) Management Company Limited | Households | 1998 |
| ST. Richard's Close Management Company Limited | Real estate | 2003 |
| ST4E Limited | Professional & scientific | 2023 |
| Staerk DOR Limited | Construction | 2013 |
| Staffordshire Student Living Limited | Real estate | 2018 |
| Stainfield Limited | Administrative & support | 2014 |
| Staircase Consulting Limited | Information & communication | 2025 |
| Stakehill Distribution Properties LLP | | 2009 |
| Stame Property Services Limited | Real estate | 2021 |
| Stamford Advisory Limited | Professional & scientific | 2026 |
| Stamford Arms Development Ltd | Construction | 2016 |
| Stamford Arms Estate Management Company Limited | Households | 2023 |
| Stamford Brook Pre-School Limited | Education | 2018 |
| Stamford CFO Ltd | Professional & scientific | 2023 |
| Stamford Court (Currier Lane) Management Limited | Real estate | 1987 |
| Stamford Finance 1 Limited | Financial services | 2025 |
| Stamford Finance 2 Limited | Financial services | 2025 |
| Stamford Finance 3 Limited | Financial services | 2025 |
| Stamford Finance 4 Limited | Financial services | 2025 |
| Stamford Finance 5 Limited | Financial services | 2025 |
| Stamford Finance Limited | Financial services | 2022 |
| Stamford Inspection Services Limited | Professional & scientific | 2025 |
| Stamford Investments Group Limited | Financial services | 2025 |
| Stamford New Road Ltd | Hospitality | 2016 |
| Stamford New Road Property Ltd | Construction | 2016 |
| Stamford Park Construction Limited | Professional & scientific | 2024 |
| Stamford Park Investments Ltd | Real estate | 2025 |
| Stamford Quarter Therapies Ltd | Real estate | 2025 |
| Stand Communications Ltd | Professional & scientific | 2021 |
| Standard Practice Ltd | Professional & scientific | 2018 |
| Standish Lodge Limited | Hospitality | 2017 |
| Stanley Court Estate Management Ltd | Households | 2015 |
| Stanley MAY Limited | Manufacturing | 2014 |
| Star Gladiators Ltd | Arts & recreation | 2015 |
| Star Sine Ltd | Administrative & support | 2022 |
| Stardew Technologies Limited | Information & communication | 2021 |
| Starlea Limited | Professional & scientific | 2014 |
| Starleda International Limited | Wholesale & retail | 2009 |
| Starlight (Hale) Limited | Health & social care | 2021 |
| Starlight Dance School Ltd | Arts & recreation | 2024 |
| Starling Wood Press Ltd | Information & communication | 2024 |
| Starry Skies Limited | Education | 2009 |
| Starstore Limited | Households | 1984 |
| Starving MAN Limited | Hospitality | 2010 |
| Starwell Consultancy Limited | Professional & scientific | 2017 |
| Starwolf Ltd | Information & communication | 2017 |
| Statimeter Company Limited(The) | Manufacturing | 1937 |
| Station Courtyard Management Company Limited | Real estate | 2023 |
| Statis Energy and Risk Limited | Professional & scientific | 2025 |
| Statlab Medical Products Holdings UK Limited | Financial services | 2021 |
| Statwick Limited | Information & communication | 2023 |
| Stay Lusso Holdings Limited | Financial services | 2019 |
| Stay Lusso Operations Limited | Real estate | 2019 |
| STB Projects Ltd | Real estate | 2019 |
| Stealth Integrity Management Limited | Professional & scientific | 2023 |
| Steel Films Limited | Information & communication | 2026 |
| Steinhaus Properties Limited | Construction | 2025 |
| Stellar Books LLP | | 2013 |
| Stenic Business Solutions Limited | Professional & scientific | 2019 |
| Step Refactor Limited | Administrative & support | 2016 |
| STEP2 Discovery UK, Limited | Wholesale & retail | 2021 |
| Stephen More Electrical Limited | Administrative & support | 2014 |
| Stepz Auto Ltd | Wholesale & retail | 2023 |
| Sterilin Limited | Manufacturing | 2008 |
| Sterling Capital Investments Limited | Professional & scientific | 2014 |
| Sterling Event Group Limited | Administrative & support | 2009 |
| Sterling Fixed Property Receivers Limited | Financial services | 2017 |
| Sterling Stores Limited | Wholesale & retail | 2022 |
| Steve Barber Ltd | Wholesale & retail | 2023 |
| Steve Douglas Resourcing Limited | Administrative & support | 2022 |
| Steve Hallam Ltd | Manufacturing | 1999 |
| Steve Halsey Consulting Limited | Professional & scientific | 2017 |
| Steve Rawes Elite Football Performance Consultancy Ltd. | Arts & recreation | 2017 |
| Steve Sadler Consulting Ltd | Administrative & support | 2012 |
| Stevelaw Properties Limited | Real estate | 2015 |
| Steven Grainger Design Limited | Information & communication | 2010 |
| Steven Stone Limited | Wholesale & retail | 1957 |
| Stewart Forensic Consultants Ltd | Professional & scientific | 2010 |
| STI Property Management Ltd | Real estate | 2020 |
| Stickee Holdings Ltd | Information & communication | 2021 |
| Stickee Technology Limited | Information & communication | 2008 |
| Stickies Ltd | Manufacturing | 2026 |
| Still Room Drinks Ltd | Manufacturing | 2022 |
| Stillwater Investment Ltd | Real estate | 2020 |
| Stirling Lingerie Limited | Professional & scientific | 1936 |
| Stirling Retail Park Limited Partnership | | 2004 |
| Stirling Retail Park Nominee Limited | Administrative & support | 2004 |
| Stll Consultancy PVT Ltd | Financial services | 2024 |
| STO Sweden Limited | Administrative & support | 2025 |
| STOCKM8 Ltd | Administrative & support | 2020 |
| Stockport Drinks Ltd | Hospitality | 2025 |
| Stockport Road Management Company Limited | Administrative & support | 2016 |
| Stockport Supported Tenancy Ltd | Other services | 2025 |
| Stockport Ventures Limited | Administrative & support | 2011 |
| Stoic's Capital Investments Ltd. | Hospitality | 2025 |
| Stoica Electric Limited | Construction | 2016 |
| Stone & Watson Ltd | Wholesale & retail | 2024 |
| Stone and Porcelain Limited | Wholesale & retail | 2021 |
| Stone Digital Limited | Professional & scientific | 2020 |
| Stone Group Limited | Financial services | 2020 |